Eradication of T-ALL cells by CD7-targeted universal CAR-T cells and initial test of Ruxolitinib-based CRS management S Li, X Wang, Z Yuan, L Liu, L Luo, Y Li, K Wu, J Liu, C Yang, Z Li, ... Clinical Cancer Research 27 (5), 1242-1246, 2021 | 81 | 2021 |
Development of A Chimeric Antigen Receptor Targeting C-Type Lectin-Like Molecule-1 for Human Acute Myeloid Leukemia E Laborda, M Mazagova, S Shao, X Wang, H Quirino, AK Woods, ... International journal of molecular sciences 18 (11), 2259, 2017 | 74 | 2017 |
Lipid and protein co-regulation of PI3K effectors Akt and Itk in lymphocytes X Wang, LB Hills, YH Huang Frontiers in immunology 6, 117, 2015 | 44 | 2015 |
Mst1 kinase regulates the actin-bundling protein L-plastin to promote T cell migration X Xu, X Wang, EM Todd, ER Jaeger, JL Vella, OL Mooren, Y Feng, J Hu, ... The Journal of Immunology 197 (5), 1683-1691, 2016 | 34 | 2016 |
A novel BCMA-specific, centyrin-based CAR-T product for the treatment of multiple myeloma DL Hermanson, BE Barnett, S Rengarajan, R Codde, X Wang, Y Tan, ... Blood 128 (22), 2127-2127, 2016 | 29 | 2016 |
Abstract CT052: Clinical safety and efficacy study of TruUCAR™ GC027: The first-in-human, universal CAR-T therapy for adult relapsed/refractory T-cell acute lymphoblastic … X Wang, S Li, L Gao, Z Yuan, K Wu, L Liu, L Luo, Y Liu, C Zhang, J Liu, ... Cancer Research 80 (16 Supplement), CT052-CT052, 2020 | 28 | 2020 |
PiggyBac™-Produced CAR-T Cells Exhibit Stem-Cell Memory Phenotype BE Barnett, DL Hermanson, JB Smith, X Wang, Y Tan, CE Martin, ... Target 929, K562, 2016 | 24 | 2016 |
Calmodulin and PI (3, 4, 5) P3 cooperatively bind to the Itk pleckstrin homology domain to promote efficient calcium signaling and IL-17A production X Wang, SE Boyken, J Hu, X Xu, RP Rimer, MA Shea, AS Shaw, ... Sci. Signal. 7 (337), ra74-ra74, 2014 | 23 | 2014 |
Mst1 directs Myosin IIa partitioning of low and higher affinity integrins during T cell migration X Xu, ER Jaeger, X Wang, E Lagler-Ferrez, S Batalov, NL Mathis, ... PloS one 9 (8), e105561, 2014 | 21 | 2014 |
Rodent herpesvirus Peru encodes a secreted chemokine decoy receptor OY Lubman, M Cella, X Wang, K Monte, DJ Lenschow, YH Huang, ... Journal of virology 88 (1), 538-546, 2014 | 20 | 2014 |
Safety and efficacy results of GC027: The first-in-human, universal CAR-T cell therapy for adult relapsed/refractory T-cell acute lymphoblastic leukemia (r/r T-ALL). X Wang, S Li, L Gao, Z Yuan, K Wu, L Liu, L Luo, Y Liu, C Zhang, J Liu, ... Journal of Clinical Oncology 38 (15_suppl), 3013-3013, 2020 | 11 | 2020 |
An accurate quantitative method for screening effective siRNA probes targeting a Hepatitis B virus transcript in single living cells W Tong, Y Zhou, X Wang, F Yang, KL Wu, J Wu, Y Zhang Biochemical and biophysical research communications 367 (4), 866-873, 2008 | 10 | 2008 |
B-Cell Maturation Antigen (BCMA)-Specific, CentyrinTM-Based, PiggyBacTM-Transposed CAR-T Memory Stem Cells Are Effective Against p53-/-and Patient-Derived Multiple Myeloma Tumors R Mathur, BE Barnett, D Hermanson, J He, Z Zhang, S Rengarajan, ... Blood 130 (Suppl 1), 3068-3068, 2017 | 8 | 2017 |
Abstract LB147: Updates on clinical safety and efficacy result of GC027, the first-in-human,“Off-the-Shelf” CD7 CAR-T stand-alone therapy for adult patients with relapsed … S Li, L Gao, Z Yuan, K Wu, L Liu, L Luo, Y Liu, C Zhang, Y Li, D Wang, Z Li, ... Cancer Research 81 (13 Supplement), LB147-LB147, 2021 | 6 | 2021 |
Production of Universal Anti-Bcma CAR-T Cells with Reduced Alloreactivity, but Potent Effector Function for the Treatment of Multiple Myeloma X Wang, BE Barnett, C Martin, D Hermanson, X Li, J Smith, J Wu, ... Blood 130 (Suppl 1), 503-503, 2017 | 5 | 2017 |
Development of novel non-immunoglobulin centyrin-based cars (CARTyrins) targeting human BCMA BE Barnett, X Wang, DL Hermanson, Y Tan, EM Osertag, DJ Shedlock Blood 128 (22), 4557-4557, 2016 | 5 | 2016 |
PiggyBac-manufactured anti-BCMA Centyrin-based CAR-T therapeutic exhibits improved potency and durability D Hermanson, BE Barnett, S Rengarajan, R Codde, CE Martin, X Wang, ... Cancer Research 77 (13 Supplement), 3759-3759, 2017 | 4 | 2017 |
Preclinical Results of an Allogeneic, Universal CD19/CD7-Targeting CAR-T Cell Therapy (GC502) for B Cell Malignancies J Ge, C Yang, J Sun, J Chen, S Qiu, W Yin, L Shen, M Sersch, W Cao, ... Blood 138, 1722, 2021 | 3 | 2021 |
High Fidelity Genome Editing Using NextGEN™ CRISPR (Clo51-dCas9) System for the Production of Allogeneic CAR-T Cells X Wang, X Li, B Barnett, C Martin, D Hermanson, J Smith, S Rengarajan, ... Journal of Clinical Oncology 35, 2017 | 2 | 2017 |
The Application of ‘Drug-Reversible’CAR-T Cells Directed Against Recipient Hematopoietic Cells As a Selective Conditioning Strategy for Stem Cell Transplantation N Timberlake, M Richter, X Wang, N Cam, Y Tan, EM Ostertag, ... Blood 130 (Suppl 1), 1893-1893, 2017 | 1 | 2017 |