| Simultaneous identification of bacterial virulence genes by negative selection M Hensel, JE Shea, C Gleeson, MD Jones, E Dalton, DW Holden Science 269 (5222), 400-403, 1995 | 1593 | 1995 |
| Identification of a virulence locus encoding a second type III secretion system in Salmonella typhimurium. JE Shea, M Hensel, C Gleeson, DW Holden Proceedings of the National Academy of Sciences 93 (6), 2593-2597, 1996 | 1042 | 1996 |
| Genes encoding putative effector proteins of the type III secretion system of Salmonella pathogenicity island 2 are required for bacterial virulence and proliferation … M Hensel, JE Shea, SR Waterman, R Mundy, T Nikolaus, G Banks, ... Molecular microbiology 30 (1), 163-174, 1998 | 780 | 1998 |
| Internalization of Salmonella by macrophages induces formation of nonreplicating persisters S Helaine, AM Cheverton, KG Watson, LM Faure, SA Matthews, ... Science 343 (6167), 204-208, 2014 | 770 | 2014 |
| Salmonella pathogenicity island 2-dependent evasion of the phagocyte NADPH oxidase A Vazquez-Torres, Y Xu, J Jones-Carson, DW Holden, SM Lucia, ... Science 287 (5458), 1655-1658, 2000 | 726 | 2000 |
| Salmonella maintains the integrity of its intracellular vacuole through the action of SifA CR Beuzón, S Méresse, KE Unsworth, J Ruíz-Albert, S Garvis, ... The EMBO journal 19 (13), 3235-3249, 2000 | 715 | 2000 |
| A pneumococcal pilus influences virulence and host inflammatory responses MA Barocchi, J Ries, X Zogaj, C Hemsley, B Albiger, A Kanth, S Dahlberg, ... Proceedings of the National Academy of Sciences 103 (8), 2857-2862, 2006 | 615 | 2006 |
| Identification of Staphylococcus aureus virulence genes in a murine model of bacteraemia using signature‐tagged mutagenesis JM Mei, F Nourbakhsh, CW Ford, DW Holden Molecular microbiology 26 (2), 399-407, 1997 | 554 | 1997 |
| Functions and effectors of the Salmonella pathogenicity island 2 type III secretion system SR Waterman, DW Holden Cellular microbiology 5 (8), 501-511, 2003 | 520 | 2003 |
| The classical pathway is the dominant complement pathway required for innate immunity to Streptococcus pneumoniae infection in mice JS Brown, T Hussell, SM Gilliland, DW Holden, JC Paton, MR Ehrenstein, ... Proceedings of the National Academy of Sciences 99 (26), 16969-16974, 2002 | 502 | 2002 |
| Functions of the Salmonella pathogenicity island 2 (SPI-2) type III secretion system effectors R Figueira, DW Holden Microbiology 158 (5), 1147-1161, 2012 | 444 | 2012 |
| Salmonella SPI-2 type III secretion system effectors: molecular mechanisms and physiological consequences E Jennings, TLM Thurston, DW Holden Cell host & microbe 22 (2), 217-231, 2017 | 363 | 2017 |
| A Streptococcus pneumoniae pathogenicity island encoding an ABC transporter involved in iron uptake and virulence JS Brown, SM Gilliland, DW Holden Molecular microbiology 40 (3), 572-585, 2001 | 356 | 2001 |
| Dynamics of intracellular bacterial replication at the single cell level S Helaine, JA Thompson, KG Watson, M Liu, C Boyle, DW Holden Proceedings of the National Academy of Sciences 107 (8), 3746-3751, 2010 | 354 | 2010 |
| A functional genomic analysis of type 3 Streptococcus pneumoniae virulence GW Lau, S Haataja, M Lonetto, SE Kensit, A Marra, AP Bryant, D McDevitt, ... Molecular microbiology 40 (3), 555-571, 2001 | 339 | 2001 |
| Gene transfer system for the phytopathogenic fungus Ustilago maydis. JUN Wang, DW Holden, SA Leong Proceedings of the National Academy of Sciences 85 (3), 865-869, 1988 | 329 | 1988 |
| Complementary activities of SseJ and SifA regulate dynamics of the Salmonella typhimurium vacuolar membrane J Ruiz‐Albert, XJ Yu, CR Beuzón, AN Blakey, EE Galyov, DW Holden Molecular microbiology 44 (3), 645-661, 2002 | 319 | 2002 |
| Intracellular replication of Salmonella typhimurium strains in specific subsets of splenic macrophages in vivo SP Salcedo, M Noursadeghi, J Cohen, DW Holden Cellular microbiology 3 (9), 587-597, 2001 | 311 | 2001 |
| SseL, a Salmonella deubiquitinase required for macrophage killing and virulence A Rytkönen, J Poh, J Garmendia, C Boyle, A Thompson, M Liu, ... Proceedings of the National Academy of Sciences 104 (9), 3502-3507, 2007 | 283 | 2007 |
| In vivo genetic analysis of bacterial virulence SL Chiang, JJ Mekalanos, DW Holden Annual Reviews in Microbiology 53 (1), 129-154, 1999 | 278 | 1999 |
