Crystal structure of a shark single-domain antibody V region in complex with lysozyme RL Stanfield, H Dooley, MF Flajnik, IA Wilson Science 305 (5691), 1770-1773, 2004 | 383 | 2004 |
Selection and characterization of naturally occurring single-domain (IgNAR) antibody fragments from immunized sharks by phage display H Dooley, MF Flajnik, AJ Porter Molecular immunology 40 (1), 25-33, 2003 | 236 | 2003 |
Antibody repertoire development in cartilaginous fish H Dooley, MF Flajnik Developmental & Comparative Immunology 30 (1-2), 43-56, 2006 | 230 | 2006 |
Shark immunity bites back: affinity maturation and memory response in the nurse shark, Ginglymostoma cirratum H Dooley, MF Flajnik European journal of immunology 35 (3), 936-945, 2005 | 198 | 2005 |
Maturation of shark single-domain (IgNAR) antibodies: evidence for induced-fit binding RL Stanfield, H Dooley, P Verdino, MF Flajnik, IA Wilson Journal of molecular biology 367 (2), 358-372, 2007 | 152 | 2007 |
First molecular and biochemical analysis of in vivo affinity maturation in an ectothermic vertebrate H Dooley, RL Stanfield, RA Brady, MF Flajnik Proceedings of the National Academy of Sciences 103 (6), 1846-1851, 2006 | 132 | 2006 |
The immunoglobulins of cold-blooded vertebrates R Pettinello, H Dooley Biomolecules 4 (4), 1045-1069, 2014 | 81 | 2014 |
Isolation and characterisation of Ebolavirus-specific recombinant antibody fragments from murine and shark immune libraries SA Goodchild, H Dooley, RJ Schoepp, M Flajnik, SG Lonsdale Molecular immunology 48 (15-16), 2027-2037, 2011 | 76 | 2011 |
Diversity and repertoire of IgW and IgM VH families in the newborn nurse shark LL Rumfelt, RL Lohr, H Dooley, MF Flajnik BMC immunology 5, 1-15, 2004 | 74 | 2004 |
Stabilization of antibody fragments in adverse environments H Dooley, SD Grant, WJ Harris, AJ Porter Biotechnology and applied biochemistry 28 (1), 77-83, 1998 | 68 | 1998 |
Discovery of all three types in cartilaginous fishes enables phylogenetic resolution of the origins and evolution of interferons AK Redmond, J Zou, CJ Secombes, DJ Macqueen, H Dooley Frontiers in immunology 10, 1558, 2019 | 64 | 2019 |
The CXC chemokine receptors of fish: insights into CXCR evolution in the vertebrates J Zou, AK Redmond, Z Qi, H Dooley, CJ Secombes General and Comparative Endocrinology 215, 117-131, 2015 | 56 | 2015 |
Shark IgNAR-derived binding domains as potential diagnostic and therapeutic agents H Matz, H Dooley Developmental & Comparative Immunology 90, 100-107, 2019 | 49 | 2019 |
Characterization of the immunoglobulin repertoire of the spiny dogfish (Squalus acanthias) LE Smith, K Crouch, W Cao, MR Müller, L Wu, J Steven, M Lee, M Liang, ... Developmental & Comparative Immunology 36 (4), 665-679, 2012 | 47 | 2012 |
Antigen binding domains H Dooley, A Porter, M Flajnik US Patent App. 10/486,608, 2005 | 45 | 2005 |
Humoral immune response of the small-spotted catshark, Scyliorhinus canicula K Crouch, LE Smith, R Williams, W Cao, M Lee, A Jensen, H Dooley Fish & shellfish immunology 34 (5), 1158-1169, 2013 | 42 | 2013 |
Generation and isolation of target-specific single-domain antibodies from shark immune repertoires MR Müller, R O’Dwyer, M Kovaleva, F Rudkin, H Dooley, CJ Barelle Antibody Engineering: Methods and Protocols, Second Edition, 177-194, 2012 | 36 | 2012 |
Noncoordinate expression of J‐chain and B limp‐1 define nurse shark plasma cell populations during ontogeny CD Castro, Y Ohta, H Dooley, MF Flajnik European journal of immunology 43 (11), 3061-3075, 2013 | 34 | 2013 |
Emergence of the acute-phase protein hemopexin in jawed vertebrates H Dooley, EB Buckingham, MF Criscitiello, MF Flajnik Molecular immunology 48 (1-3), 147-152, 2010 | 34 | 2010 |
The whale shark genome reveals patterns of vertebrate gene family evolution M Tan, AK Redmond, H Dooley, R Nozu, K Sato, S Kuraku, S Koren, ... Elife 10, e65394, 2021 | 28 | 2021 |