Inhibition of nonhomologous end joining to increase the specificity of CRISPR/Cas9 genome editing SV Vartak, SC Raghavan The FEBS journal 282 (22), 4289-4294, 2015 | 131 | 2015 |
Novel BCL2 inhibitor, Disarib induces apoptosis by disruption of BCL2-BAK interaction SV Vartak, D Iyer, TR Santhoshkumar, S Sharma, A Mishra, G Goldsmith, ... Biochemical pharmacology 131, 16-28, 2017 | 48 | 2017 |
Identification of a novel BCL 2‐specific inhibitor that binds predominantly to the BH 1 domain D Iyer, SV Vartak, A Mishra, G Goldsmith, S Kumar, M Srivastava, ... The FEBS journal 283 (18), 3408-3437, 2016 | 48 | 2016 |
Autocyclized and oxidized forms of SCR 7 induce cancer cell death by inhibiting nonhomologous DNA end joining in a Ligase IV dependent manner SV Vartak, HA Swarup, V Gopalakrishnan, VK Gopinatha, V Ropars, ... The FEBS journal 285 (21), 3959-3976, 2018 | 45 | 2018 |
Enhanced efficacy of pluronic copolymer micelle encapsulated SCR7 against cancer cell proliferation F John, J George, SV Vartak, M Srivastava, PA Hassan, VK Aswal, ... Macromolecular bioscience 15 (4), 521-534, 2015 | 35 | 2015 |
G-quadruplex structures contribute to differential radiosensitivity of the human genome N Kumari, SV Vartak, S Dahal, S Kumari, SS Desai, V Gopalakrishnan, ... Iscience 21, 288-307, 2019 | 29 | 2019 |
A novel inhibitor of BCL2, Disarib abrogates tumor growth while sparing platelets, by activating intrinsic pathway of apoptosis SV Vartak, M Hegde, D Iyer, S Gaikwad, V Gopalakrishnan, M Srivastava, ... Biochemical pharmacology 122, 10-22, 2016 | 28 | 2016 |
“Stripe” transcription factors provide accessibility to co-binding partners in mammalian genomes Y Zhao, SV Vartak, A Conte, X Wang, DA Garcia, E Stevens, SK Jung, ... Molecular cell 82 (18), 3398-3411. e11, 2022 | 24 | 2022 |
A benzothiazole derivative (5g) induces DNA damage and potent G2/M arrest in cancer cells M Hegde, SV Vartak, CV Kavitha, H Ananda, DS Prasanna, ... Scientific Reports 7 (1), 2533, 2017 | 24 | 2017 |
NHEJ inhibitor SCR7 and its different forms: Promising CRISPR tools for genome engineering U Ray, SV Vartak, SC Raghavan Gene 763, 144997, 2020 | 15 | 2020 |
Water-soluble version of SCR7-pyrazine inhibits DNA repair and abrogates tumor cell proliferation M Pandey, V Gopalakrishnan, HA Swarup, S Kumar, R Gudapureddy, ... Journal of Radiation and Cancer Research 10 (1), 27-43, 2019 | 12 | 2019 |
SCR7, an inhibitor of NHEJ can sensitize tumor cells to ionization radiation V Gopalakrishnan, S Sharma, U Ray, M Manjunath, D Lakshmanan, ... Molecular Carcinogenesis 60 (9), 627-643, 2021 | 11 | 2021 |
Discovery of novel approach for regioselective synthesis of thioxotriaza-spiro derivatives via oxalic acid VK Gopinatha, HA Swarup, SC Raghavan, K Mantelingu, KS Rangappa Synlett 30 (17), 2004-2009, 2019 | 11 | 2019 |
G-quadruplex structures contribute to differential radiosensitivity of the human genome, iScience, 21 N Kumari, SV Vartak, S Dahal, S Kumari, SS Desai, V Gopalakrishnan, ... | 8 | 2019 |
G4 DNA present at human telomeric DNA contributes toward reduced sensitivity to γ-radiation induced oxidative damage, but not bulky adduct formation U Ray, S Sharma, I Kapoor, S Kumari, V Gopalakrishnan, SV Vartak, ... International Journal of Radiation Biology 97 (9), 1166-1180, 2021 | 3 | 2021 |
Role of G4 DNA in differential radio-protection of the genome SV Vartak, SC Raghavan Journal of Radiation and Cancer Research 7 (1), 32, 2016 | | 2016 |
Epz015938 Inhibitor V Gopalakrishnan, S Sharma, U Ray, M Manjunath, D Lakshmanan, ... | | |
Hormones Signaling U Ray, SV Vartak, SC Raghavan | | |