关注
Kiruphagaran Thangaraju
Kiruphagaran Thangaraju
Center for Blood Oxygen Transport and Hemostasis, University of Maryland, Baltimore
在 som.umaryland.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Extracellular vesicles from red blood cells and their evolving roles in health, coagulopathy and therapy
K Thangaraju, SN Neerukonda, U Katneni, PW Buehler
International journal of molecular sciences 22 (1), 153, 2020
1152020
Biological and Clinical Factors Contributing to the Metabolic Heterogeneity of Hospitalized Patients with and without COVID-19
Cells 10 (9), 2293, 2021
452021
Isopeptidase activity of human transglutaminase 2: disconnection from transamidation and characterization by kinetic parameters
R Király, K Thangaraju, Z Nagy, R Collighan, Z Nemes, M Griffin, L Fésüs
Amino acids 48 (1), 31-40, 2016
332016
The alternative initiation factor eIF2A plays key role in RAN translation of myotonic dystrophy type 2 CCUG• CAGG repeats
SK Tusi, L Nguyen, K Thangaraju, J Li, JD Cleary, T Zu, LPW Ranum
Human molecular genetics 30 (11), 1020-1029, 2021
172021
Coagulation potential and the integrated omics of extracellular vesicles from COVID-19 positive patient plasma
S Setua, K Thangaraju, M Dzieciatkowska, RB Wilkerson, T Nemkov, ...
Scientific reports 12 (1), 22191, 2022
132022
The impact of age and BMI on the VWF/ADAMTS13 axis and simultaneous thrombin and plasmin generation in hospitalized COVID-19 patients
K Thangaraju, U Katneni, IJ Akpan, K Tanaka, T Thomas, S Setua, ...
Frontiers in Medicine 8, 817305, 2022
102022
Genomic variants reveal differential evolutionary constraints on human transglutaminases and point towards unrecognized significance of transglutaminase 2
K Thangaraju, R Király, MA Demeny, J András Mótyán, M Fuxreiter, ...
PloS one 12 (3), e0172189, 2017
82017
A pharmacokinetic and plasmin-generation pharmacodynamic assessment of a tranexamic acid regimen designed for cardiac surgery with cardiopulmonary bypass
ER Strauss, S Li, R Henderson, R Carpenter, D Guo, K Thangaraju, ...
Journal of Cardiothoracic and Vascular Anesthesia 36 (8), 2473-2482, 2022
72022
Computational analyses of the effect of novel amino acid clusters of human transglutaminase 2 on its structure and function
K Thangaraju, R Király, JA Mótyán, VA Ambrus, M Fuxreiter, L Fésüs
Amino acids 49, 605-614, 2017
72017
Real-time kinetic method to monitor isopeptidase activity of transglutaminase 2 on protein substrate
K Thangaraju, B Biri, G Schlosser, B Kiss, L Nyitray, L Fésüs, R Király
Analytical Biochemistry 505, 36-42, 2016
62016
Mechanical stimuli such as shear stress and piezo1 stimulation generate red blood cell extracellular vesicles
GS Sangha, CM Weber, RM Sapp, S Setua, K Thangaraju, M Pettebone, ...
Frontiers in Physiology 14, 1246910, 2023
42023
In vitro effects of emicizumab on activated clotting time in blood samples from cardiac surgical patients
KA Tanaka, R Henderson, K Thangaraju, Y Morita, MA Mazzeffi, E Strauss, ...
Haemophilia 28 (1), 183-190, 2022
42022
The Molecular Size of Bioengineered Oxygen Carriers Determines Tissue Oxygenation in a Hypercholesterolemia Guinea Pig Model of Hemorrhagic Shock and Resuscitation
DR Lamb, A Greenfield, K Thangaraju, S Setua, G Eiker, Q Wang, ...
Molecular Pharmaceutics 20 (11), 5739-5752, 2023
22023
Biophysical Analysis and Preclinical Pharmacokinetics–Pharmacodynamics of Tangential Flow Filtration Fractionated Polymerized Human Hemoglobin as a Red Blood Cell Substitute
A Greenfield, DR Lamb, X Gu, K Thangaraju, S Setua, A Yahya, A Vahedi, ...
Biomacromolecules 24 (4), 1855-1870, 2023
22023
Metabolic and Proteomic Divergence Is Present in Circulating Monocytes and Tissue-Resident Macrophages from Berkeley Sickle Cell Anemia and β-Thalassemia Mice
C Lisk, F Cendali, S Setua, K Thangaraju, DI Pak, D Swindle, ...
Journal of Proteome Research 22 (9), 2925-2935, 2023
12023
Extracellular Vesicle Size Reveals Cargo Specific to Coagulation and Inflammation in Pediatric and Adult Sickle Cell Disease
K Thangaraju, S Setua, C Lisk, D Swindle, D Stephenson, ...
Clinical and Applied Thrombosis/Hemostasis 29, 10760296231186144, 2023
12023
Identification of repeat expansion mutations using novel deactivated-Cas9-based tools
L Nguyen, K Thangaraju, R Ajredini, PT Ranum, BL Davidson, ET Wang, ...
AAIC Neuroscience Next, 2020
2020
Significance of evolutionary changes in human transglutaminases
K Thangaraju, M Fuxreiter, L Fésüs
AMINO ACIDS 47 (8), 1629-1629, 2015
2015
Amino acid variants in human transglutaminase 2 and their biological relevance
K Thangaraju
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