Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production A Merovci, C Solis-Herrera, G Daniele, R Eldor, TV Fiorentino, D Tripathy, ... The Journal of clinical investigation 124 (2), 509-514, 2014 | 870 | 2014 |
Renal, metabolic and cardiovascular considerations of SGLT2 inhibition RA DeFronzo, L Norton, M Abdul-Ghani Nature Reviews Nephrology 13 (1), 11-26, 2017 | 545 | 2017 |
Role of sodium-glucose cotransporter 2 (SGLT 2) inhibitors in the treatment of type 2 diabetes MA Abdul-Ghani, L Norton, RA DeFronzo Endocrine reviews 32 (4), 515-531, 2011 | 501 | 2011 |
Novel hypothesis to explain why SGLT2 inhibitors inhibit only 30–50% of filtered glucose load in humans MA Abdul-Ghani, RA DeFronzo, L Norton Diabetes 62 (10), 3324-3328, 2013 | 257 | 2013 |
Dapagliflozin enhances fat oxidation and ketone production in patients with type 2 diabetes G Daniele, J Xiong, C Solis-Herrera, A Merovci, R Eldor, D Tripathy, ... Diabetes care 39 (11), 2036-2041, 2016 | 211 | 2016 |
Renal sodium-glucose cotransporter inhibition in the management of type 2 diabetes mellitus MA Abdul-Ghani, L Norton, RA DeFronzo American Journal of Physiology-Renal Physiology 309 (11), F889-F900, 2015 | 154 | 2015 |
Distinct β-cell defects in impaired fasting glucose and impaired glucose tolerance M Kanat, A Mari, L Norton, D Winnier, RA DeFronzo, C Jenkinson, ... Diabetes 61 (2), 447-453, 2012 | 153 | 2012 |
Efficacy and safety of SGLT2 inhibitors in the treatment of type 2 diabetes mellitus MA Abdul-Ghani, L Norton, RA DeFronzo Current diabetes reports 12, 230-238, 2012 | 152 | 2012 |
The diabetes gene and Wnt pathway effector TCF7L2 regulates adipocyte development and function X Chen, I Ayala, C Shannon, M Fourcaudot, NK Acharya, CP Jenkinson, ... Diabetes 67 (4), 554-568, 2018 | 117 | 2018 |
Insulin: The master regulator of glucose metabolism L Norton, C Shannon, A Gastaldelli, RA DeFronzo Metabolism 129, 155142, 2022 | 116 | 2022 |
Lactate elicits ER-mitochondrial Mg2+ dynamics to integrate cellular metabolism CC Daw, K Ramachandran, BT Enslow, S Maity, B Bursic, MJ Novello, ... Cell 183 (2), 474-489. e17, 2020 | 103 | 2020 |
High-fat/low-carbohydrate diet reduces insulin-stimulated carbohydrate oxidation but stimulates nonoxidative glucose disposal in humans: An important role for skeletal muscle … K Chokkalingam, K Jewell, L Norton, J Littlewood, LJC Van Loon, ... The Journal of Clinical Endocrinology & Metabolism 92 (1), 284-292, 2007 | 102 | 2007 |
Chromatin occupancy of transcription factor 7-like 2 (TCF7L2) and its role in hepatic glucose metabolism L Norton, M Fourcaudot, MA Abdul-Ghani, D Winnier, FF Mehta, ... Diabetologia 54, 3132-3142, 2011 | 95 | 2011 |
Sodium‐glucose co‐transporter (SGLT) and glucose transporter (GLUT) expression in the kidney of type 2 diabetic subjects L Norton, CE Shannon, M Fourcaudot, C Hu, N Wang, W Ren, J Song, ... Diabetes, Obesity and Metabolism 19 (9), 1322-1326, 2017 | 88 | 2017 |
Elevated free fatty acids attenuate the insulin-induced suppression of PDK4 gene expression in human skeletal muscle: potential role of intramuscular long-chain acyl-coenzyme A K Tsintzas, K Chokkalingam, K Jewell, L Norton, IA Macdonald, ... The Journal of Clinical Endocrinology & Metabolism 92 (10), 3967-3972, 2007 | 82 | 2007 |
Impaired early-but not late-phase insulin secretion in subjects with impaired fasting glucose M Kanat, L Norton, D Winnier, C Jenkinson, RA DeFronzo, ... Acta diabetologica 48, 209-217, 2011 | 81 | 2011 |
FGF21 is an insulin-dependent postprandial hormone in adult humans RJ Samms, JE Lewis, L Norton, FB Stephens, CJ Gaffney, T Butterfield, ... The Journal of Clinical Endocrinology & Metabolism 102 (10), 3806-3813, 2017 | 79 | 2017 |
The relationship between β-cell function and glycated hemoglobin: results from the veterans administration genetic epidemiology study M Kanat, D Winnier, L Norton, N Arar, C Jenkinson, RA DeFronzo, ... Diabetes care 34 (4), 1006-1010, 2011 | 76 | 2011 |
Empagliflozin and kinetics of renal glucose transport in healthy individuals and individuals with type 2 diabetes H Al-Jobori, G Daniele, E Cersosimo, C Triplitt, R Mehta, L Norton, ... Diabetes 66 (7), 1999-2006, 2017 | 72 | 2017 |
Blockade of MCU-mediated Ca2+ uptake perturbs lipid metabolism via PP4-dependent AMPK dephosphorylation D Tomar, F Jaña, Z Dong, WJ Quinn, P Jadiya, SL Breves, CC Daw, ... Cell reports 26 (13), 3709-3725. e7, 2019 | 67 | 2019 |