| The fibroblast growth factor receptor genetic status as a potential predictor of the sensitivity to CH5183284/Debio 1347, a novel selective FGFR inhibitor Y Nakanishi, N Akiyama, T Tsukaguchi, T Fujii, K Sakata, H Sase, T Isobe, ... Molecular cancer therapeutics 13 (11), 2547-2558, 2014 | 135 | 2014 |
| Mechanism of oncogenic signal activation by the novel fusion kinase FGFR3–BAIAP2L1 Y Nakanishi, N Akiyama, T Tsukaguchi, T Fujii, Y Satoh, N Ishii, M Aoki Molecular cancer therapeutics 14 (3), 704-712, 2015 | 72 | 2015 |
| Antibody to CD137 Activated by Extracellular Adenosine Triphosphate Is Tumor Selective and Broadly Effective In Vivo without Systemic Immune Activation M Kamata-Sakurai, Y Narita, Y Hori, T Nemoto, R Uchikawa, M Honda, ... Cancer discovery 11 (1), 158-175, 2021 | 69 | 2021 |
| Activating mutations in PIK3CB confer resistance to PI3K inhibition and define a novel oncogenic role for p110β Y Nakanishi, K Walter, JM Spoerke, C O'Brien, LY Huw, GM Hampton, ... Cancer research 76 (5), 1193-1203, 2016 | 69 | 2016 |
| YES1 Is a Targetable Oncogene in Cancers Harboring YES1 Gene Amplification N Hamanaka, Y Nakanishi, T Mizuno, K Horiguchi-Takei, N Akiyama, ... Cancer research 79 (22), 5734-5745, 2019 | 52 | 2019 |
| A signature-based method for indexing cell cycle phase distribution from microarray profiles H Mizuno, Y Nakanishi, N Ishii, A Sarai, K Kitada BMC genomics 10, 1-10, 2009 | 41 | 2009 |
| Functional analysis and subcellular location of two flavohemoglobins from Aspergillus oryzae S Zhou, S Fushinobu, SW Kim, Y Nakanishi, J Maruyama, K Kitamoto, ... Fungal Genetics and Biology 48 (2), 200-207, 2011 | 38 | 2011 |
| Cloning and characterization of two flavohemoglobins from Aspergillus oryzae S Zhou, S Fushinobu, Y Nakanishi, SW Kim, T Wakagi, H Shoun Biochemical and Biophysical Research Communications 381 (1), 7-11, 2009 | 38 | 2009 |
| Discovery of [5-Amino-1-(2-methyl-3H-benzimidazol-5-yl)pyrazol-4-yl]-(1H-indol-2-yl)methanone (CH5183284/Debio 1347), An Orally Available and Selective … H Ebiike, N Taka, M Matsushita, M Ohmori, K Takami, I Hyohdoh, ... Journal of medicinal chemistry 59 (23), 10586-10600, 2016 | 35 | 2016 |
| ERK signal suppression and sensitivity to CH5183284/Debio 1347, a selective FGFR inhibitor Y Nakanishi, H Mizuno, H Sase, T Fujii, K Sakata, N Akiyama, Y Aoki, ... Molecular cancer therapeutics 14 (12), 2831-2839, 2015 | 31 | 2015 |
| A Eukaryotic Copper-Containing Nitrite Reductase Derived from a NirK Homolog Gene of Aspergillus oryzae Y Nakanishi, S Zhou, SW Kim, S Fushinobu, J Maruyama, K Kitamoto, ... Bioscience, biotechnology, and biochemistry 74 (5), 984-991, 2010 | 29 | 2010 |
| Preclinical antitumor activity of the novel heat shock protein 90 inhibitor CH5164840 against human epidermal growth factor receptor 2 (HER2)‐overexpressing cancers N Ono, T Yamazaki, Y Nakanishi, T Fujii, K Sakata, Y Tachibana, A Suda, ... Cancer science 103 (2), 342-349, 2012 | 28 | 2012 |
| Aspergillus oryzae flavohemoglobins promote oxidative damage by hydrogen peroxide S Zhou, S Fushinobu, SW Kim, Y Nakanishi, T Wakagi, H Shoun Biochemical and biophysical research communications 394 (3), 558-561, 2010 | 22 | 2010 |
| Treatment with mountain-cultivated ginseng alleviates trimethyltin-induced cognitive impairments in mice via IL-6-dependent JAK2/STAT3/ERK signaling THT Tu, N Sharma, EJ Shin, HQ Tran, YJ Lee, SY Nah, HYP Tran, ... Planta medica 83 (17), 1342-1350, 2017 | 21 | 2017 |
| Distinct enzymatic and cellular characteristics of two secretory phospholipases A2 in the filamentous fungus Aspergillus oryzae T Nakahama, Y Nakanishi, AR Viscomi, K Takaya, K Kitamoto, S Ottonello, ... Fungal Genetics and Biology 47 (4), 318-331, 2010 | 20 | 2010 |
| Method for providing information and information providing system H Aoki, Y Nakanishi, Y Aoki US Patent 10,121,164, 2018 | 19 | 2018 |
| Acquired JHDM1D–BRAF Fusion Confers Resistance to FGFR Inhibition in FGFR2-Amplified Gastric Cancer H Sase, Y Nakanishi, S Aida, K Horiguchi-Takei, N Akiyama, T Fujii, ... Molecular Cancer Therapeutics 17 (10), 2217-2225, 2018 | 18 | 2018 |
| p-Toluenesulfonic acid induced conversion of fluorinated trimethylsilylethynylanilines into aminoacetophenones: versatile precursors for the synthesis of benzoazaheterocycles L Politanskaya, E Tretyakov Synthesis 50 (03), 555-564, 2018 | 16 | 2018 |
| Aminopyrazole derivative N Taka, M Ohmori, K Takami, M Matsushita, T Hayase, I Hyodo, M Kochi, ... US Patent 8,829,199, 2014 | 15 | 2014 |
| FGFR3 fusion gene and pharmaceutical drug targeting same Y Nakanishi, N Akiyama, Y Nishito US Patent 10,689,705, 2020 | 12 | 2020 |
Shinya FushinobuDepartment of Biotechnology, The University of Tokyo在 mail.ecc.u-tokyo.ac.jp 的电子邮件经过验证
Shinya FushinobuDepartment of Biotechnology, The University of Tokyo在 mail.ecc.u-tokyo.ac.jp 的电子邮件经过验证
Mizuno HideakiChugai Pharmaceutical Co., Ltd.在 chugai-pharm.co.jp 的电子邮件经过验证