A reference map of the human binary protein interactome K Luck, DK Kim, L Lambourne, K Spirohn, BE Begg, W Bian, R Brignall, ... Nature 580 (7803), 402-408, 2020 | 955 | 2020 |
Widespread macromolecular interaction perturbations in human genetic disorders N Sahni, S Yi, M Taipale, JIF Bass, J Coulombe-Huntington, F Yang, ... Cell 161 (3), 647-660, 2015 | 570 | 2015 |
MaveDB: an open-source platform to distribute and interpret data from multiplexed assays of variant effect D Esposito, J Weile, J Shendure, LM Starita, AT Papenfuss, FP Roth, ... Genome biology 20, 1-11, 2019 | 179 | 2019 |
A framework for exhaustively mapping functional missense variants J Weile, S Sun, AG Cote, J Knapp, M Verby, JC Mellor, Y Wu, C Pons, ... Molecular systems biology 13 (12), 957, 2017 | 179 | 2017 |
Multiplexed assays of variant effects contribute to a growing genotype–phenotype atlas J Weile, FP Roth Human genetics 137 (9), 665-678, 2018 | 127 | 2018 |
Pooled‐matrix protein interaction screens using Barcode Fusion Genetics N Yachie, E Petsalaki, JC Mellor, J Weile, Y Jacob, M Verby, SB Ozturk, ... Molecular systems biology 12 (4), 863, 2016 | 123 | 2016 |
Improved pathogenicity prediction for rare human missense variants Y Wu, H Liu, R Li, S Sun, J Weile, FP Roth The American Journal of Human Genetics 108 (10), 1891-1906, 2021 | 88 | 2021 |
Integrative pathway dissection of molecular mechanisms of moxLDL-induced vascular smooth muscle phenotype transformation GS Karagiannis, J Weile, GD Bader, J Minta BMC cardiovascular disorders 13, 1-19, 2013 | 73 | 2013 |
KeyPathwayMiner: detecting case-specific biological pathways using expression data N Alcaraz, H Kücük, J Weile, A Wipat, J Baumbach Internet Mathematics 7 (4), 299-313, 2011 | 58 | 2011 |
A proactive genotype-to-patient-phenotype map for cystathionine beta-synthase S Sun, J Weile, M Verby, Y Wu, Y Wang, AG Cote, I Fotiadou, ... Genome medicine 12, 1-18, 2020 | 54 | 2020 |
An integrated dataset for in silico drug discovery SJ Cockell, J Weile, P Lord, C Wipat, D Andriychenko, M Pocock, ... Journal of integrative bioinformatics 7 (3), 15-27, 2010 | 49 | 2010 |
Systematic analysis of bypass suppression of essential genes J Van Leeuwen, C Pons, G Tan, JZ Wang, J Hou, J Weile, M Gebbia, ... Molecular systems biology 16 (9), e9828, 2020 | 43 | 2020 |
Shifting landscapes of human MTHFR missense-variant effects J Weile, N Kishore, S Sun, R Maaieh, M Verby, R Li, I Fotiadou, ... The American Journal of Human Genetics 108 (7), 1283-1300, 2021 | 41 | 2021 |
Mapping DNA damage‐dependent genetic interactions in yeast via party mating and barcode fusion genetics JJ Díaz‐Mejía, A Celaj, JC Mellor, A Coté, A Balint, B Ho, P Bansal, ... Molecular Systems Biology 14 (5), e7985, 2018 | 30 | 2018 |
A comprehensive map of human glucokinase variant activity S Gersing, M Cagiada, M Gebbia, AP Gjesing, AG Coté, G Seesankar, ... Genome Biology 24 (1), 97, 2023 | 27 | 2023 |
MaveRegistry: a collaboration platform for multiplexed assays of variant effect D Kuang, J Weile, N Kishore, M Nguyen, AF Rubin, S Fields, DM Fowler, ... Bioinformatics 37 (19), 3382-3383, 2021 | 21 | 2021 |
A web application and service for imputing and visualizing missense variant effect maps Y Wu, J Weile, AG Cote, S Sun, J Knapp, M Verby, FP Roth Bioinformatics 35 (17), 3191-3193, 2019 | 18 | 2019 |
Bayesian integration of networks without gold standards J Weile, K James, J Hallinan, SJ Cockell, P Lord, A Wipat, D Wilkinson Bioinformatics 28 (11), 1495-1500, 2012 | 17 | 2012 |
Assessing predictions of fitness effects of missense mutations in SUMO‐conjugating enzyme UBE2I J Zhang, LN Kinch, Q Cong, J Weile, S Sun, AG Cote, FP Roth, NV Grishin Human mutation 38 (9), 1051-1063, 2017 | 16 | 2017 |
CoryneCenter–An online resource for the integrated analysis of corynebacterial genome and transcriptome data H Neuweger, J Baumbach, S Albaum, T Bekel, M Dondrup, AT Hüser, ... BMC systems biology 1, 1-12, 2007 | 15 | 2007 |