The P2X7 receptor channel: recent developments and the use of P2X7 antagonists in models of disease R Bartlett, L Stokes, R Sluyter Pharmacological Reviews 66 (3), 638-675, 2014 | 434 | 2014 |
A Glu-496 to Ala polymorphism leads to loss of function of the human P2X7 receptor BJ Gu, W Zhang, RA Worthington, R Sluyter, P Dao-Ung, S Petrou, ... Journal of Biological Chemistry 276 (14), 11135-11142, 2001 | 409 | 2001 |
A polymorphism in the P2X7 gene increases susceptibility to extrapulmonary tuberculosis SL Fernando, BM Saunders, R Sluyter, KK Skarratt, H Goldberg, ... American journal of respiratory and critical care medicine 175 (4), 360-366, 2007 | 283 | 2007 |
The human P2X7 receptor and its role in innate immunity JS Wiley, R Sluyter, BJ Gu, L Stokes, SJ Fuller Tissue Antigens 78 (5), 321-332, 2011 | 249 | 2011 |
An Ile-568 to Asn polymorphism prevents normal trafficking and function of the human P2X7 receptor JS Wiley, LP Dao-Ung, C Li, AN Shemon, BJ Gu, ML Smart, SJ Fuller, ... Journal of Biological Chemistry 278 (19), 17108-17113, 2003 | 233 | 2003 |
Inertial particle separation by differential equilibrium positions in a symmetrical serpentine micro-channel. W Li, S Yan, R Sluyter, NT Nguyen, J Zhang, G Alici Scientific Reports 4, 4527, 2014 | 230 | 2014 |
Two haplotypes of the P2X7 receptor containing the Ala‐348 to Thr polymorphism exhibit a gain‐of‐function effect and enhanced interleukin‐1β secretion L Stokes, SJ Fuller, R Sluyter, KK Skarratt, BJ Gu, JS Wiley The FASEB Journal 24 (8), 2916-2927, 2010 | 213 | 2010 |
A Thr357 to Ser polymorphism in homozygous and compound heterozygous subjects causes absent or reduced P2X7 function and impairs ATP-induced mycobacterial killing by macrophages AN Shemon, R Sluyter, SL Fernando, AL Clarke, LP Dao-Ung, KK Skarratt, ... Journal of Biological Chemistry 281 (4), 2079-2086, 2006 | 211 | 2006 |
A loss-of-function polymorphic mutation in the cytolytic P2X7 receptor gene and chronic lymphocytic leukaemia: a molecular study JS Wiley, LP Dao-Ung, BJ Gu, R Sluyter, AN Shemon, C Li, J Taper, ... The Lancet 359 (9312), 1114-1119, 2002 | 211 | 2002 |
The P2X7 receptor R Sluyter Protein Reviews: Volume 19, 17-53, 2017 | 199 | 2017 |
An Arg307 to Gln polymorphism within the ATP-binding site causes loss of function of the human P2X7 receptor BJ Gu, R Sluyter, KK Skarratt, AN Shemon, LP Dao-Ung, SJ Fuller, ... Journal of Biological Chemistry 279 (30), 31287-31295, 2004 | 193 | 2004 |
Glu496 to Ala polymorphism in the P2X7 receptor impairs ATP-induced IL-1β release from human monocytes R Sluyter, AN Shemon, JS Wiley The Journal of Immunology 172 (6), 3399-3405, 2004 | 187 | 2004 |
Significance of P2X7 receptor variants to human health and disease R Sluyter, L Stokes Recent Patents on DNA & Gene Sequences 5 (1), 41-54, 2011 | 179 | 2011 |
A loss-of-function polymorphism in the human P2X7 receptor abolishes ATP-mediated killing of mycobacteria BM Saunders, SL Fernando, R Sluyter, WJ Britton, JS Wiley The Journal of Immunology 171 (10), 5442-5446, 2003 | 158 | 2003 |
P2X7 receptor activation induces reactive oxygen species formation and cell death in murine EOC13 microglia R Bartlett, JJ Yerbury, R Sluyter Mediators of inflammation 2013 (1), 271813, 2013 | 116 | 2013 |
P2X7 receptor polymorphism impairs extracellular adenosine 5′-triphosphate-induced interleukin-18 release from human monocytes R Sluyter, JG Dalitz, JS Wiley Genes & Immunity 5 (7), 588-591, 2004 | 114 | 2004 |
Detection of P2X purinergic receptors on human B lymphocytes R Sluyter, JA Barden, JS Wiley Cell and tissue research 304, 231-236, 2001 | 98 | 2001 |
Probenecid blocks human P2X7 receptor-induced dye uptake via a pannexin-1 independent mechanism A Bhaskaracharya, P Dao-Ung, I Jalilian, M Spildrejorde, KK Skarratt, ... PloS One 9 (3), e93058, 2014 | 94 | 2014 |
Gene Dosage Determines the Negative Effects of Polymorphic Alleles of the P2X7 Receptor on Adenosine Triphosphate–Mediated Killing of Mycobacteria by … SL Fernando, BM Saunders, R Sluyter, KK Skarratt, JS Wiley, WJ Britton The Journal of infectious diseases 192 (1), 149-155, 2005 | 93 | 2005 |
Purinoceptors are involved in the induction of an osmolyte permeability in malaria‐infected and oxidized human erythrocytes V Tanneur, C Duranton, VB Brand, CD Sandu, C Akkaya, RS Kasinathan, ... The FASEB journal 20 (1), 133-135, 2006 | 92 | 2006 |