Targeting of porous hybrid silica nanoparticles to cancer cells JM Rosenholm, A Meinander, E Peuhu, R Niemi, JE Eriksson, C Sahlgren, ... ACS nano 3 (1), 197-206, 2009 | 596 | 2009 |
Mesoporous silica nanoparticles as drug delivery systems for targeted inhibition of Notch signaling in cancer V Mamaeva, JM Rosenholm, LT Bate-Eya, L Bergman, E Peuhu, ... Molecular Therapy 19 (8), 1538-1546, 2011 | 264 | 2011 |
Targeted intracellular delivery of hydrophobic agents using mesoporous hybrid silica nanoparticles as carrier systems JM Rosenholm, E Peuhu, JE Eriksson, C Sahlgren, M Lindén Nano letters 9 (9), 3308-3311, 2009 | 260 | 2009 |
Cancer‐cell‐specific induction of apoptosis using mesoporous silica nanoparticles as drug‐delivery vectors JM Rosenholm, E Peuhu, LT Bate‐Eya, JE Eriksson, C Sahlgren, ... Small 6 (11), 1234-1241, 2010 | 215 | 2010 |
L-type calcium channels regulate filopodia stability and cancer cell invasion downstream of integrin signalling G Jacquemet, H Baghirov, M Georgiadou, H Sihto, E Peuhu, ... Nature communications 7 (1), 13297, 2016 | 173 | 2016 |
SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras J Lilja, T Zacharchenko, M Georgiadou, G Jacquemet, ND Franceschi, ... Nature cell biology 19 (4), 292-305, 2017 | 135 | 2017 |
Fetal liver endothelium regulates the seeding of tissue-resident macrophages P Rantakari, N Jäppinen, E Lokka, E Mokkala, H Gerke, E Peuhu, J Ivaska, ... Nature 538 (7625), 392-396, 2016 | 81 | 2016 |
SORLA regulates endosomal trafficking and oncogenic fitness of HER2 M Pietilä, P Sahgal, E Peuhu, NZ Jäntti, I Paatero, E Närvä, H Al-Akhrass, ... Nature Communications 10 (1), 2340, 2019 | 58 | 2019 |
PP2A inhibitor PME-1 drives kinase inhibitor resistance in glioma cells A Kaur, OV Denisova, X Qiao, M Jumppanen, E Peuhu, SU Ahmed, ... Cancer research 76 (23), 7001-7011, 2016 | 58 | 2016 |
Epithelial vimentin plays a functional role in mammary gland development E Peuhu, R Virtakoivu, A Mai, A Wärri, J Ivaska Development 144 (22), 4103-4113, 2017 | 57 | 2017 |
Inhibition of Akt signaling by the lignan matairesinol sensitizes prostate cancer cells to TRAIL-induced apoptosis E Peuhu, A Rivero-Müller, H Stykki, E Torvaldson, T Holmbom, P Eklund, ... Oncogene 29 (6), 898-908, 2010 | 56 | 2010 |
Integrin signaling and mechanotransduction in regulation of somatic stem cells A Isomursu, M Lerche, ME Taskinen, J Ivaska, E Peuhu Experimental cell research 378 (2), 217-225, 2019 | 50 | 2019 |
SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland E Peuhu, R Kaukonen, M Lerche, M Saari, C Guzmán, P Rantakari, ... The EMBO Journal 36 (2), 165-182, 2017 | 47 | 2017 |
The antitumor lignan Nortrachelogenin sensitizes prostate cancer cells to TRAIL-induced cell death by inhibition of the Akt pathway and growth factor signaling E Peuhu, P Paul, M Remes, T Holmbom, P Eklund, R Sjöholm, ... Biochemical pharmacology 86 (5), 571-583, 2013 | 38 | 2013 |
CIP2A interacts with TopBP1 and drives basal-like breast cancer tumorigenesis A Laine, SG Nagelli, C Farrington, U Butt, AN Cvrljevic, JP Vainonen, ... Cancer research 81 (16), 4319-4331, 2021 | 37 | 2021 |
Mutually exclusive roles of SHARPIN in integrin inactivation and NF-κB signaling N De Franceschi, E Peuhu, M Parsons, S Rissanen, I Vattulainen, ... PloS one 10 (11), e0143423, 2015 | 30 | 2015 |
Anti-inflammatory effects of nortrachelogenin in murine J774 macrophages and in carrageenan-induced paw edema model in the mouse M Laavola, T Leppänen, H Eräsalo, M Hämäläinen, R Nieminen, ... Planta Medica 234 (06), 519-526, 2017 | 27 | 2017 |
Integrin binding dynamics modulate ligand-specific mechanosensing in mammary gland fibroblasts M Lerche, A Elosegui-Artola, JZ Kechagia, C Guzmán, M Georgiadou, ... Iscience 23 (3), 2020 | 22 | 2020 |
Integrin-mediated adhesion and mechanosensing in the mammary gland O Paavolainen, E Peuhu Seminars in Cell & Developmental Biology 114, 113-125, 2021 | 19 | 2021 |
Integrin beta 1 inhibition alleviates the chronic hyperproliferative dermatitis phenotype of SHARPIN-deficient mice E Peuhu, SI Salomaa, N De Franceschi, CS Potter, JP Sundberg, ... PLoS One 12 (10), e0186628, 2017 | 18 | 2017 |