Cancer-associated protein kinase C mutations reveal kinase’s role as tumor suppressor CE Antal, AM Hudson, E Kang, C Zanca, C Wirth, NL Stephenson, ... Cell 160 (3), 489-502, 2015 | 353 | 2015 |
Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring Y Shi, W Gao, NK Lytle, P Huang, X Yuan, AM Dann, M Ridinger-Saison, ... Nature 569 (7754), 131-135, 2019 | 340 | 2019 |
Gain-of-function mutations in protein kinase Cα (PKCα) may promote synaptic defects in Alzheimer’s disease SI Alfonso, JA Callender, B Hooli, CE Antal, K Mullin, MA Sherman, ... Science signaling 9 (427), ra47-ra47, 2016 | 101 | 2016 |
Intramolecular conformational changes optimize protein kinase C signaling CE Antal, JD Violin, MT Kunkel, S Skovsø, AC Newton Chemistry & biology 21 (4), 459-469, 2014 | 83 | 2014 |
Tuning the signalling output of protein kinase C CE Antal, AC Newton Biochemical Society Transactions 42 (6), 1477-1483, 2014 | 77 | 2014 |
Intramolecular C2 domain-mediated autoinhibition of protein kinase C βII CE Antal, JA Callender, AP Kornev, SS Taylor, AC Newton Cell reports 12 (8), 1252-1260, 2015 | 66 | 2015 |
Protein kinase C mechanisms that contribute to cardiac remodelling AC Newton, CE Antal, SF Steinberg Clinical science 130 (17), 1499-1510, 2016 | 64 | 2016 |
The effect of short‐term hypoxic exposure on metabolic gene expression MV Everett, CE Antal, DL Crawford Journal of Experimental Zoology Part A: Ecological Genetics and Physiology …, 2012 | 54 | 2012 |
Spatiotemporal dynamics of phosphorylation in lipid second messenger signaling CE Antal, AC Newton Molecular & Cellular Proteomics 12 (12), 3498-3508, 2013 | 53 | 2013 |
Triptolide targets super-enhancer networks in pancreatic cancer cells and cancer-associated fibroblasts P Noel, S Hussein, S Ng, CE Antal, W Lin, E Rodela, P Delgado, ... Oncogenesis 9 (11), 100, 2020 | 48 | 2020 |
Active site inhibitors protect protein kinase C from dephosphorylation and stabilize its mature form CM Gould, CE Antal, G Reyes, MT Kunkel, RA Adams, A Ziyar, T Riveros, ... Journal of Biological Chemistry 286 (33), 28922-28930, 2011 | 46 | 2011 |
Genomic and epigenomic landscaping defines new therapeutic targets for adenosquamous carcinoma of the pancreas E Lenkiewicz, S Malasi, TL Hogenson, LF Flores, W Barham, WJ Phillips, ... Cancer research 80 (20), 4324-4334, 2020 | 45 | 2020 |
Electrostatic and hydrophobic interactions differentially tune membrane binding kinetics of the C2 domain of protein kinase Cα AM Scott, CE Antal, AC Newton Journal of Biological Chemistry 288 (23), 16905-16915, 2013 | 39 | 2013 |
Protein kinase C fusion proteins are paradoxically loss of function in cancer AAN Van, MT Kunkel, TR Baffi, G Lordén, CE Antal, S Banerjee, ... Journal of Biological Chemistry 296, 2021 | 28 | 2021 |
Euphohelioscopin A is a PKC activator capable of inducing macrophage differentiation L de Lichtervelde, CE Antal, AE Boitano, Y Wang, P Krastel, F Petersen, ... Chemistry & biology 19 (8), 994-1000, 2012 | 10 | 2012 |
Abstract CT165: Phase II open label trial of minnelide™ in patients with chemotherapy refractory metastatic pancreatic cancer D Propper, H Han, DV Hoff, E Borazanci, T Reya, J Ghergurovich, ... Cancer Research 79 (13_Supplement), CT165-CT165, 2019 | 6 | 2019 |
A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer CE Antal, TG Oh, S Aigner, EC Luo, BA Yee, T Campos, H Tiriac, ... Nature communications 14 (1), 5195, 2023 | 3 | 2023 |
Author Correction: Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring Y Shi, W Gao, NK Lytle, P Huang, X Yuan, AM Dann, M Ridinger-Saison, ... Nature 600 (7889), E18, 2021 | 2 | 2021 |
Protein kinase C loss-of-function mutations in cancer reveal role as tumor suppressor CE Antal, AM Hudson, E Kang, C Zanca, C Wirth, NL Stephenson, ... Cancer Research 75 (15_Supplement), 125-125, 2015 | 2 | 2015 |
Prevalence of inactivating protein kinase C mutations in human cancers (1055.2) C Antal, E Kang, N Stephenson, E Trotter, T Hunter, J Brognard, A Newton The FASEB Journal 28, 1055.2, 2014 | 2 | 2014 |