| Selective entrapment of extrachromosomally amplified DNA by nuclear budding and micronucleation during S phase N Shimizu, N Itoh, H Utiyama, GM Wahl The Journal of cell biology 140 (6), 1307, 1998 | 453 | 1998 |
| A hyper‐dynamic equilibrium between promoter‐bound and nucleoplasmic dimers controls NF‐κB‐dependent gene activity D Bosisio, I Marazzi, A Agresti, N Shimizu, ME Bianchi, G Natoli The EMBO journal 25 (4), 798-810, 2006 | 254 | 2006 |
| Selective elimination of acentric double minutes from cancer cells through the extrusion of micronuclei N Shimizu, T Shimura, T Tanaka Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 448 (1 …, 2000 | 225 | 2000 |
| Emergence of micronuclei and their effects on the fate of cells under replication stress K Utani, Y Kohno, A Okamoto, N Shimizu PloS one 5 (4), e10089, 2010 | 198 | 2010 |
| When, where and how the bridge breaks: anaphase bridge breakage plays a crucial role in gene amplification and HSR generation N Shimizu, K Shingaki, Y Kaneko-Sasaguri, T Hashizume, T Kanda Experimental cell research 302 (2), 233-243, 2005 | 189 | 2005 |
| Tracking of microinjected DNA in live cells reveals the intracellular behavior and elimination of extrachromosomal genetic material N Shimizu, F Kamezaki, S Shigematsu Nucleic acids research 33 (19), 6296-6307, 2005 | 93 | 2005 |
| 2 ‘, 5 ‘-Oligoadenylate synthetase activity in lymphocytes from normal mouse. N Shimizu, Y Sokawa Journal of Biological Chemistry 254 (23), 12034-12037, 1979 | 92 | 1979 |
| Molecular mechanisms of the origin of micronuclei from extrachromosomal elements N Shimizu Mutagenesis 26 (1), 119-123, 2011 | 90 | 2011 |
| Selective capture of acentric fragments by micronuclei provides a rapid method for purifying extrachromosomally amplified DNA N Shimizu, T Kanda, GM Wahl Nature genetics 12 (1), 65-71, 1996 | 82 | 1996 |
| Plasmids with a mammalian replication origin and a matrix attachment region initiate the event similar to gene amplification N Shimizu, Y Miura, Y Sakamoto, K Tsutsui Cancer research 61 (19), 6987-6990, 2001 | 77 | 2001 |
| Induced detachment of acentric chromatin from mitotic chromosomes leads to their cytoplasmic localization at G1and the micronucleation by lamin reorganization at … T Tanaka, N Shimizu Journal of Cell Science 113 (4), 697-707, 2000 | 77 | 2000 |
| Nonselective DNA damage induced by a replication inhibitor results in the selective elimination of extrachromosomal double minutes from human cancer cells N Shimizu, N Misaka, K Utani Genes, Chromosomes and Cancer 46 (10), 865-874, 2007 | 75 | 2007 |
| Generation of micronuclei during interphase by coupling between cytoplasmic membrane blebbing and nuclear budding K Utani, A Okamoto, N Shimizu PloS one 6 (11), e27233, 2011 | 74 | 2011 |
| Extrachromosomal double minutes and chromosomal homogeneously staining regions as probes for chromosome research N Shimizu Cytogenetic and genome research 124 (3-4), 312-326, 2009 | 74 | 2009 |
| Loss of Amplified c-myc Genes in the Spontaneously Differentiated HL-60 Cells N Shimizu, H Nakamura, T Kadota, K Kitajima, T Oda, T Hirano, ... Cancer research 54 (13), 3561-3567, 1994 | 73 | 1994 |
| Amplification of plasmids containing a mammalian replication initiation region is mediated by controllable conflict between replication and transcription N Shimizu, T Hashizume, K Shingaki, J Kawamoto Cancer research 63 (17), 5281-5290, 2003 | 68 | 2003 |
| Expression of a novel immediate early gene during 12-O-tetradecanoylphorbol-13-acetate-induced macrophagic differentiation of HL-60 cells N Shimizu, M Ohta, C Fujiwara, J Sagara, N Mochizuki, T Oda, H Utiyama Journal of Biological Chemistry 266 (19), 12157-12161, 1991 | 68 | 1991 |
| DNA replication-dependent intranuclear relocation of double minute chromatin N Itoh, N Shimizu Journal of cell science 111 (22), 3275-3285, 1998 | 58 | 1998 |
| Micronuclei bearing acentric extrachromosomal chromatin are transcriptionally competent and may perturb the cancer cell phenotype K Utani, J Kawamoto, N Shimizu Molecular cancer research 5 (7), 695-704, 2007 | 56 | 2007 |
| Efficient recombinant production in mammalian cells using a novel IR/MAR gene amplification method Y Araki, T Hamafuji, C Noguchi, N Shimizu PLoS One 7 (7), e41787, 2012 | 55 | 2012 |
