PAMPA—a drug absorption in vitro model: 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones M Bermejo, A Avdeef, A Ruiz, R Nalda, JA Ruell, O Tsinman, I González, ... European Journal of Pharmaceutical Sciences 21 (4), 429-441, 2004 | 246 | 2004 |
Usefulness of Caco-2/HT29-MTX and Caco-2/HT29-MTX/Raji B coculture models to predict intestinal and colonic permeability compared to Caco-2 monoculture I Lozoya-Agullo, F Araujo, I Gonzalez-Alvarez, M Merino-Sanjuan, ... Molecular pharmaceutics 14 (4), 1264-1270, 2017 | 162 | 2017 |
Biowaiver monographs for immediate release solid oral dosage forms: Aciclovir J Arnal, I Gonzalez‐Alvarez, M Bermejo, GL Amidon, HE Junginger, ... Journal of pharmaceutical sciences 97 (12), 5061-5073, 2008 | 129 | 2008 |
Giardiasis: characteristics, pathogenesis and new insights about treatment V Vivancos, I González-Alvarez, M Bermejo, M Gonzalez-Alvarez Current topics in medicinal chemistry 18 (15), 1287-1303, 2018 | 100 | 2018 |
Cyclometalated iminophosphorane gold (III) and platinum (II) complexes. A highly permeable cationic platinum (II) compound with promising anticancer properties M Frik, J Fernández-Gallardo, O Gonzalo, V Mangas-Sanjuan, ... Journal of medicinal chemistry 58 (15), 5825-5841, 2015 | 99 | 2015 |
A topological substructural approach for the prediction of P-glycoprotein substrates MA Cabrera, I González, C Fernández, C Navarro, M Bermejo Journal of Pharmaceutical Sciences 95 (3), 589-606, 2006 | 83 | 2006 |
In-situ intestinal rat perfusions for human Fabs prediction and BCS permeability class determination: Investigation of the single-pass vs. the Doluisio experimental approaches I Lozoya-Agullo, M Zur, O Wolk, A Beig, I González-Álvarez, ... International journal of pharmaceutics 480 (1-2), 1-7, 2015 | 82 | 2015 |
Provisional Classification and in Silico Study of Biopharmaceutical System Based on Caco-2 Cell Permeability and Dose Number H Pham-The, T Garrigues, M Bermejo, I González-Álvarez, ... Molecular Pharmaceutics 10 (6), 2445-2461, 2013 | 75 | 2013 |
In situ perfusion model in rat colon for drug absorption studies: Comparison with small intestine and Caco-2 cell model I Lozoya-Agullo, I González-Álvarez, M González-Álvarez, ... Journal of pharmaceutical sciences 104 (9), 3136-3145, 2015 | 72 | 2015 |
In silico prediction of Caco‐2 cell permeability by a classification QSAR approach H Pham The, I González‐Álvarez, M Bermejo, V Mangas Sanjuan, ... Molecular informatics 30 (4), 376-385, 2011 | 70 | 2011 |
Covalently crosslinked organophosphorous derivatives-chitosan hydrogel as a drug delivery system for oral administration of camptothecin M Martínez-Martínez, G Rodríguez-Berna, M Bermejo, I Gonzalez-Alvarez, ... European Journal of Pharmaceutics and Biopharmaceutics 136, 174-183, 2019 | 59 | 2019 |
Improvement of effect of water-in-oil microemulsion as an oral delivery system for fexofenadine: in vitro and in vivo studies E Gundogdu, IG Alvarez, E Karasulu International journal of nanomedicine, 1631-1640, 2011 | 59 | 2011 |
Segmental-dependent permeability throughout the small intestine following oral drug administration: Single-pass vs. Doluisio approach to in-situ rat perfusion I Lozoya-Agullo, M Zur, A Beig, N Fine, Y Cohen, M González-Álvarez, ... International journal of pharmaceutics 515 (1-2), 201-208, 2016 | 58 | 2016 |
Evaluation and optimized selection of supersaturating drug delivery systems of posaconazole (BCS class 2b) in the gastrointestinal simulator (GIS): An in vitro-in silico-in … B Hens, M Bermejo, Y Tsume, I Gonzalez-Alvarez, H Ruan, K Matsui, ... European Journal of Pharmaceutical Sciences 115, 258-269, 2018 | 54 | 2018 |
Ionic hydrogel based on chitosan cross-linked with 6-phosphogluconic trisodium salt as a drug delivery system M Martínez-Martínez, G Rodríguez-Berna, I Gonzalez-Alvarez, ... Biomacromolecules 19 (4), 1294-1304, 2018 | 53 | 2018 |
New insights of oral colonic drug delivery systems for inflammatory bowel disease therapy AH Teruel, I Gonzalez-Alvarez, M Bermejo, V Merino, MD Marcos, ... International journal of molecular sciences 21 (18), 6502, 2020 | 50 | 2020 |
Kinetic modelling of passive transport and active efflux of a fluoroquinolone across Caco-2 cells using a compartmental approach in NONMEM I González-Alvarez, C Fernandez-Teruel, TM Garrigues, VG Casabo, ... Xenobiotica 35 (12), 1067-1088, 2005 | 50 | 2005 |
Evaluation of the intestinal permeability of rosemary (Rosmarinus officinalis L.) extract polyphenols and terpenoids in Caco-2 cell monolayers A Perez-Sanchez, I Borras-Linares, E Barrajon-Catalan, D Arraez-Roman, ... PLoS One 12 (2), e0172063, 2017 | 45 | 2017 |
Drug penetration across the blood–brain barrier: an overview V Mangas-Sanjuan, M González-Alvarez, I Gonzalez-Alvarez, M Bermejo Therapeutic delivery 1 (4), 535-562, 2010 | 44 | 2010 |
Phenolic compounds in rosemary as potential source of bioactive compounds against colorectal cancer: In situ absorption and metabolism study Á Fernández-Ochoa, I Borras-Linares, A Perez-Sanchez, ... Journal of Functional Foods 33, 202-210, 2017 | 43 | 2017 |