Early life stress is a risk factor for excessive alcohol drinking and impulsivity in adults and is mediated via a CRF/GABAA mechanism MC Gondré-Lewis, KT Warnock, H Wang, HL June Jr, KA Bell, H Rabe, ... Stress 19 (2), 235-247, 2016 | 99 | 2016 |
Synthesis of Bisindole Alkaloids from the Apocynaceae Which Contain a Macroline or Sarpagine Unit: A Review VVNPBTJMC Md Toufiqur Rahman molecules 21 (11), 1525, 2016 | 48 | 2016 |
Bioisosteres of ethyl 8-ethynyl-6-(pyridin-2-yl)-4H-benzo [f] imidazo [1, 5-a][1, 4] diazepine-3-carboxylate (HZ-166) as novel alpha 2, 3 selective potentiators of GABAA … JM Witkin, JL Smith, X Ping, SD Gleason, MM Poe, G Li, X Jin, J Hobbs, ... Neuropharmacology 137, 332-343, 2018 | 36 | 2018 |
Concise Total Synthesis of (−)‐Affinisine Oxindole,(+)‐Isoalstonisine,(+)‐Alstofoline,(−)‐Macrogentine,(+)‐Na‐Demethylalstonisine,(−)‐Alstonoxine A, and (+)‐Alstonisine MR Stephen, MT Rahman, VVNPB Tiruveedhula, GO Fonseca, ... Chemistry-A European Journal 23 (62), 15805-15819, 2017 | 27 | 2017 |
Evidence that sedative effects of benzodiazepines involve unexpected GABAA receptor subtypes: quantitative observation studies in rhesus monkeys AN Duke, Z Meng, DM Platt, JR Atack, GR Dawson, DS Reynolds, ... Journal of Pharmacology and Experimental Therapeutics 366 (1), 145-157, 2018 | 24 | 2018 |
Triple monoamine uptake inhibitors demonstrate a pharmacologic association between excessive drinking and impulsivity in high‐alcohol‐preferring (HAP) mice DS O'Tousa, KT Warnock, LM Matson, OA Namjoshi, MV Linn, ... Addiction biology 20 (2), 236-247, 2015 | 19 | 2015 |
An antidepressant-related pharmacological signature for positive allosteric modulators of α2/3-containing GABAA receptors KR Methuku, X Li, R Cerne, SD Gleason, JM Schkeryantz, V Tiruveedhula, ... Pharmacology Biochemistry and Behavior 170, 9-13, 2018 | 17 | 2018 |
Little Evidence of a Role for the α1GABAA Subunit‐Containing Receptor in a Rhesus Monkey Model of Alcohol Drinking EK Sawyer, C Moran, MH Sirbu, M Szafir, M Van Linn, O Namjoshi, ... Alcoholism: Clinical and Experimental Research 38 (4), 1108-1117, 2014 | 17 | 2014 |
Base-mediated stereospecific synthesis of aryloxy and amino substituted ethyl acrylates MS Kabir, OA Namjoshi, R Verma, M Lorenz, ... The Journal of Organic Chemistry 77 (1), 300-310, 2012 | 17 | 2012 |
Duration of treatment and activation of α1-containing GABAA receptors variably affect the level of anxiety and seizure susceptibility after diazepam withdrawal in rats J Kovačević, T Timić, VV Tiruveedhula, B Batinić, OA Namjoshi, M Milić, ... Brain research bulletin 104, 1-6, 2014 | 16 | 2014 |
Neurobiological correlates of state-dependent context fear MAA Meyer, KA Corcoran, HJ Chen, S Gallego, G Li, VV Tiruveedhula, ... Learning & Memory 24, 385-391, 2017 | 15 | 2017 |
Synthesis of aza and carbocyclic β-carbolines for the treatment of alcohol abuse. Regiospecific solution to the problem of 3, 6-disubstituted β-and aza-β-carboline specificity VVNPB Tiruveedhula, KR Methuku, JR Deschamps, JM Cook Organic & biomolecular chemistry 13 (43), 10705-10715, 2015 | 15 | 2015 |
Design and synthesis of novel antimicrobials with activity against Gram-positive bacteria and mycobacterial species, including M. tuberculosis VVNPB Tiruveedhula, CM Witzigmann, R Verma, MS Kabir, M Rott, ... Bioorganic & medicinal chemistry 21 (24), 7830-7840, 2013 | 15 | 2013 |
βCCT, an antagonist selective for α1GABAA receptors, reverses diazepam withdrawal-induced anxiety in rats J Divljaković, M Milić, OA Namjoshi, VV Tiruveedhula, T Timić, JM Cook, ... Brain research bulletin 91, 1-7, 2013 | 15 | 2013 |
Synthesis of chiral GABAA receptor subtype selective ligands as potential agents to treat schizophrenia as well as depression G Li, MR Stephen, R Kodali, NM Zahn, MM Poe, VVNPB Tiruveedhula, ... ARKIVOC: free online journal of organic chemistry 2018 (4), 158, 2018 | 14 | 2018 |
Imidazodiazepine anticonvulsant, KRM-II-81, produces novel, non-diazepam-like antiseizure effects DE Knutson, JL Smith, X Ping, X Jin, LK Golani, G Li, ... ACS Chemical Neuroscience 11 (17), 2624-2637, 2020 | 11 | 2020 |
Effects of the benzodiazepine GABAA α1-preferring antagonist 3-isopropoxy-β-carboline hydrochloride (3-ISOPBC) on alcohol seeking and self-administration in baboons AF Holtyn, VVNPB Tiruveedhula, MR Stephen, JM Cook, EM Weerts Drug and alcohol dependence 170, 25-31, 2017 | 11 | 2017 |
Stereospecific total synthesis of the indole alkaloid ervincidine. Establishment of the C-6 hydroxyl stereochemistry SK Rallapalli, OA Namjoshi, VVNPB Tiruveedhula, JR Deschamps, ... The Journal of organic chemistry 79 (9), 3776-3780, 2014 | 11 | 2014 |
Tolerance and dependence following chronic alprazolam treatment in rhesus monkeys: Role of GABAA receptor subtypes AN Duke, VVNPB Tiruveedhula, D Sharmin, DE Knutson, JM Cook, ... Drug and alcohol dependence 228, 108985, 2021 | 9 | 2021 |
Non-sedating benzodiazepines cause paralysis and tissue damage in the parasitic blood fluke Schistosoma mansoni P McCusker, MY Mian, G Li, MD Olp, VVNPB Tiruveedhula, F Rashid, ... PLoS Neglected Tropical Diseases 13 (11), e0007826, 2019 | 9 | 2019 |