| Isatin-pyrazole benzenesulfonamide hybrids potently inhibit tumor-associated carbonic anhydrase isoforms IX and XII HS Ibrahim, SM Abou-Seri, M Tanc, MM Elaasser, HA Abdel-Aziz, ... European journal of medicinal chemistry 103, 583-593, 2015 | 117 | 2015 |
| Improvement of antibacterial activity of some sulfa drugs through linkage to certain phthalazin-1 (2H)-one scaffolds HS Ibrahim, WM Eldehna, HA Abdel-Aziz, MM Elaasser, MM Abdel-Aziz European journal of medicinal chemistry 85, 480-486, 2014 | 91 | 2014 |
| 3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico … MF Abo-Ashour, WM Eldehna, A Nocentini, A Bonardi, S Bua, HS Ibrahim, ... European Journal of Medicinal Chemistry 184, 111768, 2019 | 74 | 2019 |
| Novel [(3-indolylmethylene)hydrazono]indolin-2-ones as apoptotic anti-proliferative agents: design, synthesis and in vitro biological evaluation WM Eldehna, MF Abo-Ashour, HS Ibrahim, GH Al-Ansary, HA Ghabbour, ... Journal of enzyme inhibition and medicinal chemistry 33 (1), 686-700, 2018 | 73 | 2018 |
| Pyridine-ureas as potential anticancer agents: synthesis and in vitro biological evaluation M El-Naggar, H Almahli, HS Ibrahim, WM Eldehna, HA Abdel-Aziz Molecules 23 (6), 1459, 2018 | 72 | 2018 |
| Bis-isatin hydrazones with novel linkers: Synthesis and biological evaluation as cytotoxic agents HS Ibrahim, SM Abou-Seri, NSM Ismail, MM Elaasser, MH Aly, ... European Journal of Medicinal Chemistry 108, 415-422, 2016 | 67 | 2016 |
| Dual-tail arylsulfone-based benzenesulfonamides differently match the hydrophobic and hydrophilic halves of human carbonic anhydrases active sites: Selective inhibitors for the … HS Ibrahim, HA Allam, WR Mahmoud, A Bonardi, A Nocentini, P Gratteri, ... European Journal of Medicinal Chemistry 152, 1-9, 2018 | 66 | 2018 |
| One-pot three-component synthesis of novel spirooxindoles with potential cytotoxic activity against triple-negative breast cancer MDA-MB-231 cells WM Eldehna, DH El-Naggar, AR Hamed, HS Ibrahim, HA Ghabbour, ... Journal of enzyme inhibition and medicinal chemistry 33 (1), 309-318, 2018 | 65 | 2018 |
| Design, synthesis and in vitro antitumor activity of novel N-substituted-4-phenyl/benzylphthalazin-1-ones WM Eldehna, HS Ibrahim, HA Abdel-Aziz, NN Farrag, MM Youssef European Journal of Medicinal Chemistry 89, 549-560, 2015 | 65 | 2015 |
| Indoline ureas as potential anti-hepatocellular carcinoma agents targeting VEGFR-2: Synthesis, in vitro biological evaluation and molecular docking WM Eldehna, M Fares, HS Ibrahim, MH Aly, S Zada, MM Ali, ... European journal of medicinal chemistry 100, 89-97, 2015 | 62 | 2015 |
| Novel hydrazido benzenesulfonamides-isatin conjugates: Synthesis, carbonic anhydrase inhibitory activity and molecular modeling studies MF Abo-Ashour, WM Eldehna, A Nocentini, HS Ibrahim, S Bua, ... European Journal of Medicinal Chemistry 157, 28-36, 2018 | 55 | 2018 |
| Novel synthesized SLC-0111 thiazole and thiadiazole analogues: Determination of their carbonic anhydrase inhibitory activity and molecular modeling studies MF Abo-Ashour, WM Eldehna, A Nocentini, HS Ibrahim, S Bua, ... Bioorganic Chemistry 87, 794-802, 2019 | 54 | 2019 |
| Analogue-based design, synthesis and biological evaluation of 3-substituted-(methylenehydrazono) indolin-2-ones as anticancer agents HE Dweedar, H Mahrous, HS Ibrahim, HA Abdel-Aziz European Journal of Medicinal Chemistry 78, 275-280, 2014 | 50 | 2014 |
| Novel 3-substituted coumarins as selective human carbonic anhydrase IX and XII inhibitors: Synthesis, biological and molecular dynamics analysis MA Abdelrahman, HS Ibrahim, A Nocentini, WM Eldehna, A Bonardi, ... European Journal of Medicinal Chemistry 209, 112897, 2021 | 48 | 2021 |
| Synthesis and cytotoxic activity of biphenylurea derivatives containing indolin-2-one moieties WM Eldehna, M Fares, HS Ibrahim, MA Alsherbiny, MH Aly, HA Ghabbour, ... Molecules 21 (6), 762, 2016 | 42 | 2016 |
| Synthesis of diarylpyrazoles containing a phenylsulphone or carbonitrile moiety and their chalcones as possible anti-inflammatory agents E Nassar, HA Abdel-Aziz, HS Ibrahim, AM Mansour Scientia pharmaceutica 79 (3), 507-524, 2011 | 40 | 2011 |
| Synthesis, molecular docking and biological characterization of pyrazine linked 2-aminobenzamides as new class I selective histone deacetylase (HDAC) inhibitors with anti … HS Ibrahim, M Abdelsalam, Y Zeyn, M Zessin, AHM Mustafa, MA Fischer, ... International Journal of Molecular Sciences 23 (1), 369, 2021 | 31 | 2021 |
| 3-Hydrazinoindolin-2-one derivatives: chemical classification and investigation of their targets as anticancer agents HS Ibrahim, SM Abou-Seri, HA Abdel-Aziz European journal of medicinal chemistry 122, 366-381, 2016 | 31 | 2016 |
| Importance of glutamine 189 flexibility in SARS-CoV-2 main protease: Lesson learned from in silico virtual screening of ChEMBL database and molecular dynamics MA Said, A Albohy, MA Abdelrahman, HS Ibrahim European Journal of Pharmaceutical Sciences 160, 105744, 2021 | 26 | 2021 |
| Synthesis and biological evaluation of some novel thiobenzimidazole derivatives as anti-renal cancer agents through inhibition of c-MET kinase HS Ibrahim, ME Albakri, WR Mahmoud, HA Allam, AM Reda, ... Bioorganic chemistry 85, 337-348, 2019 | 26 | 2019 |
Prof. Hatem A. Abdel-AzizDepartment of Applied Organic Chemistry, National Research Centre, Cairo, Egypt在 nrc.sci.eg 的电子邮件经过验证
