Recon 2.2: from reconstruction to model of human metabolism N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ... Metabolomics 12, 1-7, 2016 | 321 | 2016 |
A consensus genome-scale reconstruction of Chinese hamster ovary cell metabolism H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ... Cell systems 3 (5), 434-443. e8, 2016 | 250 | 2016 |
Elementary flux modes in a nutshell: properties, calculation and applications J Zanghellini, DE Ruckerbauer, M Hanscho, C Jungreuthmayer Biotechnology journal 8 (9), 1009-1016, 2013 | 153 | 2013 |
Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time J Feichtinger, I Hernández, C Fischer, M Hanscho, N Auer, M Hackl, ... Biotechnology and bioengineering 113 (10), 2241-2253, 2016 | 145 | 2016 |
Nutritional requirements of the BY series of Saccharomyces cerevisiae strains for optimum growth M Hanscho, DE Ruckerbauer, N Chauhan, HF Hofbauer, S Krahulec, ... FEMS yeast research 12 (7), 796-808, 2012 | 125 | 2012 |
Reducing Recon 2 for steady-state flux analysis of HEK cell culture LE Quek, S Dietmair, M Hanscho, VS Martínez, N Borth, LK Nielsen Journal of biotechnology 184, 172-178, 2014 | 73 | 2014 |
What can mathematical modelling say about CHO metabolism and protein glycosylation? SN Galleguillos, D Ruckerbauer, MP Gerstl, N Borth, M Hanscho, ... Computational and structural biotechnology journal 15, 212-221, 2017 | 60 | 2017 |
What CHO is made of: Variations in the biomass composition of Chinese hamster ovary cell lines D Széliová, DE Ruckerbauer, SN Galleguillos, LB Petersen, K Natter, ... Metabolic engineering 61, 288-300, 2020 | 58 | 2020 |
Epigenetic regulation of gene expression in Chinese Hamster Ovary cells in response to the changing environment of a batch culture I Hernandez, H Dhiman, G Klanert, V Jadhav, N Auer, M Hanscho, ... Biotechnology and Bioengineering 116 (3), 677-692, 2019 | 44 | 2019 |
Avoiding the enumeration of infeasible elementary flux modes by including transcriptional regulatory rules in the enumeration process saves computational costs C Jungreuthmayer, DE Ruckerbauer, MP Gerstl, M Hanscho, ... PloS one 10 (6), e0129840, 2015 | 17 | 2015 |
Genetic and epigenetic variation across genes involved in energy metabolism and mitochondria of Chinese hamster ovary cell lines H Dhiman, MP Gerstl, D Ruckerbauer, M Hanscho, H Himmelbauer, ... Biotechnology Journal 14 (7), 1800681, 2019 | 16 | 2019 |
Inclusion of maintenance energy improves the intracellular flux predictions of CHO D Széliová, J Štor, I Thiel, M Weinguny, M Hanscho, G Lhota, N Borth, ... PLoS Computational Biology 17 (6), e1009022, 2021 | 8 | 2021 |
Designing minimal microbial strains of desired functionality using a genetic algorithm G Nair, C Jungreuthmayer, M Hanscho, J Zanghellini Algorithms for Molecular Biology 10, 1-13, 2015 | 7 | 2015 |
CHOmine: an integrated data warehouse for CHO systems biology and modeling MP Gerstl, M Hanscho, DE Ruckerbauer, J Zanghellini, N Borth Database 2017, bax034, 2017 | 6 | 2017 |
Toward Genome‐Scale Metabolic Pathway Analysis J Zanghellini, MP Gerstl, M Hanscho, G Nair, G Regensburger, S Müller, ... Industrial Biotechnology: Microorganisms 1, 111-123, 2017 | 5 | 2017 |
On-line clean-up and LC-MS analysis of primary metabolites in cell culture supernatants T Mairinger, J Tröndle, M Hanscho, S Hann Analytical Methods 9 (38), 5703-5710, 2017 | 3 | 2017 |
Transient manipulation of the expression level of selected growth rate correlating microRNAs does not increase growth rate in CHO-K1 cells G Klanert, N Bydlinski, P Agu, AB Diendorfer, M Hackl, M Hanscho, ... Journal of biotechnology 295, 63-70, 2019 | 2 | 2019 |
Designing optimized production hosts by metabolic modeling C Jungreuthmayer, MP Gerstl, DA Peña Navarro, M Hanscho, ... Metabolic Network Reconstruction and Modeling: Methods and Protocols, 371-387, 2018 | 1 | 2018 |
Determination of CHO biomass composition D Széliová, D Ruckerbauer, SN Galleguillos, M Hanscho, N Borth New Biotechnology 44, S144-S145, 2018 | | 2018 |
Investigating the metabolic limitations of Chinese hamster ovary (CHO) cells for recombinant protein production under fixed nutritional conditions S Galleguillos, M Hanscho, N Borth, J Zanghellini advances in Systems and Synthetic Biology, 2016 | | 2016 |