Enhanced glutathione PEGylated liposomal brain delivery of an anti-amyloid single domain antibody fragment in a mouse model for Alzheimer's disease M Rotman, MM Welling, A Bunschoten, ME de Backer, J Rip, ... Journal of Controlled Release 203, 40-50, 2015 | 162 | 2015 |
Progress toward long-term survivors of glioblastoma JN Cantrell, MR Waddle, M Rotman, JL Peterson, H Ruiz-Garcia, ... Mayo clinic proceedings 94 (7), 1278-1286, 2019 | 99 | 2019 |
Fusion of hIgG1-Fc to 111In-anti-amyloid single domain antibody fragment VHH-pa2H prolongs blood residential time in APP/PS1 mice but does not increase brain uptake M Rotman, MM Welling, ML van den Boogaard, LG Moursel, ... Nuclear medicine and biology 42 (8), 695-702, 2015 | 61 | 2015 |
In vivo detection of amyloid-β deposits using heavy chain antibody fragments in a transgenic mouse model for Alzheimer's disease RJA Nabuurs, KS Rutgers, MM Welling, A Metaxas, ME De Backer, ... PLoS One 7 (6), e38284, 2012 | 54 | 2012 |
Transmigration of beta amyloid specific heavy chain antibody fragments across the in vitro blood–brain barrier KS Rutgers, RJA Nabuurs, SAA Van den Berg, GJ Schenk, M Rotman, ... Neuroscience 190, 37-42, 2011 | 53 | 2011 |
Camelid heavy chain only antibody fragment domain against β‐site of amyloid precursor protein cleaving enzyme 1 inhibits β‐secretase activity in vitro and in vivo B Dorresteijn, M Rotman, D Faber, R Schravesande, E Suidgeest, ... The FEBS Journal 282 (18), 3618-3631, 2015 | 22 | 2015 |
Pre-clinical optical imaging and MRI for drug development in Alzheimer's disease M Rotman, TJA Snoeks, L van der Weerd Drug Discovery Today: Technologies 8 (2-4), e117-e125, 2011 | 9 | 2011 |
SorCS1 binds the insulin receptor to enhance insulin sensitivity M Kjolby, KM Pedersen, P Breining, N Wellner, KMJ Sørensen, DM Vittrup, ... bioRxiv, 2020.11. 10.376178, 2020 | 1 | 2020 |
411 The Hatchery, a Universal Approach for Incubator Space in Academia R Hale, M Rotman, A Sreedhar, S Ekker Journal of Clinical and Translational Science 7 (s1), 123-123, 2023 | | 2023 |
Soluble SorCS1 binds the insulin receptor to enhance insulin sensitivity M Kjolby, P Breining, K Pedersen, N Wellner, K Sørensen, A Gjessing, ... | | 2022 |
STEM-03. FOCAL ENHANCED DELIVERY OF SYSTEMICALLY ADMINISTERED THERAPEUTIC HUMAN MESENCHYMAL STEM CELLS USING MRI-GUIDED DISRUPTION OF THE BBB WITH FOCUSED ULTRASOUND R Al-Kharboosh, N Ellens, K Cheng, M Rotman, J Green, ... Neuro-Oncology 19 (Suppl 6), vi227, 2017 | | 2017 |
385 Focal Enhanced Delivery of Systemically Administered Therapeutic Human Mesenchymal Stem Cells Using MRI-guided Disruption of the BBB with Focused Ultrasound R Al-Kharboosh, N Ellens, K Cheng, M Rotman, J Green, ... Neurosurgery 64 (CN_suppl_1), 292, 2017 | | 2017 |
Optimized delivery of an anti-amyloid VHH-2H heavy chain antibody fragment to the mouse brain MM Welling, M Rotman, ME de Backer, J Rip, PJ Gaillard European Journal of Nuclear Medicine and Molecular Imaging 40, S128-S128, 2013 | | 2013 |
Crossing barriers, delivery of llama antibody fragments into the brain M Rotman Signal 15 (5), 1167-1178, 2011 | | 2011 |