Generation of functional human pancreatic β cells in vitro FW Pagliuca, JR Millman, M Gürtler, M Segel, A Van Dervort, JH Ryu, ... Cell 159 (2), 428-439, 2014 | 2260 | 2014 |
Long-term glycemic control using polymer-encapsulated human stem cell–derived beta cells in immune-competent mice AJ Vegas, O Veiseh, M Gürtler, JR Millman, FW Pagliuca, AR Bader, ... Nature medicine 22 (3), 306-311, 2016 | 726 | 2016 |
Generation of stem cell-derived β-cells from patients with type 1 diabetes JR Millman, C Xie, A Van Dervort, M Gürtler, FW Pagliuca, DA Melton Nature communications 7 (1), 11463, 2016 | 437 | 2016 |
Differentiated human stem cells resemble fetal, not adult, β cells S Hrvatin, CW O’Donnell, F Deng, JR Millman, FW Pagliuca, P DiIorio, ... Proceedings of the National Academy of Sciences 111 (8), 3038-3043, 2014 | 363 | 2014 |
Acquisition of dynamic function in human stem cell-derived β cells L Velazco-Cruz, J Song, KG Maxwell, MM Goedegebuure, ... Stem cell reports 12 (2), 351-365, 2019 | 350 | 2019 |
Targeting the cytoskeleton to direct pancreatic differentiation of human pluripotent stem cells NJ Hogrebe, P Augsornworawat, KG Maxwell, L Velazco-Cruz, ... Nature biotechnology 38 (4), 460-470, 2020 | 285 | 2020 |
Anisotropic particle synthesis in dielectrophoretically controlled microdroplet reactors JR Millman, KH Bhatt, BG Prevo, OD Velev Nature materials 4 (1), 98-102, 2005 | 284 | 2005 |
Gene-edited human stem cell–derived β cells from a patient with monogenic diabetes reverse preexisting diabetes in mice KG Maxwell, P Augsornworawat, L Velazco-Cruz, MH Kim, R Asada, ... Science translational medicine 12 (540), eaax9106, 2020 | 157 | 2020 |
Single-cell transcriptome profiling reveals β cell maturation in stem cell-derived islets after transplantation P Augsornworawat, KG Maxwell, L Velazco-Cruz, JR Millman Cell reports 32 (8), 2020 | 155 | 2020 |
Generation of insulin-producing pancreatic β cells from multiple human stem cell lines NJ Hogrebe, KG Maxwell, P Augsornworawat, JR Millman Nature protocols 16 (9), 4109-4143, 2021 | 117 | 2021 |
Autologous pluripotent stem cell–derived β-like cells for diabetes cellular therapy JR Millman, FW Pagliuca Diabetes 66 (5), 1111-1120, 2017 | 102 | 2017 |
A nanofibrous encapsulation device for safe delivery of insulin-producing cells to treat type 1 diabetes X Wang, KG Maxwell, K Wang, DT Bowers, JA Flanders, W Liu, LH Wang, ... Science translational medicine 13 (596), eabb4601, 2021 | 101 | 2021 |
Applications of iPSC-derived beta cells from patients with diabetes KG Maxwell, JR Millman Cell Reports Medicine 2 (4), 2021 | 91 | 2021 |
The effects of low oxygen on self-renewal and differentiation of embryonic stem cells JR Millman, JH Tan, CK Colton Current opinion in organ transplantation 14 (6), 694-700, 2009 | 85 | 2009 |
Economic 3D-printing approach for transplantation of human stem cell-derived β-like cells J Song, JR Millman Biofabrication 9 (1), 015002, 2016 | 83 | 2016 |
Effects of oxygen on mouse embryonic stem cell growth, phenotype retention, and cellular energetics DE Powers, JR Millman, RB Huang, CK Colton Biotechnology and bioengineering 101 (2), 241-254, 2008 | 77 | 2008 |
SC-β cells and compositions and methods for generating the same QP Peterson, FJ Pagliuca, DA Melton, JR Millman, MS Segel, M Gurtler US Patent 10,030,229, 2018 | 68 | 2018 |
Developments in stem cell-derived islet replacement therapy for treating type 1 diabetes NJ Hogrebe, M Ishahak, JR Millman Cell Stem Cell 30 (5), 530-548, 2023 | 64 | 2023 |
Advances toward engineering functionally mature human pluripotent stem cell-derived β cells L Velazco-Cruz, MM Goedegebuure, JR Millman Frontiers in Bioengineering and Biotechnology 8, 557823, 2020 | 55 | 2020 |
Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques X Hu, K White, AG Olroyd, R DeJesus, AA Dominguez, WE Dowdle, ... Nature biotechnology 42 (3), 413-423, 2024 | 47 | 2024 |