Design, synthesis, and biological evaluation of aryloxyethyl thiocyanate derivatives against Trypanosoma cruzi E Elhalem, BN Bailey, R Docampo, I Ujváry, SH Szajnman, JB Rodriguez Journal of medicinal chemistry 45 (18), 3984-3999, 2002 | 179 | 2002 |
Synthesis and biological evaluation of 1-amino-1, 1-bisphosphonates derived from fatty acids against Trypanosoma cruzi targeting farnesyl pyrophosphate synthase SH Szajnman, EL Ravaschino, R Docampo, JB Rodriguez Bioorganic & medicinal chemistry letters 15 (21), 4685-4690, 2005 | 110 | 2005 |
Bisphosphonates derived from fatty acids are potent inhibitors of Trypanosoma cruzi farnesyl pyrophosphate synthase SH Szajnman, A Montalvetti, Y Wang, R Docampo, JB Rodriguez Bioorganic & medicinal chemistry letters 13 (19), 3231-3235, 2003 | 106 | 2003 |
Design and synthesis of aryloxyethyl thiocyanate derivatives as potent inhibitors of Trypanosoma cruzi proliferation SH Szajnman, W Yan, BN Bailey, R Docampo, E Elhalem, JB Rodriguez Journal of medicinal chemistry 43 (9), 1826-1840, 2000 | 103 | 2000 |
Synthesis and biological evaluation of 2-alkylaminoethyl-1, 1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase SH Szajnman, GE Garcı, ZH Li, C Jiang, M Galizzi, EJ Bontempi, ... Bioorganic & medicinal chemistry 16 (6), 3283-3290, 2008 | 82 | 2008 |
New antibacterials for the treatment of toxoplasmosis; a patent review JB Rodriguez, SH Szajnman Expert Opinion on Therapeutic Patents 22 (3), 311-333, 2012 | 79 | 2012 |
Bisphosphonates derived from fatty acids are potent growth inhibitors of Trypanosoma cruzi SH Szajnman, BN Bailey, R Docampo, JB Rodriguez Bioorganic & medicinal chemistry letters 11 (6), 789-792, 2001 | 73 | 2001 |
Structure−Activity Relationship of New Growth Inhibitors of Trypanosoma cruzi GM Cinque, SH Szajnman, L Zhong, R Docampo, AJ Schvartzapel, ... Journal of medicinal chemistry 41 (9), 1540-1554, 1998 | 72 | 1998 |
Design, synthesis and biological evaluation of sulfur-containing 1, 1-bisphosphonic acids as antiparasitic agents M Recher, AP Barboza, ZH Li, M Galizzi, M Ferrer-Casal, SH Szajnman, ... European journal of medicinal chemistry 60, 431-440, 2013 | 66 | 2013 |
Synthesis and biological evaluation of new 2-alkylaminoethyl-1, 1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase VS Rosso, SH Szajnman, L Malayil, M Galizzi, SNJ Moreno, R Docampo, ... Bioorganic & medicinal chemistry 19 (7), 2211-2217, 2011 | 62 | 2011 |
New inhibitor targeting Acyl-CoA synthetase 4 reduces breast and prostate tumor growth, therapeutic resistance and steroidogenesis AF Castillo, UD Orlando, PM Maloberti, JG Prada, MA Dattilo, AR Solano, ... Cellular and Molecular Life Sciences 78, 2893-2910, 2021 | 45 | 2021 |
Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1, 1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase S Aripirala, SH Szajnman, J Jakoncic, JB Rodriguez, R Docampo, ... Journal of medicinal chemistry 55 (14), 6445-6454, 2012 | 41 | 2012 |
Approaches for designing new potent inhibitors of farnesyl pyrophosphate synthase JB Rodriguez, BN Falcone, SH Szajnman Expert Opinion on Drug Discovery 11 (3), 307-320, 2016 | 40 | 2016 |
Selenium-containing analogues of WC-9 are extremely potent inhibitors of Trypanosoma cruzi proliferation MN Chao, M Storey, C Li, MG Rodríguez, F Di Salvo, SH Szajnman, ... Bioorganic & medicinal chemistry 25 (24), 6435-6449, 2017 | 35 | 2017 |
New insights into molecular recognition of 1, 1-bisphosphonic acids by farnesyl diphosphate synthase M Ferrer-Casal, C Li, M Galizzi, CA Stortz, SH Szajnman, R Docampo, ... Bioorganic & medicinal chemistry 22 (1), 398-405, 2014 | 31 | 2014 |
1-(Fluoroalkylidene)-1, 1-bisphosphonic acids are potent and selective inhibitors of the enzymatic activity of Toxoplasma gondii farnesyl pyrophosphate synthase SH Szajnman, VS Rosso, L Malayil, A Smith, SNJ Moreno, R Docampo, ... Organic & biomolecular chemistry 10 (7), 1424-1433, 2012 | 31 | 2012 |
Detection and treatment of Trypanosoma cruzi: a patent review (2011-2015) JB Rodriguez, BN Falcone, SH Szajnman Expert opinion on therapeutic patents 26 (9), 993-1015, 2016 | 29 | 2016 |
Organoselenium compounds: Chemistry and applications in organic synthesis JM Sonego, SI De Diego, SH Szajnman, C Gallo‐Rodriguez, ... Chemistry–A European Journal 29 (52), e202300030, 2023 | 28 | 2023 |
Synergistic activity between statins and bisphosphonates against acute experimental toxoplasmosis ZH Li, C Li, SH Szajnman, JB Rodriguez, SNJ Moreno Antimicrobial agents and chemotherapy 61 (8), 10.1128/aac. 02628-16, 2017 | 25 | 2017 |
2-alkylaminoethyl-1, 1-bisphosphonic acids are potent inhibitors of the enzymatic activity of Trypanosoma cruzi squalene synthase CA Rodrígues-Poveda, D González-Pacanowska, SH Szajnman, ... Antimicrobial agents and chemotherapy 56 (8), 4483-4486, 2012 | 25 | 2012 |