| Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells J Lin, Q Yang, Z Yan, J Markowitz, PT Wilder, F Carrier, DJ Weber Journal of Biological Chemistry 279 (32), 34071-34077, 2004 | 182 | 2004 |
| The Ca2+-Dependent Interaction of S100B(ββ) with a Peptide Derived from p53 RR Rustandi, AC Drohat, DM Baldisseri, PT Wilder, DJ Weber Biochemistry 37 (7), 1951-1960, 1998 | 174 | 1998 |
| Selective expansion of target cell populations M Kraus, PT Wilder, J Friberg US Patent 6,338,942, 2002 | 157 | 2002 |
| The calcium-binding protein S100B down-regulates p53 and apoptosis in malignant melanoma J Lin, Q Yang, PT Wilder, F Carrier, DJ Weber Journal of biological chemistry 285 (35), 27487-27498, 2010 | 144 | 2010 |
| S100B(ββ) inhibits the protein kinase C‐dependent phosphorylation of a peptide derived from p53 in a Ca2+‐dependent manner PT Wilder, RR Rustandi, AC Drohat, DJ Weber Protein Science 7 (3), 794-798, 1998 | 123 | 1998 |
| Recognition of the tumor suppressor protein p53 and other protein targets by the calcium-binding protein S100B PT Wilder, J Lin, CL Bair, TH Charpentier, D Yang, M Liriano, KM Varney, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1763 (11), 1284-1297, 2006 | 111 | 2006 |
| Structure of Ca2+-Bound S100A4 and Its Interaction with Peptides Derived from Nonmuscle Myosin-IIA VN Malashkevich, KM Varney, SC Garrett, PT Wilder, D Knight, ... Biochemistry 47 (18), 5111-5126, 2008 | 109 | 2008 |
| The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein–protein … X Cao, JL Yap, MK Newell-Rogers, C Peddaboina, W Jiang, ... Molecular cancer 12, 1-16, 2013 | 104 | 2013 |
| Selective expansion of target cell populations M Kraus, PT Wilder, J Friberg US Patent 5,925,567, 1999 | 104 | 1999 |
| Relaxation of the rigid backbone of an oligoamide-foldamer-based α-helix mimetic: Identification of potent Bcl-x L inhibitors JL Yap, X Cao, K Vanommeslaeghe, KY Jung, C Peddaboina, PT Wilder, ... Organic & Biomolecular Chemistry 10 (15), 2928-2933, 2012 | 89 | 2012 |
| Calcium-binding properties of wild-type and EF-hand mutants of S100B in the presence and absence of a peptide derived from the C-terminal negative regulatory domain of p53 J Markowitz, RR Rustandi, KM Varney, PT Wilder, R Udan, SL Wu, ... Biochemistry 44 (19), 7305-7314, 2005 | 77 | 2005 |
| Divalent metal ion complexes of S100B in the absence and presence of pentamidine TH Charpentier, PT Wilder, MA Liriano, KM Varney, E Pozharski, ... Journal of molecular biology 382 (1), 56-73, 2008 | 66 | 2008 |
| The effects of CapZ peptide (TRTK-12) binding to S100B–Ca2+ as examined by NMR and X-ray crystallography TH Charpentier, LE Thompson, MA Liriano, KM Varney, PT Wilder, ... Journal of molecular biology 396 (5), 1227-1243, 2010 | 61 | 2010 |
| Structure-based design of N-substituted 1-hydroxy-4-sulfamoyl-2-naphthoates as selective inhibitors of the Mcl-1 oncoprotein ME Lanning, W Yu, JL Yap, J Chauhan, L Chen, E Whiting, LS Pidugu, ... European journal of medicinal chemistry 113, 273-292, 2016 | 59 | 2016 |
| The calcium-dependent interaction between S100B and the mitochondrial AAA ATPase ATAD3A and the role of this complex in the cytoplasmic processing of ATAD3A B Gilquin, BR Cannon, A Hubstenberger, B Moulouel, E Falk, N Merle, ... Molecular and cellular biology, 2010 | 59 | 2010 |
| Amphipathic α-helix mimetics based on a 1, 2-diphenylacetylene scaffold KY Jung, K Vanommeslaeghe, ME Lanning, JL Yap, C Gordon, PT Wilder, ... Organic letters 15 (13), 3234-3237, 2013 | 55 | 2013 |
| Solution structure of S100A1 bound to the CapZ peptide (TRTK12) NT Wright, BR Cannon, PT Wilder, MT Morgan, KM Varney, DB Zimmer, ... Journal of molecular biology 386 (5), 1265-1277, 2009 | 55 | 2009 |
| Solution Structure of Zinc- and Calcium-Bound Rat S100B as Determined by Nuclear Magnetic Resonance Spectroscopy, PT Wilder, KM Varney, MB Weiss, RK Gitti, DJ Weber Biochemistry 44 (15), 5690-5702, 2005 | 52 | 2005 |
| Location of the Zn2+-Binding Site on S100B As Determined by NMR Spectroscopy and Site-Directed Mutagenesis PT Wilder, DM Baldisseri, R Udan, KM Vallely, DJ Weber Biochemistry 42 (46), 13410-13421, 2003 | 52 | 2003 |
| Structure-based design of 3-carboxy-substituted 1, 2, 3, 4-tetrahydroquinolines as inhibitors of myeloid cell leukemia-1 (Mcl-1) L Chen, PT Wilder, B Drennen, J Tran, BM Roth, K Chesko, P Shapiro, ... Organic & biomolecular chemistry 14 (24), 5505-5510, 2016 | 43 | 2016 |
