Therapeutic drug monitoring of oral targeted antineoplastic drugs A Mueller-Schoell, SL Groenland, O Scherf-Clavel, M van Dyk, ... European journal of clinical pharmacology 77, 441-464, 2021 | 166 | 2021 |
Novel insights into the complex pharmacokinetics of voriconazole: a review of its metabolism J Schulz, F Kluwe, G Mikus, R Michelet, C Kloft Drug metabolism reviews 51 (3), 247-265, 2019 | 59 | 2019 |
Perspectives on model‐informed precision dosing in the digital health era: challenges, opportunities, and recommendations F Kluwe, R Michelet, A Mueller‐Schoell, C Maier, L Klopp‐Schulze, ... Clinical Pharmacology & Therapeutics 109 (1), 29-36, 2021 | 49 | 2021 |
Physiologically based pharmacokinetic predictions of tramadol exposure throughout pediatric life: an analysis of the different clearance contributors with emphasis on CYP2D6 … H T’jollyn, J Snoeys, A Vermeulen, R Michelet, F Cuyckens, G Mannens, ... The AAPS journal 17, 1376-1387, 2015 | 45 | 2015 |
PBPK in preterm and term neonates: a review R Michelet, JV Bocxlaer, A Vermeulen Current pharmaceutical design 23 (38), 5943-5954, 2017 | 34 | 2017 |
The use of PBPK modeling across the pediatric age range using propofol as a case R Michelet, J Van Bocxlaer, K Allegaert, A Vermeulen Journal of Pharmacokinetics and Pharmacodynamics 45, 765-785, 2018 | 32 | 2018 |
Pharmacokinetic/pharmacodynamic evaluation of hydrocortisone therapy in pediatric patients with congenital adrenal hyperplasia J Melin, ZP Parra-Guillen, R Michelet, T Truong, W Huisinga, N Hartung, ... The Journal of Clinical Endocrinology & Metabolism 105 (4), e1729-e1740, 2020 | 28 | 2020 |
Early survival prediction framework in CD19-specific CAR-T cell immunotherapy using a quantitative systems pharmacology model A Mueller-Schoell, N Puebla-Osorio, R Michelet, MR Green, A Künkele, ... Cancers 13 (11), 2782, 2021 | 27 | 2021 |
Obesity alters endoxifen plasma levels in young breast cancer patients: a pharmacometric simulation approach A Mueller‐Schoell, L Klopp‐Schulze, W Schroth, T Mürdter, R Michelet, ... Clinical pharmacology & therapeutics 108 (3), 661-670, 2020 | 23 | 2020 |
Pediatric pharmacology of desmopressin in children with enuresis: a comprehensive review E Gasthuys, L Dossche, R Michelet, JP Nørgaard, M Devreese, ... Pediatric Drugs 22 (4), 369-383, 2020 | 23 | 2020 |
Effects of food and pharmaceutical formulation on desmopressin pharmacokinetics in children R Michelet, L Dossche, P De Bruyne, P Colin, K Boussery, J Vande Walle, ... Clinical pharmacokinetics 55, 1159-1170, 2016 | 22 | 2016 |
Paediatric population pharmacokinetic modelling to assess hydrocortisone replacement dosing regimens in young children R Michelet, J Melin, ZP Parra-Guillen, U Neumann, JM Whitaker, ... European Journal of Endocrinology 183 (4), 357-368, 2020 | 16 | 2020 |
Quantification of microdialysis related variability in humans: clinical trial design recommendations D Busse, P Simon, R Michelet, L Ehmann, F Mehner, C Dorn, A Kratzer, ... European Journal of Pharmaceutical Sciences 157, 105607, 2021 | 15 | 2021 |
Physiologically-based pharmacokinetic model for ciprofloxacin in children with complicated urinary tract infection V Balbas-Martinez, R Michelet, AN Edginton, K Meesters, IF Trocóniz, ... European Journal of Pharmaceutical Sciences 128, 171-179, 2019 | 15 | 2019 |
A rapid, simple and sensitive liquid chromatography tandem mass spectrometry assay to determine amoxicillin concentrations in biological matrix of little volume S Franck, T Fuhrmann-Selter, JF Joseph, R Michelet, F Casilag, JC Sirard, ... Talanta 201, 253-258, 2019 | 14 | 2019 |
Results of a multicenter population pharmacokinetic study of ciprofloxacin in children with complicated urinary tract infection K Meesters, R Michelet, R Mauel, A Raes, J Van Bocxlaer, J Vande Walle, ... Antimicrobial Agents and Chemotherapy 62 (9), 10.1128/aac. 00517-18, 2018 | 14 | 2018 |
Which analysis approach is adequate to leverage clinical microdialysis data? A quantitative comparison to investigate exposure and reponse exemplified by levofloxacin D Busse, A Schaeftlein, A Solms, L Ilia, R Michelet, M Zeitlinger, ... Pharmaceutical Research 38, 381-395, 2021 | 12 | 2021 |
Claiming desmopressin therapeutic equivalence in children requires pediatric data: a population PKPD analysis R Michelet, L Dossche, C Van Herzeele, J Van Bocxlaer, A Vermeulen, ... European journal of clinical pharmacology 74, 297-305, 2018 | 10 | 2018 |
Rationale of a lower dexamethasone dose in prenatal congenital adrenal hyperplasia therapy based on pharmacokinetic modelling V Stachanow, U Neumann, O Blankenstein, U Fuhr, W Huisinga, ... European Journal of Endocrinology 185 (3), 365-374, 2021 | 8 | 2021 |
Desmopressin oral lyophilisate in young children: new insights in pharmacokinetics and pharmacodynamics L Dossche, R Michelet, P De Bruyne, C Van Herzeele, E Gasthuys, ... Archives of disease in childhood 106 (6), 597-602, 2021 | 8 | 2021 |