STAT3-mediated up-regulation of BLIMP1 Is coordinated with BCL6 down-regulation to control human plasma cell differentiation SA Diehl, H Schmidlin, M Nagasawa, SD van Haren, MJ Kwakkenbos, ... The Journal of Immunology 180 (7), 4805-4815, 2008 | 308 | 2008 |
Dynamic molecular changes during the first week of human life follow a robust developmental trajectory AH Lee, CP Shannon, N Amenyogbe, TB Bennike, J Diray-Arce, OT Idoko, ... Nature communications 10 (1), 1092, 2019 | 159 | 2019 |
Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses DJ Dowling, EA Scott, A Scheid, I Bergelson, S Joshi, C Pietrasanta, ... Journal of Allergy and Clinical Immunology 140 (5), 1339-1350, 2017 | 156 | 2017 |
Age-specific adjuvant synergy: dual TLR7/8 and mincle activation of human newborn dendritic cells enables Th1 polarization SD Van Haren, DJ Dowling, W Foppen, D Christensen, P Andersen, ... The Journal of Immunology 197 (11), 4413-4424, 2016 | 98 | 2016 |
TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth DJ Dowling, SD van Haren, A Scheid, I Bergelson, D Kim, CJ Mancuso, ... JCI insight 2 (6), 2017 | 97 | 2017 |
Soluble mediators regulating immunity in early life MA Pettengill, SD van Haren, O Levy Frontiers in immunology 5, 110462, 2014 | 94 | 2014 |
HLA-DR-presented peptide repertoires derived from human monocyte-derived dendritic cells pulsed with blood coagulation factor VIII SD van Haren, E Herczenik, A ten Brinke, K Mertens, J Voorberg, ... Molecular & Cellular Proteomics 10 (6), 2011 | 88 | 2011 |
Licensed Bacille Calmette-Guérin (BCG) formulations differ markedly in bacterial viability, RNA content and innate immune activation A Angelidou, MG Conti, J Diray-Arce, CS Benn, F Shann, MG Netea, ... Vaccine 38 (9), 2229-2240, 2020 | 87 | 2020 |
Uptake of blood coagulation factor VIII by dendritic cells is mediated via its C1 domain E Herczenik, SD van Haren, A Wroblewska, P Kaijen, ... Journal of Allergy and Clinical Immunology 129 (2), 501-509. e5, 2012 | 87 | 2012 |
Uptake of blood coagulation factor VIII by dendritic cells is mediated via its C1 domain E Herczenik, SD van Haren, A Wroblewska, P Kaijen, ... Journal of allergy and clinical immunology 129 (2), 501-509. e5, 2012 | 87 | 2012 |
An aluminum hydroxide: CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice E Nanishi, F Borriello, TR O’Meara, ME McGrath, Y Saito, RE Haupt, ... Science Translational Medicine 14 (629), eabj5305, 2021 | 74 | 2021 |
BCG as a case study for precision vaccine development: lessons from vaccine heterogeneity, trained immunity, and immune ontogeny A Angelidou, J Diray-Arce, MG Conti, KK Smolen, SD van Haren, ... Frontiers in Microbiology 11, 481431, 2020 | 71 | 2020 |
The imidazoquinoline toll-like receptor-7/8 agonist hybrid-2 potently induces cytokine production by human newborn and adult leukocytes L Ganapathi, S Van Haren, DJ Dowling, I Bergelson, NM Shukla, ... PLoS One 10 (8), e0134640, 2015 | 60 | 2015 |
Preferential HLA-DRB1* 11–dependent presentation of CUB2-derived peptides by ADAMTS13-pulsed dendritic cells N Sorvillo, SD van Haren, PH Kaijen, A ten Brinke, R Fijnheer, AB Meijer, ... Blood, The Journal of the American Society of Hematology 121 (17), 3502-3510, 2013 | 59 | 2013 |
In vitro cytokine induction by TLR-activating vaccine adjuvants in human blood varies by age and adjuvant SD Van Haren, L Ganapathi, I Bergelson, DJ Dowling, M Banks, ... Cytokine 83, 99-109, 2016 | 53 | 2016 |
T‐cell responses in two unrelated hemophilia A inhibitor subjects include an epitope at the factor VIII R593C missense site EA James, SD Van Haren, RA Ettinger, K Fijnvandraat, JA Liberman, ... Journal of Thrombosis and Haemostasis 9 (4), 689-699, 2011 | 50 | 2011 |
Modification of an exposed loop in the C1 domain reduces immune responses to factor VIII in hemophilia A mice A Wroblewska, SD van Haren, E Herczenik, P Kaijen, A Ruminska, SY Jin, ... Blood, The Journal of the American Society of Hematology 119 (22), 5294-5300, 2012 | 45 | 2012 |
Distinct TLR-mediated cytokine production and immunoglobulin secretion in human newborn naive B cells MA Pettengill, SD van Haren, N Li, DJ Dowling, I Bergelson, J Jans, ... Innate immunity 22 (6), 433-443, 2016 | 42 | 2016 |
Factor VIII‐specific B cell responses in haemophilia A patients with inhibitors PMW Van Helden, SD Van Haren, K Fijnvandraat, ... Haemophilia 16 (102), 35-43, 2010 | 39 | 2010 |
Limited promiscuity of HLA-DRB1 presented peptides derived of blood coagulation factor VIII SD van Haren, A Wroblewska, E Herczenik, PH Kaijen, A Ruminska, ... PLoS One 8 (11), e80239, 2013 | 31 | 2013 |