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Jianhang Jia
Jianhang Jia
Professor of Biochemistry, University of Kentucky College of Medicine
在 uky.edu 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis
J Jia, W Zhang, B Wang, R Trinko, J Jiang
Genes & development 17 (20), 2514-2519, 2003
4602003
Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I
J Jia, C Tong, B Wang, L Luo, J Jiang
Nature 432 (7020), 1045-1050, 2004
3852004
Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus
J Jia, K Amanai, G Wang, J Tang, B Wang, J Jiang
Nature 416 (6880), 548-552, 2002
3672002
An obligatory role for neurotensin in high-fat-diet-induced obesity
J Li, J Song, YY Zaytseva, Y Liu, P Rychahou, K Jiang, ME Starr, JT Kim, ...
Nature 533 (7603), 411-415, 2016
2542016
Nuclear localization sequence of FUS and induction of stress granules by ALS mutants
J Gal, J Zhang, DM Kwinter, J Zhai, H Jia, J Jia, H Zhu
Neurobiology of aging 32 (12), 2323. e27-2323. e40, 2011
2472011
Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened
Y Chen, N Sasai, G Ma, T Yue, J Jia, J Briscoe, J Jiang
PLoS biology 9 (6), e1001083, 2011
2392011
Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail
J Jia, C Tong, J Jiang
Genes & development 17 (21), 2709-2720, 2003
2182003
Hedgehog-regulated Costal2-kinase complexes control phosphorylation and proteolytic processing of Cubitus interruptus
W Zhang, Y Zhao, C Tong, G Wang, B Wang, J Jia, J Jiang
Developmental cell 8 (2), 267-278, 2005
2132005
Phosphorylation by double-time/CKIε and CKIα targets cubitus interruptus for Slimb/β-TRCP-mediated proteolytic processing
J Jia, L Zhang, Q Zhang, C Tong, B Wang, F Hou, K Amanai, J Jiang
Developmental cell 9 (6), 819-830, 2005
1822005
USP8 promotes smoothened signaling by preventing its ubiquitination and changing its subcellular localization
R Xia, H Jia, J Fan, Y Liu, J Jia
PLoS biology 10 (1), e1001238, 2012
1522012
PR55α, a regulatory subunit of PP2A, specifically regulates PP2A-mediated β-catenin dephosphorylation
W Zhang, J Yang, Y Liu, X Chen, T Yu, J Jia, C Liu
Journal of Biological Chemistry 284 (34), 22649-22656, 2009
1522009
Decoding the Hedgehog signal in animal development
J Jia, J Jiang
Cellular and Molecular Life Sciences CMLS 63, 1249-1265, 2006
1402006
Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS
R Xia, Y Liu, L Yang, J Gal, H Zhu, J Jia
Molecular neurodegeneration 7, 1-17, 2012
1242012
G protein-coupled receptor kinase 2 promotes high-level Hedgehog signaling by regulating the active state of Smo through kinase-dependent and kinase-independent mechanisms in …
Y Chen, S Li, C Tong, Y Zhao, B Wang, Y Liu, J Jia, J Jiang
Genes & development 24 (18), 2054-2067, 2010
1132010
Casein kinase 2 promotes Hedgehog signaling by regulating both smoothened and Cubitus interruptus
H Jia, Y Liu, R Xia, C Tong, T Yue, J Jiang, J Jia
Journal Of Biological Chemistry 285 (48), 37218-37226, 2010
1092010
PPM1A regulates antiviral signaling by antagonizing TBK1-mediated STING phosphorylation and aggregation
Z Li, G Liu, L Sun, Y Teng, X Guo, J Jia, J Sha, X Yang, D Chen, Q Sun
PLoS pathogens 11 (3), e1004783, 2015
1082015
PP4 and PP2A regulate Hedgehog signaling by controlling Smo and Ci phosphorylation
H Jia, Y Liu, W Yan, J Jia
Oxford University Press for The Company of Biologists Limited 136 (2), 307-316, 2009
1012009
Deubiquitinase USP47/UBP64E regulates β-catenin ubiquitination and degradation and plays a positive role in Wnt signaling
J Shi, Y Liu, X Xu, W Zhang, T Yu, J Jia, C Liu
Molecular and cellular biology 35 (19), 3301-3311, 2015
972015
The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation
Q Shi, S Li, J Jia, J Jiang
Development 138 (19), 4219-4231, 2011
752011
Fused–Costal2 protein complex regulates Hedgehog-induced Smo phosphorylation and cell-surface accumulation
Y Liu, X Cao, J Jiang, J Jia
Genes & development 21 (15), 1949-1963, 2007
732007
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