| Targeting of CD44 eradicates human acute myeloid leukemic stem cells L Jin, KJ Hope, Q Zhai, F Smadja-Joffe, JE Dick Nature medicine 12 (10), 1167-1174, 2006 | 1547 | 2006 |
| Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity KJ Hope, L Jin, JE Dick Nature immunology 5 (7), 738-743, 2004 | 1303 | 2004 |
| Modeling the initiation and progression of human acute leukemia in mice F Barabé, JA Kennedy, KJ Hope, JE Dick Science 316 (5824), 600-604, 2007 | 457 | 2007 |
| Concepts of human leukemic development JK Warner, JCY Wang, KJ Hope, L Jin, JE Dick Oncogene 23 (43), 7164-7177, 2004 | 310 | 2004 |
| An RNAi screen identifies Msi2 and Prox1 as having opposite roles in the regulation of hematopoietic stem cell activity KJ Hope, S Cellot, SB Ting, T MacRae, N Mayotte, NN Iscove, ... Cell stem cell 7 (1), 101-113, 2010 | 168 | 2010 |
| Human acute myeloid leukemia stem cells KJ Hope, L Jin, JE Dick Archives of medical research 34 (6), 507-514, 2003 | 139 | 2003 |
| The rational development of CD133-targeting immunotherapies for glioblastoma P Vora, C Venugopal, SK Salim, N Tatari, D Bakhshinyan, M Singh, ... Cell Stem Cell 26 (6), 832-844. e6, 2020 | 137 | 2020 |
| Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells S Rentas, NT Holzapfel, MS Belew, GA Pratt, V Voisin, BT Wilhelm, ... Nature 532 (7600), 508-511, 2016 | 136 | 2016 |
| Nuclear localizing sequences promote nuclear translocation and enhance the radiotoxicity of the anti-CD33 monoclonal antibody HuM195 labeled with 111In in human myeloid … P Chen, J Wang, K Hope, L Jin, J Dick, R Cameron, J Brandwein, ... Journal of Nuclear Medicine 47 (5), 827-836, 2006 | 123 | 2006 |
| Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic Ap2a2 SB Ting, E Deneault, K Hope, S Cellot, J Chagraoui, N Mayotte, JF Dorn, ... Blood, The Journal of the American Society of Hematology 119 (11), 2510-2522, 2012 | 109 | 2012 |
| A role for GPx3 in activity of normal and leukemia stem cells O Herault, KJ Hope, E Deneault, N Mayotte, J Chagraoui, BT Wilhelm, ... Journal of Experimental Medicine 209 (5), 895-901, 2012 | 106 | 2012 |
| OTUD7A regulates neurodevelopmental phenotypes in the 15q13. 3 microdeletion syndrome M Uddin, BK Unda, V Kwan, NT Holzapfel, SH White, L Chalil, ... The American Journal of Human Genetics 102 (2), 278-295, 2018 | 91 | 2018 |
| RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity S Cellot, KJ Hope, J Chagraoui, M Sauvageau, E Deneault, T MacRae, ... Blood, The Journal of the American Society of Hematology 122 (9), 1545-1555, 2013 | 71 | 2013 |
| RNA-seq analysis of 2 closely related leukemia clones that differ in their self-renewal capacity BT Wilhelm, M Briau, P Austin, A Faubert, G Boucher, P Chagnon, K Hope, ... Blood, The Journal of the American Society of Hematology 117 (2), e27-e38, 2011 | 70 | 2011 |
| Very long chain fatty acid metabolism is required in acute myeloid leukemia M Tcheng, A Roma, N Ahmed, RW Smith, P Jayanth, MD Minden, ... Blood, The Journal of the American Society of Hematology 137 (25), 3518-3532, 2021 | 67 | 2021 |
| Clonal interrogation of stem cells K Hope, M Bhatia Nature Methods 8 (Suppl 4), S36-S40, 2011 | 54 | 2011 |
| Aberrant clonal hematopoiesis following lentiviral vector transduction of HSPCs in a rhesus macaque DA Espinoza, X Fan, D Yang, SF Cordes, LL Truitt, KR Calvo, IM Yabe, ... Molecular Therapy 27 (6), 1074-1086, 2019 | 34 | 2019 |
| PLAG1 and USF2 co-regulate expression of Musashi-2 in human hematopoietic stem and progenitor cells MS Belew, S Bhatia, AK Chahi, S Rentas, JS Draper, KJ Hope Stem cell reports 10 (4), 1384-1397, 2018 | 29 | 2018 |
| DIXDC1 phosphorylation and control of dendritic morphology are impaired by rare genetic variants V Kwan, DP Meka, SH White, CL Hung, NT Holzapfel, S Walker, ... Cell reports 17 (7), 1892-1904, 2016 | 29 | 2016 |
| Diminished AHR signaling drives human acute myeloid leukemia stem cell maintenance M Ly, S Rentas, A Vujovic, N Wong, S Moreira, J Xu, N Holzapfel, S Bhatia, ... Cancer Research 79 (22), 5799-5811, 2019 | 27 | 2019 |
