| Comprehensive genomic characterization defines human glioblastoma genes and core pathways Cancer Genome Atlas Research Network Tissue source sites: Duke University ... Nature 455 (7216), 1061-1068, 2008 | 7428 | 2008 |
| VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing DC Koboldt, Q Zhang, DE Larson, D Shen, MD McLellan, L Lin, CA Miller, ... Genome research 22 (3), 568-576, 2012 | 4879 | 2012 |
| Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia Cancer Genome Atlas Research Network New England Journal of Medicine 368 (22), 2059-2074, 2013 | 4722 | 2013 |
| Somatic mutations affect key pathways in lung adenocarcinoma L Ding, G Getz, DA Wheeler, ER Mardis, MD McLellan, K Cibulskis, ... Nature 455 (7216), 1069-1075, 2008 | 3108 | 2008 |
| Recurring mutations found by sequencing an acute myeloid leukemia genome ER Mardis, L Ding, DJ Dooling, DE Larson, MD McLellan, K Chen, ... New England Journal of Medicine 361 (11), 1058-1066, 2009 | 2689 | 2009 |
| Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing L Ding, TJ Ley, DE Larson, CA Miller, DC Koboldt, JS Welch, JK Ritchey, ... Nature 481 (7382), 506-510, 2012 | 2531 | 2012 |
| DNMT3A mutations in acute myeloid leukemia TJ Ley, L Ding, MJ Walter, MD McLellan, T Lamprecht, DE Larson, ... New England Journal of Medicine 363 (25), 2424-2433, 2010 | 2396 | 2010 |
| The Origin and Evolution of Mutations in Acute Myeloid Leukemia JS Welch, TJ Ley, DC Link, CA Miller, DE Larson, DC Koboldt, ... Cell 150 (2), 264-278, 2012 | 1834 | 2012 |
| BreakDancer: an algorithm for high-resolution mapping of genomic structural variation K Chen, JW Wallis, MD McLellan, DE Larson, JM Kalicki, CS Pohl, ... Nature Methods 6 (9), 677-681, 2009 | 1637 | 2009 |
| DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome TJ Ley, ER Mardis, L Ding, B Fulton, MD McLellan, K Chen, D Dooling, ... Nature 456 (7218), 66-72, 2008 | 1590 | 2008 |
| VarScan: variant detection in massively parallel sequencing of individual and pooled samples DC Koboldt, K Chen, T Wylie, DE Larson, MD McLellan, ER Mardis, ... Bioinformatics 25 (17), 2283-2285, 2009 | 1499 | 2009 |
| Genome remodelling in a basal-like breast cancer metastasis and xenograft L Ding, MJ Ellis, S Li, DE Larson, K Chen, JW Wallis, CC Harris, ... Nature 464 (7291), 999-1005, 2010 | 1351 | 2010 |
| The next-generation sequencing revolution and its impact on genomics DC Koboldt, KM Steinberg, DE Larson, RK Wilson, ER Mardis Cell 155 (1), 27-38, 2013 | 1292 | 2013 |
| Clonal architecture of secondary acute myeloid leukemia MJ Walter, D Shen, L Ding, J Shao, DC Koboldt, K Chen, DE Larson, ... New England Journal of Medicine 366 (12), 1090-1098, 2012 | 977 | 2012 |
| Bioconda: Sustainable and comprehensive software distribution for the life sciences R Dale, B Grüning, A Sjödin, J Rowe, BA Chapman, CH Tomkins-Tinch, ... Nature Methods 15 (7), 475-476, 2018 | 854 | 2018 |
| SomaticSniper: identification of somatic point mutations in whole genome sequencing data DE Larson, CC Harris, K Chen, DC Koboldt, TE Abbott, DJ Dooling, ... Bioinformatics 28 (3), 311-317, 2012 | 705 | 2012 |
| Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts S Li, D Shen, J Shao, R Crowder, W Liu, A Prat, X He, S Liu, J Hoog, C Lu, ... Cell reports 4 (6), 1116-1130, 2013 | 697 | 2013 |
| Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes TA Graubert, D Shen, L Ding, T Okeyo-Owuor, CL Lunn, J Shao, K Krysiak, ... Nature genetics 44 (1), 53-57, 2012 | 649 | 2012 |
| CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer M Griffith, NC Spies, K Krysiak, JF McMichael, AC Coffman, AM Danos, ... Nature genetics 49 (2), 170-174, 2017 | 554 | 2017 |
| DGIdb: mining the druggable genome M Griffith, OL Griffith, AC Coffman, JV Weible, JF McMichael, NC Spies, ... Nature methods 10 (12), 1209-1210, 2013 | 511 | 2013 |
