| Distinct factors control histone variant H3. 3 localization at specific genomic regions AD Goldberg, LA Banaszynski, KM Noh, PW Lewis, SJ Elsaesser, ... Cell 140 (5), 678-691, 2010 | 1390 | 2010 |
| Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases D Hockemeyer, F Soldner, C Beard, Q Gao, M Mitalipova, RC DeKelver, ... Nature biotechnology 27 (9), 851-857, 2009 | 1303 | 2009 |
| Precise genome modification in the crop species Zea mays using zinc-finger nucleases VK Shukla, Y Doyon, JC Miller, RC DeKelver, EA Moehle, SE Worden, ... Nature 459 (7245), 437-441, 2009 | 1209 | 2009 |
| Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases EA Moehle, JM Rock, YL Lee, Y Jouvenot, RC DeKelver, PD Gregory, ... Proceedings of the National Academy of Sciences 104 (9), 3055-3060, 2007 | 510 | 2007 |
| Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome RC DeKelver, VM Choi, EA Moehle, DE Paschon, D Hockemeyer, ... Genome research 20 (8), 1133-1142, 2010 | 372 | 2010 |
| In vivo genome editing of the albumin locus as a platform for protein replacement therapy R Sharma, XM Anguela, Y Doyon, T Wechsler, RC DeKelver, S Sproul, ... Blood, The Journal of the American Society of Hematology 126 (15), 1777-1784, 2015 | 354 | 2015 |
| Targeted transgene integration in plant cells using designed zinc finger nucleases CQ Cai, Y Doyon, WM Ainley, JC Miller, RC DeKelver, EA Moehle, ... Plant molecular biology 69, 699-709, 2009 | 283 | 2009 |
| Chromosomal translocations induced at specified loci in human stem cells E Brunet, D Simsek, M Tomishima, R DeKelver, VM Choi, P Gregory, ... Proceedings of the National Academy of Sciences 106 (26), 10620-10625, 2009 | 271 | 2009 |
| Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology SJ Orlando, Y Santiago, RC DeKelver, Y Freyvert, EA Boydston, ... Nucleic acids research 38 (15), e152-e152, 2010 | 266 | 2010 |
| Methods and compositions for treatment of a genetic condition A Conway, GJ Cost, R DeKelver, EJ Rebar, A Reik, F Urnov, J Wang, ... US Patent 9,873,894, 2018 | 211 | 2018 |
| Targeted integration into the PPP1R12C locus R DeKelver, PD Gregory, D Paschon, P Tam, F Urnov US Patent 8,110,379, 2012 | 183 | 2012 |
| SON controls cell-cycle progression by coordinated regulation of RNA splicing EY Ahn, RC DeKelver, MC Lo, TA Nguyen, S Matsuura, A Boyapati, ... Molecular cell 42 (2), 185-198, 2011 | 173 | 2011 |
| Linear donor constructs for targeted integration R DeKelver, PD Gregory, MC Holmes, F Urnov US Patent 9,045,763, 2015 | 127 | 2015 |
| Dose-dependent prevention of metabolic and neurologic disease in murine MPS II by ZFN-mediated in vivo genome editing K Laoharawee, RC DeKelver, KM Podetz-Pedersen, M Rohde, S Sproul, ... Molecular Therapy 26 (4), 1127-1136, 2018 | 126 | 2018 |
| SRSF2 is essential for hematopoiesis, and its myelodysplastic syndrome-related mutations dysregulate alternative pre-mRNA splicing Y Komeno, YJ Huang, J Qiu, L Lin, YJ Xu, Y Zhou, L Chen, ... Molecular and cellular biology 35 (17), 3071-3082, 2015 | 113 | 2015 |
| Transcriptional activation of Brassica napus β‐ketoacyl‐ACP synthase II with an engineered zinc finger protein transcription factor M Gupta, RC DeKelver, A Palta, C Clifford, S Gopalan, JC Miller, S Novak, ... Plant biotechnology journal 10 (7), 783-791, 2012 | 90 | 2012 |
| Non-viral delivery of zinc finger nuclease mRNA enables highly efficient in vivo genome editing of multiple therapeutic gene targets A Conway, M Mendel, K Kim, K McGovern, A Boyko, L Zhang, JC Miller, ... Molecular Therapy 27 (4), 866-877, 2019 | 85 | 2019 |
| ZFN-mediated in vivo genome editing corrects murine hurler syndrome L Ou, RC DeKelver, M Rohde, S Tom, R Radeke, SJS Martin, Y Santiago, ... Molecular Therapy 27 (1), 178-187, 2019 | 85 | 2019 |
| Engineered zinc finger proteins targeting plant genes involved in fatty acid biosynthesis R DeKelver, M Gupta, JC Miller, S Novak, JF Petolino US Patent 8,592,645, 2013 | 65 | 2013 |
| Linear donor constructs for targeted integration R DeKelver, PD Gregory, MC Holmes, F Urnov US Patent App. 12/386,059, 2009 | 58 | 2009 |
