| Strength of selection pressure is an important parameter contributing to the complexity of antibiotic resistance evolution T Oz, A Guvenek, S Yildiz, E Karaboga, YT Tamer, N Mumcuyan, VB Ozan, ... Molecular biology and evolution 31 (9), 2387-2401, 2014 | 276 | 2014 |
| Sequence-specific targeting of bacterial resistance genes increases antibiotic efficacy DH Ayhan, YT Tamer, M Akbar, SM Bailey, M Wong, SM Daly, ... PLoS biology 14 (9), e1002552, 2016 | 92 | 2016 |
| High-Order Epistasis in Catalytic Power of Dihydrofolate Reductase Gives Rise to a Rugged Fitness Landscape in the Presence of Trimethoprim Selection YT Tamer, IK Gaszek, H Abdizadeh, T Batur, K Reynolds, AR Atilgan, ... Molecular Biology and Evolution 36 (7), 1533–1550, 2019 | 64 | 2019 |
| A trimethoprim derivative impedes antibiotic resistance evolution MS Manna, YT Tamer, I Gaszek, N Poulides, A Ahmed, X Wang, ... Nature communications 12 (1), 2949, 2021 | 51 | 2021 |
| Rapid ultrasensitive detection platform for antimicrobial susceptibility testing MF Cansizoglu, YT Tamer, M Farid, AY Koh, E Toprak PLoS biology 17 (5), e3000291, 2019 | 33 | 2019 |
| Increased substrate affinity in the Escherichia coli L28R dihydrofolate reductase mutant causes trimethoprim resistance H Abdizadeh, YT Tamer, O Acar, E Toprak, AR Atilgan, C Atilgan Physical Chemistry Chemical Physics 19 (18), 11416-11428, 2017 | 29 | 2017 |
| The antibiotic efflux protein TolC is a highly evolvable target under colicin E1 or TLS phage selection YT Tamer, I Gaszek, M Rodrigues, FS Coskun, M Farid, AY Koh, W Russ, ... Molecular biology and evolution 38 (10), 4493-4504, 2021 | 19 | 2021 |
| Non-antibiotic small-molecule regulation of DHFR-based destabilizing domains in vivo H Peng, VQ Chau, W Phetsang, RM Sebastian, MRL Stone, S Datta, ... Molecular Therapy-Methods & Clinical Development 15, 27-39, 2019 | 16 | 2019 |
| On the race to starvation: how do bacteria survive high doses of antibiotics? YT Tamer, E Toprak Molecular cell 68 (6), 1019-1021, 2017 | 8 | 2017 |
| Know Thy Patient: A Novel Approach and Method for Patient Segmentation and Clustering Using Machine Learning to Develop Holistic, Patient-Centered Programs and Treatment Plans YT Tamer, A Karam, T Roderick, S Miff NEJM Catalyst Innovations in Care Delivery 3 (4), 2022 | 4 | 2022 |
| Fourier transform infrared spectroscopy as a novel approach for analyzing the biochemical effects of anionic surfactants on a surfactant-degrading arcobacter butzleri strain OF Sarioglu, YT Tamer, AD Ozkan, HI Atabay, C Molva, T Tekinay Applied Spectroscopy 67 (4), 470-475, 2013 | 4 | 2013 |
| A synthetic knob for modulating antibiotic resistance DH Ayhan, YT Tamer, M Akbar, DE Greenberg, E Toprak Biophysical Journal 110 (3), 477a, 2016 | 3 | 2016 |
| Patient Cluster Identification System and Method Y Tamer, A Karam, S Miff, BA Moran, J Longo US Patent App. 18/098,099, 2023 | 1 | 2023 |
| Dynamical shifts in hydrogen bond occupancies identify mechanisms responsible for resistance conferring mutations E Cetin, YT Tamer, E Toprak, AR Atilgan, C Atilgan Biophysical Journal 121 (3), 455a-456a, 2022 | 1 | 2022 |
| A rapid and highly sensitive optical platform for pathogen detection and antimicrobial sensitivity testing (Conference Presentation) MF Cansizoglu, YT Tamer, M Farid, AY Koh, E Toprak Optical Fibers and Sensors for Medical Diagnostics and Treatment …, 2020 | | 2020 |
| Exploiting Evolutionary Tradeoffs to Fight Evolution of Antibiotic Resistance YT Tamer | | 2019 |
| Molecular insights for resistance conferring mutations in competitive inhibition H Abdizadeh, YT Tamer, E Toprak, AR Atilgan, C Atilgan European biophysics journal with biophysics letters 46, S149-S149, 2017 | | 2017 |
| Quantifying the Molecular Constraints Driving the Trimethoprim Resistance in Escherichia Coli YT Tamer, E Toprak Biophysical Journal 110 (3), 397a, 2016 | | 2016 |
| Computational assessment of trimethoprim resistance in dihydrofolate reductase H Abdizadeh, O Acar, TF Guclu, YT Tamer, TA Batur, E Toprak, AR Atilgan, ... Biophysical Journal 110 (3), 47a-48a, 2016 | | 2016 |
| Studying genetic and enzymatic constraints driving evolution of antibiotic resistance YT Tamer | | 2014 |
Erdal Toprak, PhDUniversity of Texas Southwestern Medical Center, Green Center for Systems Biology在 utsouthwestern.edu 的电子邮件经过验证
