Role of phosphatidylinositol 3'-kinase/AKT pathway in diffuse large B-cell lymphoma survival. AKKS Uddin S, Hussain AR, Siraj AK, Manogaran PS, Al-Jomah NA, Moorji A ... Blood 108 (13), 4178-86, 2006 | 304 | 2006 |
Curcumin induces apoptosis via inhibition of PI3′-kinase/AKT pathway in acute T cell leukemias AR Hussain, M Al-Rasheed, PS Manogaran, KA Al-Hussein, LC Platanias, ... Apoptosis 11, 245-254, 2006 | 210 | 2006 |
Cross-talk between NFkB and the PI3-kinase/AKT pathway can be targeted in primary effusion lymphoma (PEL) cell lines for efficient apoptosis AR Hussain, SO Ahmed, M Ahmed, OS Khan, S Al AbdulMohsen, ... PloS one 7 (6), e39945, 2012 | 182 | 2012 |
Genome-wide expression analysis of Middle Eastern colorectal cancer reveals FOXM1 as a novel target for cancer therapy S Uddin, M Ahmed, A Hussain, J Abubaker, N Al-Sanea, A AbdulJabbar, ... The American journal of pathology 178 (2), 537-547, 2011 | 174 | 2011 |
Sanguinarine-dependent induction of apoptosis in primary effusion lymphoma cells AR Hussain, NA Al-Jomah, AK Siraj, P Manogaran, K Al-Hussein, ... Cancer research 67 (8), 3888-3897, 2007 | 151 | 2007 |
Curcumin suppresses growth and induces apoptosis in primary effusion lymphoma S Uddin, AR Hussain, PS Manogaran, K Al-Hussein, LC Platanias, ... Oncogene 24 (47), 7022-7030, 2005 | 145 | 2005 |
Cyclooxygenase‐2 inhibition inhibits PI3K/AKT kinase activity in epithelial ovarian cancer S Uddin, M Ahmed, A Hussain, L Assad, F Al‐Dayel, P Bavi, ... International journal of cancer 126 (2), 382-394, 2010 | 131 | 2010 |
Curcumin suppresses constitutive activation of nuclear factor-κB and requires functional Bax to induce apoptosis in Burkitt's lymphoma cell lines AR Hussain, M Ahmed, NA Al-Jomah, AS Khan, P Manogaran, M Sultana, ... Molecular cancer therapeutics 7 (10), 3318-3329, 2008 | 131 | 2008 |
Inhibition of phosphatidylinositol 3′-kinase/AKT signaling promotes apoptosis of primary effusion lymphoma cells S Uddin, AR Hussain, KA Al-Hussein, PS Manogaran, A Wickrema, ... Clinical cancer research 11 (8), 3102-3108, 2005 | 123 | 2005 |
Thymoquinone suppresses growth and induces apoptosis via generation of reactive oxygen species in primary effusion lymphoma AR Hussain, M Ahmed, S Ahmed, P Manogaran, LC Platanias, SN Alvi, ... Free radical biology and medicine 50 (8), 978-987, 2011 | 116 | 2011 |
Leptin-R and its association with PI3K/AKT signaling pathway in papillary thyroid carcinoma S Uddin, P Bavi, AK Siraj, M Ahmed, M Al-Rasheed, AR Hussain, ... Endocrine-related cancer 17 (1), 191-202, 2010 | 109 | 2010 |
Resveratrol suppresses constitutive activation of AKT via generation of ROS and induces apoptosis in diffuse large B cell lymphoma cell lines AR Hussain, S Uddin, R Bu, OS Khan, SO Ahmed, M Ahmed, ... PLoS One 6 (9), e24703, 2011 | 99 | 2011 |
Sequence variations in EBNA-1 may dictate restriction of tissue distribution of Epstein-Barr virus in normal and tumour cells MI Gutierrez, A Raj, G Spangler, A Sharma, A Hussain, JG Judde, ... Journal of general virology 78 (7), 1663-1670, 1997 | 97 | 1997 |
Bax is frequently compromised in Burkitt’s lymphomas with irreversible resistance to Fas-induced apoptosis MI Gutiérrez, B Cherney, A Hussain, H Mostowski, G Tosato, I Magrath, ... Cancer research 59 (3), 696-703, 1999 | 94 | 1999 |
Inhibition of phosphatidylinositol 3′-kinase induces preferentially killing of PTEN-null T leukemias through AKT pathway S Uddin, A Hussain, K Al-Hussein, LC Platanias, KG Bhatia Biochemical and biophysical research communications 320 (3), 932-938, 2004 | 88 | 2004 |
Bortezomib (Velcade) induces p27Kip1 expression through S-phase kinase protein 2 degradation in colorectal cancer S Uddin, M Ahmed, P Bavi, R El-Sayed, N Al-Sanea, A AbdulJabbar, ... Cancer research 68 (9), 3379-3388, 2008 | 87 | 2008 |
FoxM1 and its association with matrix metalloproteinases (MMP) signaling pathway in papillary thyroid carcinoma M Ahmed, S Uddin, AR Hussain, A Alyan, Z Jehan, F Al-Dayel, ... The Journal of Clinical Endocrinology & Metabolism 97 (1), E1-E13, 2012 | 80 | 2012 |
Fatty acid synthase and AKT pathway signaling in a subset of papillary thyroid cancers S Uddin, AK Siraj, M Al-Rasheed, M Ahmed, R Bu, JN Myers, A Al-Nuaim, ... The Journal of Clinical Endocrinology & Metabolism 93 (10), 4088-4097, 2008 | 80 | 2008 |
Prognostic significance of XIAP expression in DLBCL and effect of its inhibition on AKT signalling AR Hussain, S Uddin, M Ahmed, R Bu, SO Ahmed, J Abubaker, M Sultana, ... The Journal of pathology 222 (2), 180-190, 2010 | 75 | 2010 |
Bortezomib stabilizes mitotic cyclins and prevents cell cycle progression via inhibition of UBE2C in colorectal carcinoma P Bavi, S Uddin, M Ahmed, Z Jehan, R Bu, J Abubaker, M Sultana, ... The American journal of pathology 178 (5), 2109-2120, 2011 | 71 | 2011 |