AMPK maintains energy homeostasis and survival in cancer cells via regulating p38/PGC-1α-mediated mitochondrial biogenesis Chaube B, Malvi P, Singh SV, Mohammad N, Viollet B, Bhat MK Cell Death and Discovery 10, 2015 | 151* | 2015 |
Cholesterol depletion by methyl-β-cyclodextrin augments tamoxifen induced cell death by enhancing its uptake in melanoma N Mohammad, P Malvi, AS Meena, SV Singh, B Chaube, ... Molecular cancer 13, 1-13, 2014 | 127 | 2014 |
Strategy to enhance efficacy of doxorubicin in solid tumor cells by methyl-β-cyclodextrin: Involvement of p53 and Fas receptor ligand complex N Mohammad, S Vikram Singh, P Malvi, B Chaube, D Athavale, ... Scientific reports 5 (1), 11853, 2015 | 93 | 2015 |
Inherent and acquired resistance to paclitaxel in hepatocellular carcinoma: molecular events involved AS Meena, A Sharma, R Kumari, N Mohammad, SV Singh, MK Bhat PLoS One 8 (4), e61524, 2013 | 92 | 2013 |
Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression. Balkrishna Chaube, Parmanand Malvi, Singh S Vikram, Naoshad Mohammad, Meena ... Oncotarget 6 (35), 37281-37299, 2015 | 79 | 2015 |
Obesity induced rapid melanoma progression is reversed by orlistat treatment and dietary intervention: role of adipokines P Malvi, B Chaube, V Pandey, MV Vijayakumar, PR Boreddy, ... Molecular Oncology 9 (3), 689-703, 2015 | 70 | 2015 |
Elevated circulatory levels of leptin and resistin impair therapeutic efficacy of dacarbazine in melanoma under obese state P Malvi, B Chaube, SV Singh, N Mohammad, MV Vijayakumar, S Singh, ... Cancer & metabolism 6, 1-14, 2018 | 53 | 2018 |
Weight control interventions improve therapeutic efficacy of dacarbazine in melanoma by reversing obesity-induced drug resistance PM , Balkrishna Chaube , Shivendra Vikram Singh , Naoshad Mohammad , Vimal ... Cancer & Metabolism 4 (21), 10.1186/s40170-016-0162-8, 2016 | 52* | 2016 |
Targeting the spliceosome through RBM39 degradation results in exceptional responses in high-risk neuroblastoma models S Singh, W Quarni, M Goralski, S Wan, H Jin, LA Van de Velde, J Fang, ... Science advances 7 (47), eabj5405, 2021 | 43 | 2021 |
Proteasomal inhibition sensitizes cervical cancer cells to mitomycin C-induced bystander effect: the role of tumor microenvironment SV Singh, AK Ajay, N Mohammad, P Malvi, B Chaube, AS Meena, MK Bhat Cell death & disease 6 (10), e1934, 2015 | 36 | 2015 |
KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma A D’Oto, J Fang, H Jin, B Xu, S Singh, A Mullasseril, V Jones, A Abu-Zaid, ... Nature Communications 12 (1), 7204, 2021 | 27 | 2021 |
Metformin induced lactic acidosis impaired response of cancer cells towards paclitaxel and doxorubicin: Role of monocarboxylate transporter SV Singh, B Chaube, SS Mayengbam, A Singh, P Malvi, N Mohammad, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1867 (3), 166011, 2021 | 20 | 2021 |
Targeting KDM4 for treating PAX3-FOXO1–driven alveolar rhabdomyosarcoma S Singh, A Abu-Zaid, H Jin, J Fang, Q Wu, T Wang, H Feng, W Quarni, ... Science translational medicine 14 (653), eabq2096, 2022 | 18 | 2022 |
Genome-wide mapping of cancer dependency genes and genetic modifiers of chemotherapy in high-risk hepatoblastoma J Fang, S Singh, C Cheng, S Natarajan, H Sheppard, A Abu-Zaid, ... Nature Communications 14 (1), 4003, 2023 | 10 | 2023 |
17-DMAG dually inhibits Hsp90 and histone lysine demethylases in alveolar rhabdomyosarcoma S Singh, A Abu-Zaid, W Lin, J Low, A Abdolvahabi, H Jin, Q Wu, B Cooke, ... Iscience, 2020 | 8 | 2020 |
The Oligostilbene Gnetin H Is a Novel Glycolysis Inhibitor That Regulates Thioredoxin Interacting Protein Expression and Synergizes with OXPHOS Inhibitor in Cancer Cells S Singh, F De Carlo, MA Ibrahim, P Penfornis, AJ Mouton, SK Tripathi, ... International Journal of Molecular Sciences 24 (9), 7741, 2023 | 4 | 2023 |
Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing is associated with therapeutic response to splicing inhibitor C Jablonowski, W Quarni, S Singh, H Tan, DH Bostanthirige, H Jin, ... eLife, 12:RP90993, 2023 | 3 | 2023 |
A CRISPR-drug perturbational map for identifying compounds to combine with commonly used chemotherapeutics HM Lee, WC Wright, M Pan, J Low, D Currier, J Fang, S Singh, S Nance, ... Nature Communications 14 (1), 7332, 2023 | 2 | 2023 |
The context-dependent epigenetic and organogenesis programs determine 3D vs. 2D cellular fitness of MYC-driven cancer JF Shivendra Singh, Brennan Wells, Qiong Wu, Jun Yang Research square, https://doi.org/10.21203/rs.3.rs-4390765, 2024 | | 2024 |
Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma JY Ahmed Abu-Zaid, Shivendra Singh, Hongjian Jin, Jie Fang, Qiong Wu Cell reports Medicine 5 (3), 101468,, 2024 | | 2024 |