关注
Simon D. van Haren
Simon D. van Haren
Boston Children's Hospital
在 childrens.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
STAT3-mediated up-regulation of BLIMP1 Is coordinated with BCL6 down-regulation to control human plasma cell differentiation
SA Diehl, H Schmidlin, M Nagasawa, SD van Haren, MJ Kwakkenbos, ...
The Journal of Immunology 180 (7), 4805-4815, 2008
3082008
Dynamic molecular changes during the first week of human life follow a robust developmental trajectory
AH Lee, CP Shannon, N Amenyogbe, TB Bennike, J Diray-Arce, OT Idoko, ...
Nature communications 10 (1), 1092, 2019
1592019
Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses
DJ Dowling, EA Scott, A Scheid, I Bergelson, S Joshi, C Pietrasanta, ...
Journal of Allergy and Clinical Immunology 140 (5), 1339-1350, 2017
1562017
Age-specific adjuvant synergy: dual TLR7/8 and mincle activation of human newborn dendritic cells enables Th1 polarization
SD Van Haren, DJ Dowling, W Foppen, D Christensen, P Andersen, ...
The Journal of Immunology 197 (11), 4413-4424, 2016
982016
TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth
DJ Dowling, SD van Haren, A Scheid, I Bergelson, D Kim, CJ Mancuso, ...
JCI insight 2 (6), 2017
972017
Soluble mediators regulating immunity in early life
MA Pettengill, SD van Haren, O Levy
Frontiers in immunology 5, 110462, 2014
942014
HLA-DR-presented peptide repertoires derived from human monocyte-derived dendritic cells pulsed with blood coagulation factor VIII
SD van Haren, E Herczenik, A ten Brinke, K Mertens, J Voorberg, ...
Molecular & Cellular Proteomics 10 (6), 2011
882011
Licensed Bacille Calmette-Guérin (BCG) formulations differ markedly in bacterial viability, RNA content and innate immune activation
A Angelidou, MG Conti, J Diray-Arce, CS Benn, F Shann, MG Netea, ...
Vaccine 38 (9), 2229-2240, 2020
872020
Uptake of blood coagulation factor VIII by dendritic cells is mediated via its C1 domain
E Herczenik, SD van Haren, A Wroblewska, P Kaijen, ...
Journal of Allergy and Clinical Immunology 129 (2), 501-509. e5, 2012
872012
Uptake of blood coagulation factor VIII by dendritic cells is mediated via its C1 domain
E Herczenik, SD van Haren, A Wroblewska, P Kaijen, ...
Journal of allergy and clinical immunology 129 (2), 501-509. e5, 2012
872012
An aluminum hydroxide: CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice
E Nanishi, F Borriello, TR O’Meara, ME McGrath, Y Saito, RE Haupt, ...
Science Translational Medicine 14 (629), eabj5305, 2021
742021
BCG as a case study for precision vaccine development: lessons from vaccine heterogeneity, trained immunity, and immune ontogeny
A Angelidou, J Diray-Arce, MG Conti, KK Smolen, SD van Haren, ...
Frontiers in Microbiology 11, 481431, 2020
712020
The imidazoquinoline toll-like receptor-7/8 agonist hybrid-2 potently induces cytokine production by human newborn and adult leukocytes
L Ganapathi, S Van Haren, DJ Dowling, I Bergelson, NM Shukla, ...
PLoS One 10 (8), e0134640, 2015
602015
Preferential HLA-DRB1* 11–dependent presentation of CUB2-derived peptides by ADAMTS13-pulsed dendritic cells
N Sorvillo, SD van Haren, PH Kaijen, A ten Brinke, R Fijnheer, AB Meijer, ...
Blood, The Journal of the American Society of Hematology 121 (17), 3502-3510, 2013
592013
In vitro cytokine induction by TLR-activating vaccine adjuvants in human blood varies by age and adjuvant
SD Van Haren, L Ganapathi, I Bergelson, DJ Dowling, M Banks, ...
Cytokine 83, 99-109, 2016
532016
T‐cell responses in two unrelated hemophilia A inhibitor subjects include an epitope at the factor VIII R593C missense site
EA James, SD Van Haren, RA Ettinger, K Fijnvandraat, JA Liberman, ...
Journal of Thrombosis and Haemostasis 9 (4), 689-699, 2011
502011
Modification of an exposed loop in the C1 domain reduces immune responses to factor VIII in hemophilia A mice
A Wroblewska, SD van Haren, E Herczenik, P Kaijen, A Ruminska, SY Jin, ...
Blood, The Journal of the American Society of Hematology 119 (22), 5294-5300, 2012
452012
Distinct TLR-mediated cytokine production and immunoglobulin secretion in human newborn naive B cells
MA Pettengill, SD van Haren, N Li, DJ Dowling, I Bergelson, J Jans, ...
Innate immunity 22 (6), 433-443, 2016
422016
Factor VIII‐specific B cell responses in haemophilia A patients with inhibitors
PMW Van Helden, SD Van Haren, K Fijnvandraat, ...
Haemophilia 16 (102), 35-43, 2010
392010
Limited promiscuity of HLA-DRB1 presented peptides derived of blood coagulation factor VIII
SD van Haren, A Wroblewska, E Herczenik, PH Kaijen, A Ruminska, ...
PLoS One 8 (11), e80239, 2013
312013
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