The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis J Jia, W Zhang, B Wang, R Trinko, J Jiang Genes & development 17 (20), 2514-2519, 2003 | 460 | 2003 |
Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I J Jia, C Tong, B Wang, L Luo, J Jiang Nature 432 (7020), 1045-1050, 2004 | 385 | 2004 |
Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus J Jia, K Amanai, G Wang, J Tang, B Wang, J Jiang Nature 416 (6880), 548-552, 2002 | 367 | 2002 |
An obligatory role for neurotensin in high-fat-diet-induced obesity J Li, J Song, YY Zaytseva, Y Liu, P Rychahou, K Jiang, ME Starr, JT Kim, ... Nature 533 (7603), 411-415, 2016 | 254 | 2016 |
Nuclear localization sequence of FUS and induction of stress granules by ALS mutants J Gal, J Zhang, DM Kwinter, J Zhai, H Jia, J Jia, H Zhu Neurobiology of aging 32 (12), 2323. e27-2323. e40, 2011 | 247 | 2011 |
Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened Y Chen, N Sasai, G Ma, T Yue, J Jia, J Briscoe, J Jiang PLoS biology 9 (6), e1001083, 2011 | 239 | 2011 |
Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail J Jia, C Tong, J Jiang Genes & development 17 (21), 2709-2720, 2003 | 218 | 2003 |
Hedgehog-regulated Costal2-kinase complexes control phosphorylation and proteolytic processing of Cubitus interruptus W Zhang, Y Zhao, C Tong, G Wang, B Wang, J Jia, J Jiang Developmental cell 8 (2), 267-278, 2005 | 213 | 2005 |
Phosphorylation by double-time/CKIε and CKIα targets cubitus interruptus for Slimb/β-TRCP-mediated proteolytic processing J Jia, L Zhang, Q Zhang, C Tong, B Wang, F Hou, K Amanai, J Jiang Developmental cell 9 (6), 819-830, 2005 | 182 | 2005 |
USP8 promotes smoothened signaling by preventing its ubiquitination and changing its subcellular localization R Xia, H Jia, J Fan, Y Liu, J Jia PLoS biology 10 (1), e1001238, 2012 | 152 | 2012 |
PR55α, a regulatory subunit of PP2A, specifically regulates PP2A-mediated β-catenin dephosphorylation W Zhang, J Yang, Y Liu, X Chen, T Yu, J Jia, C Liu Journal of Biological Chemistry 284 (34), 22649-22656, 2009 | 152 | 2009 |
Decoding the Hedgehog signal in animal development J Jia, J Jiang Cellular and Molecular Life Sciences CMLS 63, 1249-1265, 2006 | 140 | 2006 |
Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS R Xia, Y Liu, L Yang, J Gal, H Zhu, J Jia Molecular neurodegeneration 7, 1-17, 2012 | 124 | 2012 |
G protein-coupled receptor kinase 2 promotes high-level Hedgehog signaling by regulating the active state of Smo through kinase-dependent and kinase-independent mechanisms in … Y Chen, S Li, C Tong, Y Zhao, B Wang, Y Liu, J Jia, J Jiang Genes & development 24 (18), 2054-2067, 2010 | 113 | 2010 |
Casein kinase 2 promotes Hedgehog signaling by regulating both smoothened and Cubitus interruptus H Jia, Y Liu, R Xia, C Tong, T Yue, J Jiang, J Jia Journal Of Biological Chemistry 285 (48), 37218-37226, 2010 | 109 | 2010 |
PPM1A regulates antiviral signaling by antagonizing TBK1-mediated STING phosphorylation and aggregation Z Li, G Liu, L Sun, Y Teng, X Guo, J Jia, J Sha, X Yang, D Chen, Q Sun PLoS pathogens 11 (3), e1004783, 2015 | 108 | 2015 |
PP4 and PP2A regulate Hedgehog signaling by controlling Smo and Ci phosphorylation H Jia, Y Liu, W Yan, J Jia Oxford University Press for The Company of Biologists Limited 136 (2), 307-316, 2009 | 101 | 2009 |
Deubiquitinase USP47/UBP64E regulates β-catenin ubiquitination and degradation and plays a positive role in Wnt signaling J Shi, Y Liu, X Xu, W Zhang, T Yu, J Jia, C Liu Molecular and cellular biology 35 (19), 3301-3311, 2015 | 97 | 2015 |
The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation Q Shi, S Li, J Jia, J Jiang Development 138 (19), 4219-4231, 2011 | 75 | 2011 |
Fused–Costal2 protein complex regulates Hedgehog-induced Smo phosphorylation and cell-surface accumulation Y Liu, X Cao, J Jiang, J Jia Genes & development 21 (15), 1949-1963, 2007 | 73 | 2007 |