antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters T Weber, K Blin, S Duddela, D Krug, HU Kim, R Bruccoleri, SY Lee, ... Nucleic acids research 43 (W1), W237-W243, 2015 | 2065 | 2015 |
Minimum information about a biosynthetic gene cluster MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ... Nature chemical biology 11 (9), 625-631, 2015 | 889 | 2015 |
Complete genome sequence of the myxobacterium Sorangium cellulosum S Schneiker, O Perlova, O Kaiser, K Gerth, A Alici, MO Altmeyer, D Bartels, ... Nature biotechnology 25 (11), 1281-1289, 2007 | 486 | 2007 |
Genes and Enzymes Involved in Caffeic Acid Biosynthesis in the Actinomycete Saccharothrix espanaensis M Berner, D Krug, C Bihlmaier, A Vente, R Müller, A Bechthold Journal of bacteriology 188 (7), 2666-2673, 2006 | 208 | 2006 |
Correlating chemical diversity with taxonomic distance for discovery of natural products in myxobacteria T Hoffmann, D Krug, N Bozkurt, S Duddela, R Jansen, R Garcia, K Gerth, ... Nature communications 9 (1), 803, 2018 | 188 | 2018 |
Discovering the Hidden Secondary Metabolome of Myxococcus xanthus: a Study of Intraspecific Diversity D Krug, G Zurek, O Revermann, M Vos, GJ Velicer, R Müller Applied and environmental microbiology 74 (10), 3058-3068, 2008 | 178 | 2008 |
Myxovirescin A Biosynthesis is Directed by Hybrid Polyketide Synthases/Nonribosomal Peptide Synthetase, 3‐Hydroxy‐3‐Methylglutaryl–CoA Synthases, and trans‐Acting Acyltransferases V Simunovic, J Zapp, S Rachid, D Krug, P Meiser, R Müller ChemBioChem 7 (8), 1206-1220, 2006 | 174 | 2006 |
Secondary metabolomics: the impact of mass spectrometry-based approaches on the discovery and characterization of microbial natural products D Krug, R Müller Natural Product Reports 31 (6), 768-783, 2014 | 172 | 2014 |
Compendium of specialized metabolite biosynthetic diversity encoded in bacterial genomes A Gavriilidou, SA Kautsar, N Zaburannyi, D Krug, R Müller, MH Medema, ... Nature microbiology 7 (5), 726-735, 2022 | 163 | 2022 |
Myxoprincomide: a natural product from Myxococcus xanthus discovered by comprehensive analysis of the secondary metabolome NS Cortina, D Krug, A Plaza, O Revermann, R Müller Angewandte Chemie International Edition 51 (3), 811-816, 2012 | 141 | 2012 |
Molecular and biochemical studies of chondramide formation—highly cytotoxic natural products from Chondromyces crocatus Cm c5 S Rachid, D Krug, B Kunze, I Kochems, M Scharfe, TM Zabriskie, ... Chemistry & biology 13 (6), 667-681, 2006 | 129 | 2006 |
Bacteria as genetically programmable producers of bioactive natural products JJ Hug, D Krug, R Müller Nature Reviews Chemistry 4 (4), 172-193, 2020 | 114 | 2020 |
Improving natural products identification through targeted LC-MS/MS in an untargeted secondary metabolomics workflow T Hoffmann, D Krug, S Hüttel, R Müller Analytical chemistry 86 (21), 10780-10788, 2014 | 114 | 2014 |
Reconstitution of the Myxothiazol Biosynthetic Gene Cluster by Red/ET Recombination and Heterologous Expression in Myxococcus xanthus O Perlova, J Fu, S Kuhlmann, D Krug, AF Stewart, Y Zhang, R Müller Applied and Environmental Microbiology 72 (12), 7485-7494, 2006 | 110 | 2006 |
Self-resistance guided genome mining uncovers new topoisomerase inhibitors from myxobacteria F Panter, D Krug, S Baumann, R Müller Chemical science 9 (21), 4898-4908, 2018 | 101 | 2018 |
Discovering natural products from myxobacteria with emphasis on rare producer strains in combination with improved analytical methods RO Garcia, D Krug, R Müller Methods in Enzymology 458, 59-91, 2009 | 88 | 2009 |
Efficient mining of myxobacterial metabolite profiles enabled by liquid chromatography–electrospray ionisation-time-of-flight mass spectrometry and compound-based principal … D Krug, G Zurek, B Schneider, R Garcia, R Müller Analytica chimica acta 624 (1), 97-106, 2008 | 82 | 2008 |
DKxanthene biosynthesis—Understanding the basis for diversity-oriented synthesis in myxobacterial secondary metabolism P Meiser, KJ Weissman, HB Bode, D Krug, JS Dickschat, A Sandmann, ... Chemistry & biology 15 (8), 771-781, 2008 | 81 | 2008 |
Discovery of additional members of the tyrosine aminomutase enzyme family and the mutational analysis of CmdF D Krug, R Müller ChemBioChem 10 (4), 741-750, 2009 | 74 | 2009 |
Biosynthesis of (R)-β-tyrosine and its incorporation into the highly cytotoxic chondramides produced by Chondromyces crocatus S Rachid, D Krug, KJ Weissman, R Muller Journal of Biological Chemistry 282 (30), 21810-21817, 2007 | 71 | 2007 |