Genetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae A Piazza, JB Boulé, J Lopes, K Mingo, E Largy, MP Teulade-Fichou, ... Nucleic Acids Research 38 (13), 4337-4348, 2010 | 201 | 2010 |
Role of alkali metal ions in G-quadruplex nucleic acid structure and stability E Largy, JL Mergny, V Gabelica The alkali metal ions: Their role for life, 203-258, 2016 | 174* | 2016 |
Development of a high-throughput G4-FID assay for screening and evaluation of small molecules binding quadruplex nucleic acid structures E Largy, F Hamon, MP Teulade-Fichou Analytical and Bioanalytical Chemistry, 1-9, 2011 | 140 | 2011 |
Quadruplex turncoats: cation-dependent folding and stability of quadruplex-DNA double switches E Largy, A Marchand, S Amrane, V Gabelica, JL Mergny Journal of the American Chemical Society 138 (8), 2780-2792, 2016 | 132 | 2016 |
Visualizing the quadruplex: from fluorescent ligands to light-up probes E Largy, A Granzhan, F Hamon, D Verga, MP Teulade-Fichou Quadruplex Nucleic Acids, 111-177, 2012 | 128 | 2012 |
Fluorescence intercalator displacement assay for screening G4 ligands towards a variety of G-quadruplex structures. PL Tran, E Largy, F Hamon, MP Teulade-Fichou, JL Mergny Biochimie, 2011 | 122 | 2011 |
An Acyclic Oligoheteroaryle That Discriminates Strongly between Diverse G‐Quadruplex Topologies F Hamon, E Largy, A Guédin‐Beaurepaire, M Rouchon‐Dagois, A Sidibe, ... Angewandte Chemie 123 (37), 8904-8908, 2011 | 119* | 2011 |
Tridentate N‐Donor Palladium (II) Complexes as Efficient Coordinating Quadruplex DNA Binders E Largy, F Hamon, F Rosu, V Gabelica, E De Pauw, A Guédin, JL Mergny, ... Chemistry–A European Journal 17 (47), 13274-13283, 2011 | 86 | 2011 |
Shape matters: size-exclusion HPLC for the study of nucleic acid structural polymorphism E Largy, JL Mergny Nucleic acids research 42 (19), e149-e149, 2014 | 85 | 2014 |
Orthogonal liquid chromatography–mass spectrometry methods for the comprehensive characterization of therapeutic glycoproteins, from released glycans to intact protein level E Largy, F Cantais, G Van Vyncht, A Beck, A Delobel Journal of Chromatography A 1498, 128-146, 2017 | 83 | 2017 |
Asymmetric distyrylpyridinium dyes as red‐emitting fluorescent probes for quadruplex DNA X Xie, B Choi, E Largy, R Guillot, A Granzhan, MP Teulade‐Fichou Chemistry–A European Journal 19 (4), 1214-1226, 2013 | 79 | 2013 |
IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates L Belarif, C Mary, L Jacquemont, HL Mai, R Danger, J Hervouet, D Minault, ... Nature communications 9 (1), 4483, 2018 | 69 | 2018 |
Mass spectrometry of nucleic acid noncovalent complexes E Largy, A Konig, A Ghosh, D Ghosh, S Benabou, F Rosu, V Gabelica Chemical Reviews 122 (8), 7720-7839, 2021 | 53 | 2021 |
Macrocyclic DNA‐Mismatch‐Binding Ligands: Structural Determinants of Selectivity A Granzhan, E Largy, N Saettel, MP Teulade‐Fichou Chemistry–A European Journal 16 (3), 878-889, 2010 | 53 | 2010 |
Efficient Suppression of Gene Expression by Targeting 5′‐UTR‐Based RNA Quadruplexes with Bisquinolinium Compounds K Halder, E Largy, M Benzler, MP Teulade‐Fichou, JS Hartig ChemBioChem 12 (11), 1663-1668, 2011 | 50 | 2011 |
Nucleic acids targeted to drugs: SELEX against a quadruplex ligand. FA Renaud, F Hamon, C Di Primo, E Largy, E Dausse, L Delaurière, ... Biochimie, 2011 | 40* | 2011 |
Cationic Pentaheteroaryls as Selective G‐Quadruplex Ligands by Solvent‐Free Microwave‐Assisted Synthesis M Petenzi, D Verga, E Largy, F Hamon, F Doria, MP Teulade‐Fichou, ... Chemistry–A European Journal 18 (45), 14487-14496, 2012 | 32 | 2012 |
DNA G-quadruplexes for native mass spectrometry in potassium: a database of validated structures in electrospray-compatible conditions A Ghosh, E Largy, V Gabelica Nucleic Acids Research 49 (4), 2333-2345, 2021 | 31 | 2021 |
Unexpected position-dependent effects of ribose G-quartets in G-quadruplexes J Zhou, S Amrane, F Rosu, GF Salgado, Y Bian, H Tateishi-Karimata, ... Journal of the American Chemical Society 139 (23), 7768-7779, 2017 | 30 | 2017 |
Locking up the AS1411 aptamer with a flanking duplex: towards an improved nucleolin-targeting A Miranda, T Santos, E Largy, C Cruz Pharmaceuticals 14 (2), 121, 2021 | 21 | 2021 |