Mesenchymal stem cell-derived extracellular vesicles: toward cell-free therapeutic applications S Rani, AE Ryan, MD Griffin, T Ritter Molecular Therapy 23 (5), 812-823, 2015 | 1087 | 2015 |
Mesenchymal stem cells enhance recovery and repair following ventilator-induced lung injury in the rat GF Curley, M Hayes, B Ansari, G Shaw, A Ryan, F Barry, T O'Brien, ... Thorax 67 (6), 496-501, 2012 | 334 | 2012 |
Anti‐donor immune responses elicited by allogeneic mesenchymal stem cells: what have we learned so far? MD Griffin, AE Ryan, S Alagesan, P Lohan, O Treacy, T Ritter Immunology and cell biology 91 (1), 40-51, 2013 | 294 | 2013 |
Extracellular vesicles as modulators of wound healing J Cabral, AE Ryan, MD Griffin, T Ritter Advanced Drug Delivery Reviews 129, 394-406, 2018 | 145 | 2018 |
Effects of intratracheal mesenchymal stromal cell therapy during recovery and resolution after ventilator-induced lung injury GF Curley, B Ansari, M Hayes, J Devaney, C Masterson, A Ryan, F Barry, ... Anesthesiology 118 (4), 924-932, 2013 | 139 | 2013 |
Anti-donor immune responses elicited by allogeneic mesenchymal stem cells and their extracellular vesicles: are we still learning? P Lohan, O Treacy, MD Griffin, T Ritter, AE Ryan Frontiers in Immunology 8, 1626, 2017 | 129 | 2017 |
Chondrogenic differentiation increases antidonor immune response to allogeneic mesenchymal stem cell transplantation. AE Ryan, P Lohan, L O'Flynn, O Treacy, X Chen, C Coleman, G Shaw, ... Molecular Therapy 22 (3), 655-667, 2014 | 123 | 2014 |
Addressing the “Fas counterattack” controversy: blocking fas ligand expression suppresses tumor immune evasion of colon cancer in vivo AE Ryan, F Shanahan, J O'Connell, AM Houston Cancer research 65 (21), 9817-9823, 2005 | 116 | 2005 |
Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer D Basudhar, SA Glynn, M Greer, V Somasundaram, JH No, DA Scheiblin, ... Proceedings of the National Academy of Sciences 114 (49), 13030-13035, 2017 | 105 | 2017 |
Considerations for treatment duration in responders to immune checkpoint inhibitors TU Marron, AE Ryan, SM Reddy, S Kaczanowska, RH Younis, D Thakkar, ... Journal for immunotherapy of cancer 9 (3), 2021 | 85 | 2021 |
Changes in immunological profile of allogeneic mesenchymal stem cells after differentiation: should we be concerned? P Lohan, CM Coleman, JM Murphy, DM Griffin, T Ritter, AE Ryan Stem Cell Research and Therapy 5 (99), 2014 | 80 | 2014 |
Impact of inducible nitric oxide synthase (iNOS) expression on triple negative breast cancer outcome and activation of EGFR and ERK signaling pathways P Garrido, A Shalaby, EM Walsh, N Keane, M Webber, MM Keane, ... Oncotarget 8 (46), 80568, 2017 | 79 | 2017 |
Immune modulation to improve tissue engineering outcomes for cartilage repair in the osteoarthritic joint N Fahy, E Farrell, T Ritter, AE Ryan, JM Murphy Tissue Engineering Part B: Reviews 21 (1), 55-66, 2015 | 77 | 2015 |
Decoy receptors block TRAIL sensitivity at a supracellular level: the role of stromal cells in controlling tumour TRAIL sensitivity L O'Leary, AM van der Sloot, CR Reis, S Deegan, AE Ryan, SPS Dhami, ... Oncogene 35 (10), 1261-1270, 2016 | 76 | 2016 |
Autophagosomal IκBα degradation plays a role in the long term control of tumor necrosis factor-α-induced nuclear factor-κB (NF-κB) activity A Colleran, A Ryan, A O'Gorman, C Mureau, C Liptrot, P Dockery, ... Journal of Biological Chemistry 286 (26), 22886-22893, 2011 | 76 | 2011 |
Stromal Cell PD-L1 Inhibits CD8+ T-cell Antitumor Immune Responses and Promotes Colon Cancer G O'Malley, O Treacy, K Lynch, SD Naicker, NA Leonard, P Lohan, ... Cancer immunology research 6 (11), 1426-1441, 2018 | 72 | 2018 |
A 3D view of colorectal cancer models in predicting therapeutic responses and resistance E Reidy, NA Leonard, O Treacy, AE Ryan Cancers 13 (2), 227, 2021 | 65 | 2021 |
Mesenchymal stromal cells (MSCs) and colorectal cancer: a troublesome twosome for the anti-tumour immune response? G O'Malley, M Heijltjes, AM Houston, S Rani, T Ritter, LJ Egan, AE Ryan Oncotarget 7 (37), 60752, 2016 | 65 | 2016 |
Mesenchymal stem cell therapy promotes corneal allograft survival in rats by local and systemic immunomodulation O Treacy, L O’Flynn, AE Ryan, M Morcos, P Lohan, S Schu, M Wilk, ... American Journal of Transplantation 14 (9), 2023-2036, 2014 | 62 | 2014 |
Targeting colon cancer cell NF-κB promotes an anti-tumour M1-like macrophage phenotype and inhibits peritoneal metastasis AE Ryan, A Colleran, A O'gorman, L O'flynn, J Pindjacova, P Lohan, ... Oncogene 34 (12), 1563-1574, 2015 | 61 | 2015 |