| Glioblastoma stem cells: lessons from the tumor hierarchy in a lethal cancer RC Gimple, S Bhargava, D Dixit, JN Rich Genes & development 33 (11-12), 591-609, 2019 | 415 | 2019 |
| Targeting glioma stem cells through combined BMI1 and EZH2 inhibition X Jin, LJY Kim, Q Wu, LC Wallace, BC Prager, T Sanvoranart, RC Gimple, ... Nature medicine 23 (11), 1352-1361, 2017 | 338 | 2017 |
| N6-methyladenine DNA modification in glioblastoma Q Xie, TP Wu, RC Gimple, Z Li, BC Prager, Q Wu, Y Yu, P Wang, Y Wang, ... Cell 175 (5), 1228-1243. e20, 2018 | 258 | 2018 |
| The RNA m6A reader YTHDF2 maintains oncogene expression and is a targetable dependency in glioblastoma stem cells D Dixit, BC Prager, RC Gimple, HX Poh, Y Wang, Q Wu, Z Qiu, RL Kidwell, ... Cancer discovery 11 (2), 480-499, 2021 | 253 | 2021 |
| Functional enhancers shape extrachromosomal oncogene amplifications AR Morton, N Dogan-Artun, ZJ Faber, G MacLeod, CF Bartels, MS Piazza, ... Cell 179 (6), 1330-1341. e13, 2019 | 253 | 2019 |
| Reciprocal signaling between glioblastoma stem cells and differentiated tumor cells promotes malignant progression X Wang, BC Prager, Q Wu, LJY Kim, RC Gimple, Y Shi, K Yang, ... Cell stem cell 22 (4), 514-528. e5, 2018 | 224 | 2018 |
| Targeting glioma stem cell-derived pericytes disrupts the blood-tumor barrier and improves chemotherapeutic efficacy W Zhou, C Chen, Y Shi, Q Wu, RC Gimple, X Fang, Z Huang, K Zhai, ... Cell stem cell 21 (5), 591-603. e4, 2017 | 204 | 2017 |
| Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions M Tang, Q Xie, RC Gimple, Z Zhong, T Tam, J Tian, RL Kidwell, Q Wu, ... Cell research 30 (10), 833-853, 2020 | 200 | 2020 |
| Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling SC Mack, KW Pajtler, L Chavez, K Okonechnikov, KC Bertrand, X Wang, ... Nature 553 (7686), 101-105, 2018 | 197 | 2018 |
| Targeting glioblastoma stem cells through disruption of the circadian clock Z Dong, G Zhang, M Qu, RC Gimple, Q Wu, Z Qiu, BC Prager, X Wang, ... Cancer discovery 9 (11), 1556-1573, 2019 | 194* | 2019 |
| RAS: Striking at the Core of the Oncogenic Circuitry RC Gimple, X Wang Frontiers in oncology 9, 965, 2019 | 173 | 2019 |
| Glioma stem cell–specific superenhancer promotes polyunsaturated fatty-acid synthesis to support EGFR signaling RC Gimple, RL Kidwell, LJY Kim, T Sun, AD Gromovsky, Q Wu, M Wolf, ... Cancer discovery 9 (9), 1248-1267, 2019 | 143 | 2019 |
| Zika virus targets glioblastoma stem cells through a SOX2-integrin αvβ5 axis Z Zhu, P Mesci, JA Bernatchez, RC Gimple, X Wang, ST Schafer, ... Cell stem cell 26 (2), 187-204. e10, 2020 | 142 | 2020 |
| Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells X Wang, K Yang, Q Wu, LJY Kim, AR Morton, RC Gimple, BC Prager, ... Science translational medicine 11 (504), eaau4972, 2019 | 130 | 2019 |
| DNA methylation of the aryl hydrocarbon receptor repressor associations with cigarette smoking and subclinical atherosclerosis LM Reynolds, M Wan, J Ding, JR Taylor, K Lohman, D Su, BD Bennett, ... Circulation: cardiovascular genetics 8 (5), 707-716, 2015 | 127 | 2015 |
| Ibrutinib inactivates BMX-STAT3 in glioma stem cells to impair malignant growth and radioresistance Y Shi, OA Guryanova, W Zhou, C Liu, Z Huang, X Fang, X Wang, C Chen, ... Science translational medicine 10 (443), eaah6816, 2018 | 124 | 2018 |
| Distinct epigenetic effects of tobacco smoking in whole blood and among leukocyte subtypes D Su, X Wang, MR Campbell, DK Porter, GS Pittman, BD Bennett, M Wan, ... PloS one 11 (12), e0166486, 2016 | 119 | 2016 |
| MYC-regulated mevalonate metabolism maintains brain tumor–initiating cells X Wang, Z Huang, Q Wu, BC Prager, SC Mack, K Yang, LJY Kim, ... Cancer research 77 (18), 4947-4960, 2017 | 110 | 2017 |
| Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma SC Mack, I Singh, X Wang, R Hirsch, Q Wu, R Villagomez, JA Bernatchez, ... Journal of Experimental Medicine 216 (5), 1071-1090, 2019 | 102 | 2019 |
| CRISPR screening of CAR T cells and cancer stem cells reveals critical dependencies for cell-based therapies D Wang, BC Prager, RC Gimple, B Aguilar, D Alizadeh, H Tang, D Lv, ... Cancer discovery 11 (5), 1192-1211, 2021 | 99 | 2021 |
