Epigenetics, fragmentomics, and topology of cell-free DNA in liquid biopsies YMD Lo, DSC Han, P Jiang, RWK Chiu Science 372 (6538), eaaw3616, 2021 | 362 | 2021 |
The biology of cell-free DNA fragmentation and the roles of DNASE1, DNASE1L3, and DFFB DSC Han, M Ni, RWY Chan, VWH Chan, KO Lui, RWK Chiu, YMD Lo The American Journal of Human Genetics 106 (2), 202-214, 2020 | 169 | 2020 |
The nexus of cfDNA and nuclease biology DSC Han, YMD Lo Trends in Genetics 37 (8), 758-770, 2021 | 118 | 2021 |
Plasma DNA profile associated with DNASE1L3 gene mutations: clinical observations, relationships to nuclease substrate preference, and in vivo correction RWY Chan, L Serpas, M Ni, S Volpi, LT Hiraki, LS Tam, A Rashidfarrokhi, ... The American Journal of Human Genetics 107 (5), 882-894, 2020 | 50 | 2020 |
Inhibition of interferon-beta responses in multiple sclerosis immune cells associated with high-dose statins X Feng, D Han, BK Kilaru, BS Franek, TB Niewold, AT Reder Archives of neurology 69 (10), 1303-1309, 2012 | 43 | 2012 |
Nuclease deficiencies alter plasma cell-free DNA methylation profiles DSC Han, M Ni, RWY Chan, DKL Wong, LT Hiraki, S Volpi, P Jiang, ... Genome Research 31 (11), 2008-2021, 2021 | 7 | 2021 |
High-resolution analysis for urinary DNA jagged ends T Xie, G Wang, SC Ding, WS Lee, SH Cheng, RWY Chan, Z Zhou, ... NPJ Genomic Medicine 7 (1), 14, 2022 | 6 | 2022 |
Inhibitory effect of high-dose atorvastatin on interferon-beta signalling in multiple sclerosis X Feng, D Han, B Kilaru, TB Niewold, AT Reder Multiple Sclerosis 15 (9), S78-S78, 2009 | 4 | 2009 |
Cell-free dna methylation and nuclease-mediated fragmentation YMD Lo, RWK Chiu, KC Chan, P Jiang, WY Chan, M Ni, DSC Han, TK Sin US Patent App. 17/716,395, 2022 | | 2022 |
Sitosterolaemia identified due to peri-pregnancy rebound hypercholesterolaemia SR Subramaniam, IHY Ng, DSC Han, TKC Tsui Pathology 54 (7), 962-964, 2022 | | 2022 |
Nuclease-associated end signature analysis for cell-free nucleic acids YMD Lo, RWK Chiu, KC Chan, P Jiang, WY Chan, WK Lam, DSC Han, ... US Patent App. 17/374,691, 2022 | | 2022 |
Biterminal dna fragment types in cell-free samples and uses thereof YMD Lo, RWK Chiu, DSC Han, M Ni US Patent App. 17/144,021, 2021 | | 2021 |
Cell-free dna fragmentation and nucleases YMD Lo, RWK Chiu, DSC Han, M Ni US Patent App. 17/127,194, 2021 | | 2021 |
Facial Puffiness in a 9-Year-Old Girl MT Leung, SR Subramaniam, DSC Han, LY Hung, FCK Wong Clinical Chemistry 66 (4), 627-628, 2020 | | 2020 |
Atorvastatin interference with interferon-beta signaling in human immune cells and in multiple sclerosis X Feng, D Han, AT Reder MULTIPLE SCLEROSIS JOURNAL 14, S122-S122, 2008 | | 2008 |