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Cheng Fang
Cheng Fang
Associate Director, Blueprint Medicines
在 blueprintmedicines.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Mechanism of photoinduced metal-free atom transfer radical polymerization: experimental and computational studies
X Pan, C Fang, M Fantin, N Malhotra, WY So, LA Peteanu, AA Isse, ...
Journal of the American Chemical Society 138 (7), 2411-2425, 2016
4372016
Ligand–substrate dispersion facilitates the copper-catalyzed hydroamination of unactivated olefins
G Lu, RY Liu, Y Yang, C Fang, DS Lambrecht, SL Buchwald, P Liu
Journal of the American Chemical Society 139 (46), 16548-16555, 2017
2042017
Mechanistically guided predictive models for ligand and initiator effects in copper-catalyzed atom transfer radical polymerization (Cu-ATRP)
C Fang, M Fantin, X Pan, K De Fiebre, ML Coote, K Matyjaszewski, P Liu
Journal of the American Chemical Society 141 (18), 7486-7497, 2019
1142019
Computational study of Rh-catalyzed carboacylation of olefins: ligand-promoted rhodacycle isomerization enables regioselective C–C bond functionalization of benzocyclobutenones
G Lu, C Fang, T Xu, G Dong, P Liu
Journal of the American Chemical Society 137 (25), 8274-8283, 2015
1052015
Targeting colon cancer with the novel STAT3 inhibitor bruceantinol
N Wei, J Li, C Fang, J Chang, V Xirou, NK Syrigos, BJ Marks, E Chu, ...
Oncogene 38 (10), 1676-1687, 2019
812019
Sequence-controlled polymers through entropy-driven ring-opening metathesis polymerization: theory, molecular weight control, and monomer design
JA Nowalk, C Fang, AL Short, RM Weiss, JH Swisher, P Liu, TY Meyer
Journal of the American Chemical Society 141 (14), 5741-5752, 2019
812019
Rhodium‐Catalyzed Enantioselective Radical Addition of CX4 Reagents to Olefins
B Chen, C Fang, P Liu, JM Ready
Angewandte Chemie International Edition 56 (30), 8780-8784, 2017
762017
Synthesis of boriranes by double hydroboration reactions of N-heterocyclic carbene boranes and dimethyl acetylenedicarboxylate
TR McFadden, C Fang, SJ Geib, E Merling, P Liu, DP Curran
Journal of the American Chemical Society 139 (5), 1726-1729, 2017
592017
Chemogenomics knowledgebased polypharmacology analyses of drug abuse related G-protein coupled receptors and their ligands
XQ Xie, L Wang, H Liu, Q Ouyang, C Fang, W Su
Frontiers in pharmacology 5, 3, 2014
342014
Prospective validation of machine learning algorithms for absorption, distribution, metabolism, and excretion prediction: An industrial perspective
C Fang, Y Wang, R Grater, S Kapadnis, C Black, P Trapa, S Sciabola
Journal of Chemical Information and Modeling 63 (11), 3263-3274, 2023
322023
Cis-Selective Metathesis to Enhance the Living Character of Ring-Opening Polymerization: An Approach to Sequenced Copolymers
AL Short, C Fang, JA Nowalk, RM Weiss, P Liu, TY Meyer
ACS Macro Letters 7 (7), 858-862, 2018
282018
Two novel fungal phenolic UDP glycosyltransferases from Absidia coerulea and Rhizopus japonicus
K Xie, X Dou, R Chen, D Chen, C Fang, Z Xiao, J Dai
Applied and environmental microbiology 83 (8), e03103-16, 2017
262017
Receptor-based 3D-QSAR in drug design: methods and applications in kinase studies
C Fang, Z Xiao
Current topics in medicinal chemistry 16 (13), 1463-1477, 2016
252016
Generation and validation of the first predictive pharmacophore model for cyclin-dependent kinase 9 inhibitors
C Fang, Z Xiao, Z Guo
Journal of Molecular Graphics and Modelling 29 (6), 800-808, 2011
202011
Construction of a spirooxindole amide library through nitrile hydrozirconation-acylation-cyclization cascade
MG LaPorte, S Tsegay, KB Hong, C Lu, C Fang, L Wang, XQ Xie, ...
ACS combinatorial science 15 (7), 344-349, 2013
192013
Methylene blue-catalyzed oxidative cleavage of N-carbonylated indoles
K Wu, C Fang, S Kaur, P Liu, T Wang
Synthesis 50 (15), 2897-2907, 2018
182018
β‐Mannosylation through O‐Alkylation of Anomeric Cesium Alkoxides: Mechanistic Studies and Synthesis of the Hexasaccharide Core of Complex Fucosylated N …
S Meng, BR Bhetuwal, H Nguyen, X Qi, C Fang, K Saybolt, X Li, P Liu, ...
European journal of organic chemistry 2020 (15), 2291-2301, 2020
152020
Artificial intelligence–enabled de novo design of novel compounds that are synthesizable
G Bhisetti, C Fang
Artificial Intelligence in Drug Design, 409-419, 2022
112022
Discovery of novel 5-fluoro-N 2, N 4-diphenylpyrimidine-2, 4-diamines as potent inhibitors against CDK2 and CDK9
J Gao*, C Fang*, Z Xiao, L Huang, CH Chen, LT Wang, KH Lee
MedChemComm 6 (3), 444-454, 2015
112015
Polypharmacology analysis of anti-osteoporosis agents and cannabinoid 2 receptor inverse agonists for osteoporosis drug research
C Fang
University of Pittsburgh, 2014
22014
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