Concurrent, but not sequential, PD-1 blockade with a DNA vaccine elicits anti-tumor responses in patients with metastatic, castration-resistant prostate cancer DG McNeel, JC Eickhoff, E Wargowski, C Zahm, MJ Staab, J Straus, G Liu Oncotarget 9 (39), 25586, 2018 | 79 | 2018 |
Mice expressing activated PI3K rapidly develop advanced colon cancer AA Leystra, DA Deming, CD Zahm, M Farhoud, TJP Olson, JN Hadac, ... Cancer research 72 (12), 2931-2936, 2012 | 79 | 2012 |
Vaccination with High-Affinity Epitopes Impairs Antitumor Efficacy by Increasing PD-1 Expression on CD8+ T Cells CD Zahm, VT Colluru, DG McNeel Cancer immunology research 5 (8), 630-641, 2017 | 62 | 2017 |
90Y-NM600 targeted radionuclide therapy induces immunologic memory in syngeneic models of T-cell Non-Hodgkin’s Lymphoma R Hernandez, KL Walker, JJ Grudzinski, E Aluicio-Sarduy, R Patel, ... Communications biology 2 (1), 79, 2019 | 54 | 2019 |
DNA vaccines for prostate cancer CD Zahm, VT Colluru, DG McNeel Pharmacology & therapeutics 174, 27-42, 2017 | 53 | 2017 |
Antibody and fragment-based PET imaging of CTLA-4+ T-cells in humanized mouse models EB Ehlerding, HJ Lee, D Jiang, CA Ferreira, CD Zahm, P Huang, ... American journal of cancer research 9 (1), 53, 2019 | 50 | 2019 |
TLR Stimulation during T-cell Activation Lowers PD-1 Expression on CD8+ T Cells CD Zahm, VT Colluru, SJ McIlwain, IM Ong, DG McNeel Cancer immunology research 6 (11), 1364-1374, 2018 | 48 | 2018 |
Transformation of epithelial cells through recruitment leads to polyclonal intestinal tumors AT Thliveris, B Schwefel, L Clipson, L Plesh, CD Zahm, AA Leystra, ... Proceedings of the National Academy of Sciences 110 (28), 11523-11528, 2013 | 32 | 2013 |
PD-1 and LAG-3 blockade improve anti-tumor vaccine efficacy CD Zahm, JE Moseman, LE Delmastro, D G. Mcneel Oncoimmunology 10 (1), 1912892, 2021 | 29 | 2021 |
FLT PET/CT imaging of metastatic prostate cancer patients treated with pTVG-HP DNA vaccine and pembrolizumab M Scarpelli, C Zahm, S Perlman, DG McNeel, R Jeraj, G Liu Journal for immunotherapy of cancer 7, 1-13, 2019 | 26 | 2019 |
Mini-intronic plasmid vaccination elicits tolerant LAG3+ CD8+ T cells and inferior antitumor responses VT Colluru, CD Zahm, DG McNeel Oncoimmunology 5 (10), e1223002, 2016 | 24 | 2016 |
Treatment combinations with DNA vaccines for the treatment of metastatic castration-resistant prostate cancer (mCRPC) M Gamat-Huber, D Jeon, LE Johnson, JE Moseman, A Muralidhar, ... Cancers 12 (10), 2831, 2020 | 17 | 2020 |
Dynamic tumor growth patterns in a novel murine model of colorectal cancer TJ Paul Olson, JN Hadac, CK Sievers, AA Leystra, DA Deming, CD Zahm, ... Cancer Prevention Research 7 (1), 105-113, 2014 | 16 | 2014 |
Clonal structure of carcinogen-induced intestinal tumors in mice AT Thliveris, L Clipson, A White, J Waggoner, L Plesh, BL Skinner, ... Cancer Prevention Research 4 (6), 916-923, 2011 | 14 | 2011 |
Vaccination with high-affinity epitopes impairs antitumor efficacy by increasing PD-1 expression on CD8+ T cells. Cancer Immunol. Res. 2017; 5: 630–641. doi: 10.1158/2326-6066 CD Zahm, VT Colluru, DG McNeel CIR-16-0374, 0 | 13 | |
Advanced intestinal cancers often maintain a multi-ancestral architecture CD Zahm, JM Szulczewski, AA Leystra, TJ Paul Olson, L Clipson, ... PLoS One 11 (2), e0150170, 2016 | 7 | 2016 |
TLR Stimulation during T-cell Activation Lowers PD-1 Expression on CD8 (+) T Cells. Cancer Immunol. Res. 2018; 6: 1364–1374. doi: 10.1158/2326-6066 CD Zahm, VT Colluru, SJ McIlwain, IM Ong, DG McNeel CIR-18-0243.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 6 | |
90Y-NM600 targeted radionuclide therapy induces immunologic memory in syngeneic models of T-cell non-Hodgkin's lymphoma. Commun Biol. 2019; 2: 79 R Hernandez, KL Walker, JJ Grudzinski, E Aluicio-Sarduy, R Patel, ... | 4 | 2019 |
Tlr agonists for reducing activation-induced pd-1 expression on t cells and methods of use DG McNeel, CD Zahm US Patent App. 15/838,824, 2018 | 3 | 2018 |
Low-dose TRT reshapes the microenvironment of prostate tumors to potentiate response to immunotherapy R Hernandez, H Potluri, E Aluicio-Sarduy, J Grudzinski, C Massey, ... Journal of Nuclear Medicine 61 (supplement 1), 36-36, 2020 | 2 | 2020 |