Properties of neuronal nicotinic acetylcholine receptors: pharmacological characterization and modulation of synaptic function EX Albuquerque, M Alkondon, EFR Pereira, NG Castro, A Schrattenholz, ... Journal of Pharmacology and Experimental Therapeutics 280 (3), 1117-1136, 1997 | 567 | 1997 |
alpha-Bungarotoxin-sensitive hippocampal nicotinic receptor channel has a high calcium permeability NG Castro, EX Albuquerque Biophysical journal 68 (2), 516-524, 1995 | 336 | 1995 |
Astrocyte-induced synaptogenesis is mediated by transforming growth factor β signaling through modulation of D-serine levels in cerebral cortex neurons LP Diniz, JC Almeida, V Tortelli, CV Lopes, P Setti-Perdigão, J Stipursky, ... Journal of Biological Chemistry 287 (49), 41432-41445, 2012 | 247 | 2012 |
Nicotinic receptor function in the mammalian central nervous system. EX Albuquerque, EF Pereira, NG Castro, M Alkondon, S Reinhardt, ... Annals of the New York Academy of Sciences 757, 48-72, 1995 | 217 | 1995 |
Altered oxygen metabolism associated to neurogenesis of induced pluripotent stem cells derived from a schizophrenic patient B da Silveira Paulsen, R de Moraes Maciel, A Galina, MS Da Silveira, ... Cell transplantation 21 (7), 1547-1559, 2012 | 166 | 2012 |
Choline and acetylcholine have similar kinetic properties of activation and desensitization on the α7 nicotinic receptors in rat hippocampal neurons A Mike, NG Castro, EX Albuquerque Brain research 882 (1-2), 155-168, 2000 | 165 | 2000 |
Colchicine inhibits cationic dye uptake induced by ATP in P2X2 and P2X7 receptor‐expressing cells: implications for its therapeutic action C Marques‐da‐Silva, MM Chaves, NG Castro, R Coutinho‐Silva, ... British journal of pharmacology 163 (5), 912-926, 2011 | 161 | 2011 |
Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice CP Figueiredo, FGQ Barros-Aragão, RLS Neris, PS Frost, C Soares, ... Nature communications 10 (1), 3890, 2019 | 154 | 2019 |
Design, Synthesis, and Pharmacological Profile of Novel Fused Pyrazolo[4,3-d]pyridine and Pyrazolo[3,4-b][1,8]naphthyridine Isosteres: A New Class of Potent … EJ Barreiro, CA Camara, H Verli, L Brazil-Más, NG Castro, WM Cintra, ... Journal of medicinal chemistry 46 (7), 1144-1152, 2003 | 144 | 2003 |
Synthesis and preliminary pharmacological evaluation of new (±) 1, 4-naphthoquinones structurally related to lapachol AJM da Silva, CD Buarque, FV Brito, L Aurelian, LF Macedo, LH Malkas, ... Bioorganic & medicinal chemistry 10 (8), 2731-2738, 2002 | 114 | 2002 |
Astrocyte transforming growth factor beta 1 promotes inhibitory synapse formation via CaM kinase II signaling LP Diniz, V Tortelli, MN Garcia, APB Araújo, HM Melo, GS Seixas da Silva, ... Glia 62 (12), 1917-1931, 2014 | 113 | 2014 |
Cardanol-derived AChE inhibitors: Towards the development of dual binding derivatives for Alzheimer's disease LFN Lemes, G de Andrade Ramos, AS De Oliveira, FMR Da Silva, ... European Journal of Medicinal Chemistry 108, 687-700, 2016 | 99 | 2016 |
Brief-lifetime, fast-inactivating ion channels account for the α-bungarotoxin-sensitive nicotinic response in hippocampal neurons NG Castro, EX Albuquerque Neuroscience letters 164 (1-2), 137-140, 1993 | 94 | 1993 |
Design, synthesis and evaluation of novel feruloyl-donepezil hybrids as potential multitarget drugs for the treatment of Alzheimer's disease KST Dias, CT de Paula, T Dos Santos, INO Souza, MS Boni, ... European journal of medicinal chemistry 130, 440-457, 2017 | 87 | 2017 |
New selective acetylcholinesterase inhibitors designed from natural piperidine alkaloids C Viegas Jr, VS Bolzani, LSB Pimentel, NG Castro, RF Cabral, RS Costa, ... Bioorganic & medicinal chemistry 13 (13), 4184-4190, 2005 | 85 | 2005 |
Direct inhibition of the N‐methyl‐D‐aspartate receptor channel by dopamine and (+)‐SKF38393 NG Castro, MCF De Mello, FG De Mello, Y Aracava British journal of pharmacology 126 (8), 1847-1855, 1999 | 82 | 1999 |
Geissospermum vellosii stembark: anticholinesterase activity and improvement of scopolamine-induced memory deficits JA Lima, RS Costa, RA Epifânio, NG Castro, MS Rocha, AC Pinto Pharmacology biochemistry and behavior 92 (3), 508-513, 2009 | 70 | 2009 |
New potential AChE inhibitor candidates AAN De Paula, JBL Martins, ML Dos Santos, LC Nascente, LAS Romeiro, ... European Journal of Medicinal Chemistry 44 (9), 3754-3759, 2009 | 65 | 2009 |
A novel agonist binding site on nicotinic acetylcholine receptors EFR Pereira, M Alkondon, T Tano, NG Castro, MM Fróes-Ferra¯ o, ... Journal of receptor research 13 (1-4), 413-436, 1993 | 62 | 1993 |
Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer … FPD Viegas, M de Freitas Silva, MD da Rocha, MR Castelli, MM Riquiel, ... European Journal of Medicinal Chemistry 147, 48-65, 2018 | 57 | 2018 |