Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models F Demontis, R Piccirillo, AL Goldberg, N Perrimon Disease models & mechanisms 6 (6), 1339-1352, 2013 | 297 | 2013 |
Muscle wasting in aged, sarcopenic rats is associated with enhanced activity of the ubiquitin proteasome pathway M Altun, HC Besche, HS Overkleeft, R Piccirillo, MJ Edelmann, ... Journal of Biological Chemistry 285 (51), 39597-39608, 2010 | 259 | 2010 |
The influence of skeletal muscle on systemic aging and lifespan F Demontis, R Piccirillo, AL Goldberg, N Perrimon Aging cell 12 (6), 943-949, 2013 | 220 | 2013 |
Mechanisms of muscle growth and atrophy in mammals and Drosophila R Piccirillo, F Demontis, N Perrimon, AL Goldberg Developmental Dynamics 243 (2), 201-215, 2014 | 149 | 2014 |
Exercise-induced myokines with therapeutic potential for muscle wasting R Piccirillo Frontiers in physiology 10, 287, 2019 | 133 | 2019 |
The ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cells I Palmisano, P Bagnato, A Palmigiano, G Innamorati, G Rotondo, ... Human molecular genetics 17 (22), 3487-3501, 2008 | 100 | 2008 |
The p97/VCP ATPase is critical in muscle atrophy and the accelerated degradation of muscle proteins R Piccirillo, AL Goldberg The EMBO journal 31 (15), 3334-3350, 2012 | 85 | 2012 |
Localization to mature melanosomes by virtue of cytoplasmic dileucine motifs is required for human OCA2 function A Sitaram, R Piccirillo, I Palmisano, DC Harper, EC Dell'Angelica, ... Molecular biology of the cell 20 (5), 1464-1477, 2009 | 83 | 2009 |
Musclin, a myokine induced by aerobic exercise, retards muscle atrophy during cancer cachexia in mice AD Re Cecconi, M Forti, M Chiappa, Z Zhu, LV Zingman, L Cervo, ... Cancers 11 (10), 1541, 2019 | 62 | 2019 |
The melanosomal/lysosomal protein OA1 has properties of a G protein‐coupled receptor G Innamorati, R Piccirillo, P Bagnato, I Palmisano, MV Schiaffino Pigment cell research 19 (2), 125-135, 2006 | 60 | 2006 |
An unconventional dileucine-based motif and a novel cytosolic motif are required for the lysosomal and melanosomal targeting of OA1 R Piccirillo, I Palmisano, G Innamorati, P Bagnato, D Altimare, ... Journal of cell science 119 (10), 2003-2014, 2006 | 54 | 2006 |
Amino acid starvation induces reactivation of silenced transgenes and latent HIV-1 provirus via down-regulation of histone deacetylase 4 (HDAC4) I Palmisano, G Della Chiara, RL D’Ambrosio, C Huichalaf, P Brambilla, ... Proceedings of the National Academy of Sciences 109 (34), E2284-E2293, 2012 | 53 | 2012 |
Bioreducible hydrophobin-stabilized supraparticles for selective intracellular release D Maiolo, C Pigliacelli, P Sánchez Moreno, MB Violatto, L Talamini, ... ACS nano 11 (9), 9413-9423, 2017 | 51 | 2017 |
Sunitinib prevents cachexia and prolongs survival of mice bearing renal cancer by restraining STAT3 and MuRF-1 activation in muscle F Pretto, C Ghilardi, M Moschetta, A Bassi, A Rovida, V Scarlato, ... 25460504, 2014 | 45 | 2014 |
Activation of the SDF1/CXCR4 pathway retards muscle atrophy during cancer cachexia GB Martinelli, D Olivari, AD Re Cecconi, L Talamini, L Ottoboni, ... Oncogene 35 (48), 6212-6222, 2016 | 36 | 2016 |
Cathepsins L and Z are critical in degrading polyglutamine-containing proteins within lysosomes N Bhutani, R Piccirillo, R Hourez, P Venkatraman, AL Goldberg Journal of Biological Chemistry 287 (21), 17471-17482, 2012 | 35 | 2012 |
Oxidation of HMGB1 is a dynamically regulated process in physiological and pathological conditions M Ferrara, G Chialli, LM Ferreira, E Ruggieri, G Careccia, A Preti, ... Frontiers in immunology 11, 1122, 2020 | 34 | 2020 |
Nutraceuticals and exercise against muscle wasting during cancer cachexia G Aquila, AD Re Cecconi, JJ Brault, O Corli, R Piccirillo Cells 9 (12), 2536, 2020 | 33 | 2020 |
Expression of OA1 limits the fusion of a subset of MVBs with lysosomes–a mechanism potentially involved in the initial biogenesis of melanosomes T Burgoyne, R Jolly, B Martin-Martin, MC Seabra, R Piccirillo, ... Journal of Cell Science 126 (22), 5143-5152, 2013 | 33 | 2013 |
The ubiquitin ligase tripartite-motif-protein 32 is induced in Duchenne muscular dystrophy S Assereto, R Piccirillo, S Baratto, P Scudieri, C Fiorillo, M Massacesi, ... Laboratory investigation 96 (8), 862-871, 2016 | 21 | 2016 |