Molecular mechanisms of membrane targeting antibiotics RM Epand, C Walker, RF Epand, NA Magarvey Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (5), 980-987, 2016 | 633 | 2016 |
Isolation and characterization of novel marine-derived actinomycete taxa rich in bioactive metabolites NA Magarvey, JM Keller, V Bernan, M Dworkin, DH Sherman Applied and environmental microbiology 70 (12), 7520-7529, 2004 | 368 | 2004 |
PRISM 3: expanded prediction of natural product chemical structures from microbial genomes MA Skinnider, NJ Merwin, CW Johnston, NA Magarvey Nucleic acids research 45 (W1), W49-W54, 2017 | 337 | 2017 |
Genomes to natural products prediction informatics for secondary metabolomes (PRISM) MA Skinnider, CA Dejong, PN Rees, CW Johnston, H Li, ALH Webster, ... Nucleic acids research 43 (20), 9645-9662, 2015 | 310 | 2015 |
Gold biomineralization by a metallophore from a gold-associated microbe CW Johnston, MA Wyatt, X Li, A Ibrahim, J Shuster, G Southam, ... Nature chemical biology 9 (4), 241-243, 2013 | 277 | 2013 |
Duodenal bacteria from patients with celiac disease and healthy subjects distinctly affect gluten breakdown and immunogenicity A Caminero, HJ Galipeau, JL McCarville, CW Johnston, SP Bernier, ... Gastroenterology 151 (4), 670-683, 2016 | 236 | 2016 |
Lactobacillus reuteri-produced cyclic dipeptides quench agr-mediated expression of toxic shock syndrome toxin-1 in staphylococci J Li, W Wang, SX Xu, NA Magarvey, JK McCormick Proceedings of the National Academy of Sciences 108 (8), 3360-3365, 2011 | 230 | 2011 |
Comprehensive prediction of secondary metabolite structure and biological activity from microbial genome sequences MA Skinnider, CW Johnston, M Gunabalasingam, NJ Merwin, ... Nature communications 11 (1), 6058, 2020 | 220 | 2020 |
Merging the potential of microbial genetics with biological and chemical diversity: an even brighter future for marine natural product drug discovery CE Salomon, NA Magarvey, DH Sherman Natural product reports 21 (1), 105-121, 2004 | 218 | 2004 |
Biosynthetic characterization and chemoenzymatic assembly of the cryptophycins. Potent anticancer agents from Nostoc cyanobionts NA Magarvey, ZQ Beck, T Golakoti, Y Ding, U Huber, TK Hemscheidt, ... ACS chemical biology 1 (12), 766-779, 2006 | 200 | 2006 |
Genomic charting of ribosomally synthesized natural product chemical space facilitates targeted mining MA Skinnider, CW Johnston, RE Edgar, CA Dejong, NJ Merwin, PN Rees, ... Proceedings of the National Academy of Sciences 113 (42), E6343-E6351, 2016 | 164 | 2016 |
Characterization of the cereulide NRPS α-hydroxy acid specifying modules: activation of α-keto acids and chiral reduction on the assembly line NA Magarvey, M Ehling-Schulz, CT Walsh Journal of the American Chemical Society 128 (33), 10698-10699, 2006 | 163 | 2006 |
Polyketide and nonribosomal peptide retro-biosynthesis and global gene cluster matching CA Dejong, GM Chen, H Li, CW Johnston, MR Edwards, PN Rees, ... Nature chemical biology 12 (12), 1007-1014, 2016 | 150 | 2016 |
The gene cluster for chloramphenicol biosynthesis in Streptomyces venezuelae ISP5230 includes novel shikimate pathway homologues and a monomodular non … J He, N Magarvey, M Piraee, LC Vining Microbiology 147 (10), 2817-2829, 2001 | 150 | 2001 |
Staphylococcus aureus nonribosomal peptide secondary metabolites regulate virulence MA Wyatt, W Wang, CM Roux, FC Beasley, DE Heinrichs, PM Dunman, ... Science 329 (5989), 294-296, 2010 | 149 | 2010 |
An automated Genomes-to-Natural Products platform (GNP) for the discovery of modular natural products CW Johnston, MA Skinnider, MA Wyatt, X Li, MRM Ranieri, L Yang, ... Nature communications 6 (1), 8421, 2015 | 135 | 2015 |
Biosynthetic pathway for mannopeptimycins, lipoglycopeptide antibiotics active against drug-resistant gram-positive pathogens NA Magarvey, B Haltli, M He, M Greenstein, JA Hucul Antimicrobial agents and chemotherapy 50 (6), 2167-2177, 2006 | 131 | 2006 |
Assembly and clustering of natural antibiotics guides target identification CW Johnston, MA Skinnider, CA Dejong, PN Rees, GM Chen, CG Walker, ... Nature chemical biology 12 (4), 233-239, 2016 | 108 | 2016 |
DeepRiPP integrates multiomics data to automate discovery of novel ribosomally synthesized natural products NJ Merwin, WK Mousa, CA Dejong, MA Skinnider, MJ Cannon, H Li, ... Proceedings of the National Academy of Sciences 117 (1), 371-380, 2020 | 106 | 2020 |
Dereplicating nonribosomal peptides using an informatic search algorithm for natural products (iSNAP) discovery A Ibrahim, L Yang, C Johnston, X Liu, B Ma, NA Magarvey Proceedings of the National Academy of Sciences 109 (47), 19196-19201, 2012 | 81 | 2012 |