| Applications of deuterium in medicinal chemistry T Pirali, M Serafini, S Cargnin, AA Genazzani Journal of medicinal chemistry 62 (11), 5276-5297, 2019 | 558 | 2019 |
| A primer of deuterium in drug design S Cargnin, M Serafini, T Pirali Future Medicinal Chemistry 11 (16), 2039-2042, 2019 | 90 | 2019 |
| Discovery of highly potent benzimidazole derivatives as indoleamine 2, 3-dioxygenase-1 (IDO1) inhibitors: from structure-based virtual screening to in vivo pharmacodynamic activity M Serafini, E Torre, S Aprile, ED Grosso, A Gesù, A Griglio, G Colombo, ... Journal of medicinal chemistry 63 (6), 3047-3065, 2020 | 51 | 2020 |
| Targeting transient receptor potential vanilloid 1 (TRPV1) channel softly: The discovery of passerini adducts as a topical treatment for inflammatory skin disorders M Serafini, A Griglio, S Aprile, F Seiti, C Travelli, F Pattarino, G Grosa, ... Journal of medicinal chemistry 61 (10), 4436-4455, 2018 | 38 | 2018 |
| Essential medicinal chemistry of essential medicines M Serafini, S Cargnin, A Massarotti, T Pirali, AA Genazzani Journal of medicinal chemistry 63 (18), 10170-10187, 2020 | 36 | 2020 |
| Pyrtriazoles, a novel class of store-operated calcium entry modulators: discovery, biological profiling, and in vivo proof-of-concept efficacy in acute pancreatitis B Riva, A Griglio, M Serafini, C Cordero-Sanchez, S Aprile, R Di Paola, ... Journal of medicinal chemistry 61 (21), 9756-9783, 2018 | 30 | 2018 |
| A multicomponent approach in the discovery of indoleamine 2, 3-dioxygenase 1 inhibitors: Synthesis, biological investigation and docking studies A Griglio, E Torre, M Serafini, A Bianchi, R Schmid, GC Zabetta, ... Bioorganic & Medicinal Chemistry Letters 28 (4), 651-657, 2018 | 30 | 2018 |
| Click 1, 2, 3-triazoles in drug discovery and development: From the flask to the clinic? M Serafini, T Pirali, GC Tron Advances in Heterocyclic Chemistry 134, 101-148, 2021 | 29 | 2021 |
| N-heterocyclic carbene catalyzed deuteration of aldehydes in D2O Y Sawama, Y Miki, H Sajiki Synlett 31 (07), 699-702, 2020 | 25 | 2020 |
| A versatile and sustainable multicomponent platform for the synthesis of protein degraders: proof-of-concept application to BRD4-degrading PROTACs IP Bhela, A Ranza, FC Balestrero, M Serafini, S Aprile, RMC Di Martino, ... Journal of Medicinal Chemistry 65 (22), 15282-15299, 2022 | 23 | 2022 |
| Synthesis, docking and biological evaluation of a novel class of imidazothiazoles as IDO1 inhibitors M Serafini, E Torre, S Aprile, A Massarotti, S Fallarini, T Pirali Molecules 24 (10), 1874, 2019 | 23 | 2019 |
| Identification of a potent phosphoinositide 3‐kinase pan inhibitor displaying a strategic carboxylic acid group and development of its prodrugs T Pirali, E Ciraolo, S Aprile, A Massarotti, A Berndt, A Griglio, M Serafini, ... ChemMedChem 12 (18), 1542-1554, 2017 | 22 | 2017 |
| The 115 years old multicomponent Bargellini reaction: perspectives and new applications M Serafini, I Murgia, M Giustiniano, T Pirali, GC Tron Molecules 26 (3), 558, 2021 | 21 | 2021 |
| A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability M Nikolaeva-Koleva, L Butron, S González-Rodríguez, I Devesa, ... Scientific Reports 11 (1), 246, 2021 | 20 | 2021 |
| Store-operated calcium entry as a therapeutic target in acute pancreatitis: discovery and development of drug-like SOCE inhibitors M Serafini, C Cordero-Sanchez, R Di Paola, IP Bhela, S Aprile, B Purghè, ... Journal of Medicinal Chemistry 63 (23), 14761-14779, 2020 | 18 | 2020 |
| What’s in a name? Drug nomenclature and medicinal chemistry trends using INN publications M Serafini, S Cargnin, A Massarotti, GC Tron, T Pirali, AA Genazzani Journal of Medicinal Chemistry 64 (8), 4410-4429, 2021 | 15 | 2021 |
| Soft drugs for dermatological applications: recent trends S Aprile, M Serafini, T Pirali Drug discovery today 24 (12), 2234-2246, 2019 | 12 | 2019 |
| STIM1 and ORAI1 mutations leading to tubular aggregate myopathies are sensitive to the Store-operated Ca2+-entry modulators CIC-37 and CIC-39 B Riva, E Pessolano, E Quaglia, C Cordero-Sanchez, IP Bhela, A Topf, ... Cell Calcium 105, 102605, 2022 | 9 | 2022 |
| Tritylamine as an ammonia surrogate in the Ugi reaction provides access to unprecedented 5-sulfamido oxazoles using Burgess-type reagents IP Bhela, M Serafini, E Del Grosso, GC Tron, T Pirali Organic Letters 23 (9), 3610-3614, 2021 | 9 | 2021 |
| An unexpected deuterium-induced metabolic switch in doxophylline S Aprile, G Colombo, M Serafini, R Di Paola, F Pisati, IP Bhela, ... ACS Medicinal Chemistry Letters 13 (8), 1278-1285, 2022 | 8 | 2022 |
