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Leandro Cerchietti
Leandro Cerchietti
Weill Cornell Medicine
在 med.cornell.edu 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation
W Béguelin, R Popovic, M Teater, Y Jiang, KL Bunting, M Rosen, H Shen, ...
Cancer cell 23 (5), 677-692, 2013
9172013
Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models
E Caldas-Lopes, L Cerchietti, JH Ahn, CC Clement, AI Robles, A Rodina, ...
Proceedings of the National Academy of Sciences 106 (20), 8368-8373, 2009
3712009
Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells
JM Polo, T Dell'Oso, SM Ranuncolo, L Cerchietti, D Beck, GF Da Silva, ...
Nature medicine 10 (12), 1329-1335, 2004
3532004
A small-molecule inhibitor of BCL6 kills DLBCL cells in vitro and in vivo
LC Cerchietti, AF Ghetu, X Zhu, GF Da Silva, S Zhong, M Matthews, ...
Cancer cell 17 (4), 400-411, 2010
3472010
Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90
K Moulick, JH Ahn, H Zong, A Rodina, L Cerchietti, EM Gomes DaGama, ...
Nature chemical biology 7 (11), 818-826, 2011
3012011
The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL
W Ci, JM Polo, L Cerchietti, R Shaknovich, L Wang, SN Yang, K Ye, ...
Blood, The Journal of the American Society of Hematology 113 (22), 5536-5548, 2009
2732009
MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivo
L Fontan, C Yang, V Kabaleeswaran, L Volpon, MJ Osborne, E Beltran, ...
Cancer cell 22 (6), 812-824, 2012
2712012
Midazolam as adjunct therapy to morphine in the alleviation of severe dyspnea perception in patients with advanced cancer
AH Navigante, LCA Cerchietti, MA Castro, MA Lutteral, ME Cabalar
Journal of pain and symptom management 31 (1), 38-47, 2006
2692006
The epichaperome is an integrated chaperome network that facilitates tumour survival
A Rodina, T Wang, P Yan, EDG Gomes, MPS Dunphy, N Pillarsetty, ...
Nature 538 (7625), 397-401, 2016
2582016
Kaiso-deficient mice show resistance to intestinal cancer
A Prokhortchouk, O Sansom, J Selfridge, IM Caballero, S Salozhin, ...
Molecular and cellular biology 26 (1), 199-208, 2006
2322006
BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR–ABL1 kinase inhibition
C Duy, C Hurtz, S Shojaee, L Cerchietti, H Geng, S Swaminathan, ...
Nature 473 (7347), 384-388, 2011
2162011
Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma
T Clozel, SN Yang, RL Elstrom, W Tam, P Martin, M Kormaksson, ...
Cancer discovery 3 (9), 1002-1019, 2013
2142013
A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6–dependent B cell lymphomas
LC Cerchietti, EC Lopes, SN Yang, K Hatzi, KL Bunting, LA Tsikitas, ...
Nature medicine 15 (12), 1369-1376, 2009
2062009
Effect of topical morphine for mucositis‐associated pain following concomitant chemoradiotherapy for head and neck carcinoma
LCA Cerchietti, AH Navigante, MR Bonomi, MA Zaderajko, PR Menéndez, ...
Cancer: Interdisciplinary International Journal of the American Cancer …, 2002
2042002
The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation
HA Zahreddine, B Culjkovic-Kraljacic, S Assouline, P Gendron, ...
Nature 511 (7507), 90-93, 2014
2002014
A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo
LC Cerchietti, SN Yang, R Shaknovich, K Hatzi, JM Polo, A Chadburn, ...
Blood, The Journal of the American Society of Hematology 113 (15), 3397-3405, 2009
1962009
BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia
C Hurtz, K Hatzi, L Cerchietti, M Braig, E Park, Y Kim, S Herzog, ...
Journal of Experimental Medicine 208 (11), 2163-2174, 2011
1932011
A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters
K Hatzi, Y Jiang, C Huang, F Garrett-Bakelman, MD Gearhart, ...
Cell reports 4 (3), 578-588, 2013
1912013
Limits in the detection of m6A changes using MeRIP/m6A-seq
ABR McIntyre, NS Gokhale, L Cerchietti, SR Jaffrey, SM Horner, ...
Scientific reports 10 (1), 6590, 2020
1762020
DNA methylation signatures define molecular subtypes of diffuse large B-cell lymphoma
R Shaknovich, H Geng, NA Johnson, L Tsikitas, L Cerchietti, JM Greally, ...
Blood, The Journal of the American Society of Hematology 116 (20), e81-e89, 2010
1742010
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