Supersensitive kappa opioid receptors promotes ethanol withdrawal-related behaviors and reduce dopamine signaling in the nucleus accumbens JH Rose, AN Karkhanis, R Chen, D Gioia, MF Lopez, HC Becker, ... International Journal of Neuropsychopharmacology 19 (5), pyv127, 2016 | 135 | 2016 |
Adolescent social isolation as a model of heightened vulnerability to comorbid alcoholism and anxiety disorders TR Butler, AN Karkhanis, SR Jones, JL Weiner Alcoholism: Clinical and Experimental Research 40 (6), 1202-1214, 2016 | 126 | 2016 |
Early-life social isolation stress increases kappa opioid receptor responsiveness and downregulates the dopamine system AN Karkhanis, JH Rose, JL Weiner, SR Jones Neuropsychopharmacology 41 (9), 2263-2274, 2016 | 120 | 2016 |
Dynorphin/kappa opioid receptor signaling in preclinical models of alcohol, drug, and food addiction A Karkhanis, KM Holleran, SR Jones International review of neurobiology 136, 53-88, 2017 | 117 | 2017 |
Social isolation rearing increases dopamine uptake and psychostimulant potency in the striatum JT Yorgason, ES Calipari, MJ Ferris, AN Karkhanis, SC Fordahl, ... Neuropharmacology 101, 471-479, 2016 | 100 | 2016 |
Chronic intermittent ethanol exposure reduces presynaptic dopamine neurotransmission in the mouse nucleus accumbens AN Karkhanis, JH Rose, KN Huggins, JK Konstantopoulos, SR Jones Drug and alcohol dependence 150, 24-30, 2015 | 91 | 2015 |
Social isolation rearing increases nucleus accumbens dopamine and norepinephrine responses to acute ethanol in adulthood AN Karkhanis, JL Locke, BA McCool, JL Weiner, SR Jones Alcoholism: Clinical and Experimental Research 38 (11), 2770-2779, 2014 | 82 | 2014 |
Switch from excitatory to inhibitory actions of ethanol on dopamine levels after chronic exposure: Role of kappa opioid receptors AN Karkhanis, KN Huggins, JH Rose, SR Jones Neuropharmacology 110, 190-197, 2016 | 73 | 2016 |
Chronic social isolation during adolescence augments catecholamine response to acute ethanol in the basolateral amygdala AN Karkhanis, NJ Alexander, BA McCool, JL Weiner, SR Jones Synapse 69 (8), 385-395, 2015 | 53 | 2015 |
Dopaminergic cellular and circuit contributions to kappa opioid receptor mediated aversion EB Margolis, AN Karkhanis Neurochemistry International 129, 104504, 2019 | 46 | 2019 |
Chronic social isolation stress during peri-adolescence alters presynaptic dopamine terminal dynamics via augmentation in accumbal dopamine availability AN Karkhanis, AC Leach, JT Yorgason, A Uneri, S Barth, F Niere, ... ACS chemical neuroscience 10 (4), 2033-2044, 2018 | 39 | 2018 |
Dynorphin and its role in alcohol use disorder AN Karkhanis, R Al-Hasani Brain research 1735, 146742, 2020 | 34 | 2020 |
Kappa-opioid receptor-dependent changes in dopamine and anxiety-like or approach-avoidance behavior occur differentially across the nucleus accumbens shell rostro-caudal axis BE Pirino, MB Spodnick, AT Gargiulo, GR Curtis, JR Barson, ... Neuropharmacology 181, 108341, 2020 | 31 | 2020 |
Distinct effects of nalmefene on dopamine uptake rates and kappa opioid receptor activity in the nucleus accumbens following chronic intermittent ethanol exposure JH Rose, AN Karkhanis, B Steiniger-Brach, SR Jones International Journal of Molecular Sciences 17 (8), 1216, 2016 | 30 | 2016 |
Cross-species alterations in synaptic dopamine regulation after chronic alcohol exposure CA Siciliano, AN Karkhanis, KM Holleran, JR Melchior, SR Jones The neuropharmacology of alcohol, 213-238, 2018 | 28 | 2018 |
KOR control over addiction processing: an exploration of the mesolimbic dopamine pathway PM Estave, MB Spodnick, AN Karkhanis The Kappa Opioid Receptor, 351-377, 2020 | 19 | 2020 |
The individual and combined effects of phenmetrazine and mgluR2/3 agonist LY379268 on the motivation to self-administer cocaine AN Karkhanis, TJR Beveridge, BE Blough, SR Jones, MJ Ferris Drug and alcohol dependence 166, 51-60, 2016 | 19 | 2016 |
Adolescent intermittent ethanol exposure effects on kappa opioid receptor mediated dopamine transmission: sex and age of exposure matter MB Spodnick, RT Amirault, TT Towner, EI Varlinskaya, LP Spear, ... Brain Sciences 10 (8), 472, 2020 | 14 | 2020 |
Sex‐related differences in pattern of ethanol drinking under the intermittent‐access model and its impact on exploratory and anxiety‐like behavior in Long‐Evans rats BE Pirino, CR Martin, BA Carpenter, GR Curtis, CM Curran‐Alfaro, ... Alcoholism: Clinical and Experimental Research 46 (7), 1282-1293, 2022 | 13 | 2022 |
Spatial effects of shifting prisms on properties of posterior parietal cortex neurons AN Karkhanis, B Heider, FM Silva, RM Siegel The Journal of Physiology 592 (16), 3625-3646, 2014 | 5 | 2014 |