Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2 J Nangalia, CE Massie, EJ Baxter, FL Nice, G Gundem, DC Wedge, ... New England Journal of Medicine 369 (25), 2391-2405, 2013 | 2172 | 2013 |
Endoplasmic Reticulum (ER) Mannosidase I Is Compartmentalized and Required for N-Glycan Trimming to Man5–6GlcNAc2 in Glycoprotein ER-associated … E Avezov, Z Frenkel, M Ehrlich, A Herscovics, GZ Lederkremer Molecular biology of the cell 19 (1), 216-225, 2008 | 168 | 2008 |
An optical technique for mapping microviscosity dynamics in cellular organelles JE Chambers, M Kubánková, RG Huber, I López-Duarte, E Avezov, ... Acs Nano 12 (5), 4398-4407, 2018 | 143 | 2018 |
Lifetime imaging of a fluorescent protein sensor reveals surprising stability of ER thiol redox E Avezov, BCS Cross, GS Kaminski Schierle, M Winters, HP Harding, ... Journal of Cell Biology 201 (2), 337-349, 2013 | 104 | 2013 |
Single particle trajectories reveal active endoplasmic reticulum luminal flow D Holcman, P Parutto, JE Chambers, M Fantham, LJ Young, SJ Marciniak, ... Nature cell biology 20 (10), 1118-1125, 2018 | 93 | 2018 |
PERK-dependent compartmentalization of ERAD and unfolded protein response machineries during ER stress M Kondratyev, E Avezov, M Shenkman, B Groisman, GZ Lederkremer Experimental cell research 313 (16), 3395-3407, 2007 | 92 | 2007 |
Fat mass and obesity-related (FTO) shuttles between the nucleus and cytoplasm P Gulati, E Avezov, M Ma, R Antrobus, P Lehner, S O’Rahilly, GSH Yeo Bioscience reports 34 (5), e00144, 2014 | 88 | 2014 |
Intact protein folding in the glutathione-depleted endoplasmic reticulum implicates alternative protein thiol reductants S Tsunoda, E Avezov, A Zyryanova, T Konno, L Mendes-Silva, ... Elife 3, e03421, 2014 | 84 | 2014 |
The structure and global distribution of the endoplasmic reticulum network are actively regulated by lysosomes M Lu, FW van Tartwijk, JQ Lin, W Nijenhuis, P Parutto, M Fantham, ... Science advances 6 (51), eabc7209, 2020 | 81 | 2020 |
Intracellular Sources of ROS/H2O2 in Health and Neurodegeneration: Spotlight on Endoplasmic Reticulum T Konno, EP Melo, JE Chambers, E Avezov Cells 10 (2), 233, 2021 | 80 | 2021 |
Physiological modulation of BiP activity by trans-protomer engagement of the interdomain linker S Preissler, JE Chambers, A Crespillo-Casado, E Avezov, E Miranda, ... Elife 4, e08961, 2015 | 78 | 2015 |
ERO1-independent production of H2O2 within the endoplasmic reticulum fuels Prdx4-mediated oxidative protein folding T Konno, E Pinho Melo, C Lopes, I Mehmeti, S Lenzen, D Ron, E Avezov Journal of Cell Biology 211 (2), 253-259, 2015 | 69 | 2015 |
A shared endoplasmic reticulum-associated degradation pathway involving the EDEM1 protein for glycosylated and nonglycosylated proteins M Shenkman, B Groisman, E Ron, E Avezov, LM Hendershot, ... Journal of Biological Chemistry 288 (4), 2167-2178, 2013 | 69 | 2013 |
A novel signalling screen demonstrates that CALR mutations activate essential MAPK signalling and facilitate megakaryocyte differentiation K Kollmann, W Warsch, C Gonzalez-Arias, FL Nice, E Avezov, J Milburn, ... Leukemia 31 (4), 934-944, 2017 | 62 | 2017 |
ER-resident antioxidative GPx7 and GPx8 enzyme isoforms protect insulin-secreting INS-1E β-cells against lipotoxicity by improving the ER antioxidative capacity I Mehmeti, S Lortz, E Avezov, A Jörns, S Lenzen Free Radical Biology and Medicine 112, 121-130, 2017 | 59 | 2017 |
TriPer, an optical probe tuned to the endoplasmic reticulum tracks changes in luminal H2O2 EP Melo, C Lopes, P Gollwitzer, S Lortz, S Lenzen, I Mehmeti, ... BMC biology 15, 1-15, 2017 | 49 | 2017 |
Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum E Avezov, T Konno, A Zyryanova, W Chen, R Laine, A Crespillo-Casado, ... BMC biology 13, 1-15, 2015 | 47 | 2015 |
Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models AS Mukadam, LVC Miller, AE Smith, M Vaysburd, SA Sakya, S Sanford, ... Science 379 (6639), 1336-1341, 2023 | 28 | 2023 |
A method to quantify FRET stoichiometry with phasor plot analysis and acceptor lifetime ingrowth WY Chen, E Avezov, SC Schlachter, F Gielen, RF Laine, HP Harding, ... Biophysical journal 108 (5), 999-1002, 2015 | 24 | 2015 |
Mannosidase IA is in quality control vesicles and participates in glycoprotein targeting to ERAD N Ogen-Shtern, E Avezov, M Shenkman, R Benyair, GZ Lederkremer Journal of molecular biology 428 (16), 3194-3205, 2016 | 23 | 2016 |