C2H2 zinc finger proteins greatly expand the human regulatory lexicon HS Najafabadi, S Mnaimneh, FW Schmitges, M Garton, KN Lam, A Yang, ... Nature biotechnology 33 (5), 555-562, 2015 | 372 | 2015 |
Method to generate highly stable D-amino acid analogs of bioactive helical peptides using a mirror image of the entire PDB M Garton, S Nim, TA Stone, KE Wang, CM Deber, PM Kim Proceedings of the National Academy of Sciences 115 (7), 1505-1510, 2018 | 123 | 2018 |
A structural approach reveals how neighbouring C2H2 zinc fingers influence DNA binding specificity M Garton, HS Najafabadi, FW Schmitges, E Radovani, TR Hughes, ... Nucleic acids research 43 (19), 9147-9157, 2015 | 64 | 2015 |
Shifting landscapes of human MTHFR missense-variant effects J Weile, N Kishore, S Sun, R Maaieh, M Verby, R Li, I Fotiadou, ... The American Journal of Human Genetics 108 (7), 1283-1300, 2021 | 50 | 2021 |
Strategies to develop inhibitors of motif-mediated protein-protein interactions as drug leads C Corbi-Verge, M Garton, S Nim, PM Kim Annual review of pharmacology and toxicology 57 (1), 39-60, 2017 | 45 | 2017 |
Non-base-contacting residues enable kaleidoscopic evolution of metazoan C2H2 zinc finger DNA binding HS Najafabadi, M Garton, MT Weirauch, S Mnaimneh, A Yang, PM Kim, ... Genome biology 18, 1-15, 2017 | 40 | 2017 |
A comprehensive model for the recognition of human telomeres by TRF1 M Garton, C Laughton Journal of molecular biology 425 (16), 2910-2921, 2013 | 19 | 2013 |
Interplay of self-association and conformational flexibility in regulating protein function M Garton, SS MacKinnon, A Malevanets, SJ Wodak Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018 | 16 | 2018 |
A computational approach for designing D-proteins with non-canonical amino acid optimised binding affinity M Garton, M Sayadi, PM Kim PLoS One 12 (11), e0187524, 2017 | 14 | 2017 |
Systematically testing human HMBS missense variants to reveal mechanism and pathogenic variation W van Loggerenberg, S Sowlati-Hashjin, J Weile, R Hamilton, A Chawla, ... The American Journal of Human Genetics 110 (10), 1769-1786, 2023 | 13 | 2023 |
Rapid and accurate structure‐based therapeutic peptide design using GPU accelerated thermodynamic integration M Garton, C Corbi‐Verge, Y Hu, S Nim, N Tarasova, B Sherborne, ... Proteins: Structure, Function, and Bioinformatics 87 (3), 236-244, 2019 | 11 | 2019 |
The geometric influence on the Cys2His2 zinc finger domain and functional plasticity AL Mueller, C Corbi-Verge, DO Giganti, DM Ichikawa, JM Spencer, ... Nucleic Acids Research 48 (11), 6382-6402, 2020 | 10 | 2020 |
Dawn of a new era for membrane protein design S Sowlati-Hashjin, A Gandhi, M Garton BioDesign Research 2022, 9791435, 2022 | 7 | 2022 |
ProteinVAE: variational autoencoder for translational protein design S Lyu, S Sowlati-Hashjin, M Garton bioRxiv, 2023.03. 04.531110, 2023 | 5 | 2023 |
Variational autoencoder for design of synthetic viral vector serotypes S Lyu, S Sowlati-Hashjin, M Garton Nature Machine Intelligence 6 (2), 147-160, 2024 | 4 | 2024 |
FAST-STEM: A human pluripotent stem cell engineering toolkit for rapid design-build-test-learn development of human cell-based therapeutic devices AH Rosenstein, R Sambathkumar, BM Murareanu, NK Dhaliwal, F Sun, ... bioRxiv, 2024.05. 23.595541, 2024 | 1 | 2024 |
A Flexible Transgene Integration ‘Landing-Pad’Toolkit in Human Induced Pluripotent Stem Cells Enables Facile Cellular Engineering, Gene Zygosity Control, and Parallel Transgene … AH Rosenstein, M Nguyen, R Al-Attar, D Serra, N Gulati, T Yin, PM Gilbert, ... bioRxiv, 2023.03. 03.531057, 2023 | 1 | 2023 |
ϑ-Spiral Discovery Reveals a New Class of Biological Building Block M Garton | | 2024 |
FAST-STEM: Synthetic Biology Toolkit for Next Generation Regenerative Medicine AH Rosenstein, A Chai, R Sambathkumar, BM Murareanu, NK Dhaliwal, ... | | 2024 |
In-silico method for designing a (d)-polypeptide ligand M Garton, NIM Satra US Patent App. 16/960,792, 2021 | | 2021 |