A proteomic atlas of senescence-associated secretomes for aging biomarker development N Basisty, A Kale, OH Jeon, C Kuehnemann, T Payne, C Rao, A Holtz, ... PLoS biology 18 (1), e3000599, 2020 | 864 | 2020 |
Altered proteome turnover and remodeling by short‐term caloric restriction or rapamycin rejuvenate the aging heart DF Dai, PP Karunadharma, YA Chiao, N Basisty, D Crispin, EJ Hsieh, ... Aging cell 13 (3), 529-539, 2014 | 332 | 2014 |
Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages AJ Covarrubias, A Kale, R Perrone, JA Lopez-Dominguez, AO Pisco, ... Nature metabolism 2 (11), 1265-1283, 2020 | 258 | 2020 |
Post-translational protein acetylation: an elegant mechanism for bacteria to dynamically regulate metabolic functions DG Christensen, X Xie, N Basisty, J Byrnes, S McSweeney, B Schilling, ... Frontiers in Microbiology 10, 1604, 2019 | 163 | 2019 |
Global proteomics and pathway analysis of pressure-overload–induced heart failure and its attenuation by mitochondrial-targeted peptides DF Dai, EJ Hsieh, T Chen, LG Menendez, NB Basisty, L Tsai, RP Beyer, ... Circulation: Heart Failure 6 (5), 1067-1076, 2013 | 158 | 2013 |
Mitochondrial dysfunction in cardiac aging A Tocchi, EK Quarles, N Basisty, L Gitari, PS Rabinovitch Biochimica et Biophysica Acta (BBA)-Bioenergetics 1847 (11), 1424-1433, 2015 | 143 | 2015 |
Algorithmic assessment of cellular senescence in experimental and clinical specimens J Kohli, B Wang, SM Brandenburg, N Basisty, K Evangelou, ... Nature protocols 16 (5), 2471-2498, 2021 | 120 | 2021 |
SILAC analysis reveals increased secretion of hemostasis-related factors by senescent cells CD Wiley, S Liu, C Limbad, AM Zawadzka, J Beck, M Demaria, R Artwood, ... Cell reports 28 (13), 3329-3337. e5, 2019 | 120 | 2019 |
Rapamycin transiently induces mitochondrial remodeling to reprogram energy metabolism in old hearts YA Chiao, SC Kolwicz, N Basisty, A Gagnidze, J Zhang, H Gu, D Djukovic, ... Aging (Albany NY) 8 (2), 314, 2016 | 119 | 2016 |
Protein turnover in aging and longevity N Basisty, JG Meyer, B Schilling Proteomics 18 (5-6), 1700108, 2018 | 112 | 2018 |
Mechanisms, detection, and relevance of protein acetylation in prokaryotes DG Christensen, JT Baumgartner, X Xie, KM Jew, N Basisty, B Schilling, ... MBio 10 (2), 10.1128/mbio. 02708-18, 2019 | 111 | 2019 |
Plasma proteomic biomarker signature of age predicts health and life span T Tanaka, N Basisty, G Fantoni, J Candia, AZ Moore, A Biancotto, ... Elife 9, e61073, 2020 | 104 | 2020 |
Subacute calorie restriction and rapamycin discordantly alter mouse liver proteome homeostasis and reverse aging effects PP Karunadharma, N Basisty, DF Dai, YA Chiao, EK Quarles, EJ Hsieh, ... Aging cell 14 (4), 547-557, 2015 | 102 | 2015 |
Sirtuin 5 regulates proximal tubule fatty acid oxidation to protect against AKI T Chiba, KD Peasley, KR Cargill, KV Maringer, SS Bharathi, E Mukherjee, ... Journal of the American Society of Nephrology 30 (12), 2384-2398, 2019 | 98 | 2019 |
Composition and acidification of the culture medium influences chronological aging similarly in vineyard and laboratory yeast CJ Murakami, V Wall, N Basisty, M Kaeberlein PloS one 6 (9), e24530, 2011 | 90 | 2011 |
Late-life restoration of mitochondrial function reverses cardiac dysfunction in old mice YA Chiao, H Zhang, M Sweetwyne, J Whitson, YS Ting, N Basisty, ... Elife 9, e55513, 2020 | 88 | 2020 |
Proteomics in aging research: A roadmap to clinical, translational research R Moaddel, C Ubaida‐Mohien, T Tanaka, A Lyashkov, N Basisty, ... Aging Cell 20 (4), e13325, 2021 | 82 | 2021 |
Stable nuclear expression of ATP8 and ATP6 genes rescues a mtDNA Complex V null mutant A Boominathan, S Vanhoozer, N Basisty, K Powers, AL Crampton, ... Nucleic acids research 44 (19), 9342-9357, 2016 | 81 | 2016 |
Rapamycin persistently improves cardiac function in aged, male and female mice, even following cessation of treatment E Quarles, N Basisty, YA Chiao, G Merrihew, H Gu, MT Sweetwyne, ... Aging Cell 19 (2), e13086, 2020 | 79 | 2020 |
Age modifies respiratory complex I and protein homeostasis in a muscle type‐specific manner SE Kruse, PP Karunadharma, N Basisty, R Johnson, RP Beyer, ... Aging Cell 15 (1), 89-99, 2016 | 75 | 2016 |