| Opportunities and challenges for combining chemo-and biocatalysis F Rudroff, MD Mihovilovic, H Gröger, R Snajdrova, H Iding, ... Nature Catalysis 1 (1), 12-22, 2018 | 572 | 2018 |
| Identification of (S)-selective transaminases for the asymmetric synthesis of bulky chiral amines IV Pavlidis, MS Weiß, M Genz, P Spurr, SP Hanlon, B Wirz, H Iding, ... Nature chemistry 8 (11), 1076-1082, 2016 | 236 | 2016 |
| Benzoylformate decarboxylase from Pseudomonas putida as stable catalyst for the synthesis of chiral 2‐hydroxy ketones H Iding, T Dünnwald, L Greiner, A Liese, M Müller, P Siegert, J Grötzinger, ... Chemistry–A European Journal 6 (8), 1483-1495, 2000 | 208 | 2000 |
| The synthetic development of the anti-influenza neuraminidase inhibitor oseltamivir phosphate (Tamiflu®): a challenge for synthesis & process research S Abrecht, P Harrington, H Iding, M Karpf, R Trussardi, B Wirz, U Zutter Chimia 58 (9), 621-621, 2004 | 180 | 2004 |
| Application of α-keto acid decarboxylases in biotransformations H Iding, P Siegert, K Mesch, M Pohl Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1998 | 147 | 1998 |
| Asymmetric reductive amination of ketones catalyzed by imine reductases D Wetzl, M Gand, A Ross, H Müller, P Matzel, SP Hanlon, M Müller, B Wirz, ... ChemCatChem 8 (12), 2023-2026, 2016 | 136 | 2016 |
| Expanding the imine reductase toolbox by exploring the bacterial protein‐sequence space D Wetzl, M Berrera, N Sandon, D Fishlock, M Ebeling, M Müller, S Hanlon, ... ChemBioChem 16 (12), 1749-1756, 2015 | 133 | 2015 |
| New, Efficient Synthesis of Oseltamivir Phosphate (Tamiflu) via Enzymatic Desymmetrization of a meso-1,3-Cyclohexanedicarboxylic Acid Diester U Zutter, H Iding, P Spurr, B Wirz The Journal of organic chemistry 73 (13), 4895-4902, 2008 | 125 | 2008 |
| Asymmetric benzoin reaction catalyzed by benzoylformate decarboxylase AS Demir, T Dünnwald, H Iding, M Pohl, M Müller Tetrahedron: Asymmetry 10 (24), 4769-4774, 1999 | 117 | 1999 |
| Exchanging the substrate specificities of pyruvate decarboxylase from Zymomonas mobilis and benzoylformate decarboxylase from Pseudomonas putida P Siegert, MJ McLeish, M Baumann, H Iding, MM Kneen, GL Kenyon, ... Protein Engineering Design and Selection 18 (7), 345-357, 2005 | 110 | 2005 |
| Amine transaminase engineering for spatially bulky substrate acceptance MS Weiß, IV Pavlidis, P Spurr, SP Hanlon, B Wirz, H Iding, ... ChemBioChem 18 (11), 1022-1026, 2017 | 56 | 2017 |
| Protein-engineering of an amine transaminase for the stereoselective synthesis of a pharmaceutically relevant bicyclic amine MS Weiß, IV Pavlidis, P Spurr, SP Hanlon, B Wirz, H Iding, ... Organic & biomolecular chemistry 14 (43), 10249-10254, 2016 | 55 | 2016 |
| The organic–synthetic potential of recombinant ene reductases: substrate‐scope evaluation and process optimization T Reß, W Hummel, SP Hanlon, H Iding, H Gröger ChemCatChem 7 (8), 1302-1311, 2015 | 51 | 2015 |
| Isopropylamine as amine donor in transaminase‐catalyzed reactions: better acceptance through reaction and enzyme engineering AWH Dawood, MS Weiß, C Schulz, IV Pavlidis, H Iding, ROMA de Souza, ... ChemCatChem 10 (18), 3943-3949, 2018 | 50 | 2018 |
| Extended catalytic scope of a well‐known enzyme: asymmetric reduction of iminium substrates by glucose dehydrogenase S Roth, A Präg, C Wechsler, M Marolt, S Ferlaino, S Lüdeke, N Sandon, ... ChemBioChem 18 (17), 1703-1706, 2017 | 50 | 2017 |
| Identification of potent and selective cathepsin S inhibitors containing different central cyclic scaffolds H Hilpert, H Mauser, R Humm, L Anselm, H Kuehne, G Hartmann, ... Journal of Medicinal Chemistry 56 (23), 9789-9801, 2013 | 42 | 2013 |
| Asymmetric synthesis of Akt kinase inhibitor ipatasertib C Han, S Savage, M Al-Sayah, H Yajima, T Remarchuk, R Reents, B Wirz, ... Organic letters 19 (18), 4806-4809, 2017 | 37 | 2017 |
| Separation of pyrrolidine allylation products by diastereoselective enzymatic ester hydrolysis VK Aggarwal, CJ Astle, H Iding, B Wirz, M Rogers-Evans Tetrahedron letters 46 (6), 945-947, 2005 | 34 | 2005 |
| Multiselective enzymatic reactions for the synthesis of protected homochiral cis-and trans-1, 3, 5-cyclohexanetriols B Wirz, H Iding, H Hilpert Tetrahedron: Asymmetry 11 (20), 4171-4178, 2000 | 32 | 2000 |
| Identification and preclinical development of a 2, 5, 6-trisubstituted fluorinated pyridine derivative as a radioligand for the positron emission tomography imaging of … A Haider, L Gobbi, J Kretz, C Ullmer, A Brink, M Honer, TJ Woltering, ... Journal of medicinal chemistry 63 (18), 10287-10306, 2020 | 29 | 2020 |
