A structural model for Alzheimer's β-amyloid fibrils based on experimental constraints from solid state NMR AT Petkova, Y Ishii, JJ Balbach, ON Antzutkin, RD Leapman, F Delaglio, ... Proceedings of the National Academy of Sciences 99 (26), 16742-16747, 2002 | 2273 | 2002 |
Self-propagating, molecular-level polymorphism in Alzheimer's ß-amyloid fibrils AT Petkova, RD Leapman, Z Guo, WM Yau, MP Mattson, R Tycko Science 307 (5707), 262-265, 2005 | 1941 | 2005 |
Molecular structural basis for polymorphism in Alzheimer's β-amyloid fibrils AK Paravastu, RD Leapman, WM Yau, R Tycko Proceedings of the National Academy of Sciences 105 (47), 18349-18354, 2008 | 1328 | 2008 |
Targeted Killing of Cancer Cells in Vivo and in Vitro with EGF-Directed Carbon Nanotube-Based Drug Delivery AA Bhirde, V Patel, J Gavard, G Zhang, AA Sousa, A Masedunskas, ... ACS nano 3 (2), 307-316, 2009 | 993 | 2009 |
Amyloid fibril formation by Aβ16-22, a seven-residue fragment of the Alzheimer's β-amyloid peptide, and structural characterization by solid state NMR JJ Balbach, Y Ishii, ON Antzutkin, RD Leapman, NW Rizzo, F Dyda, ... Biochemistry 39 (45), 13748-13759, 2000 | 878 | 2000 |
Study of the edges in the transition metals and their oxides by electron-energy-loss spectroscopy with comparisons to theory RD Leapman, LA Grunes, PL Fejes Physical Review B 26 (2), 614, 1982 | 870 | 1982 |
Biodegradable gold nanovesicles with an ultrastrong plasmonic coupling effect for photoacoustic imaging and photothermal therapy P Huang, J Lin, W Li, P Rong, Z Wang, S Wang, X Wang, X Sun, ... Angewandte Chemie 125 (52), 14208-14214, 2013 | 695 | 2013 |
Peptide conformation and supramolecular organization in amylin fibrils: constraints from solid-state NMR S Luca, WM Yau, R Leapman, R Tycko Biochemistry 46 (47), 13505-13522, 2007 | 658 | 2007 |
Protein oxidation implicated as the primary determinant of bacterial radioresistance MJ Daly, EK Gaidamakova, VY Matrosova, A Vasilenko, M Zhai, ... PLoS biology 5 (4), e92, 2007 | 524 | 2007 |
Multiple quantum solid-state NMR indicates a parallel, not antiparallel, organization of β-sheets in Alzheimer's β-amyloid fibrils ON Antzutkin, JJ Balbach, RD Leapman, NW Rizzo, J Reed, R Tycko Proceedings of the National Academy of Sciences 97 (24), 13045-13050, 2000 | 504 | 2000 |
Layer-specific variation of iron content in cerebral cortex as a source of MRI contrast M Fukunaga, TQ Li, P van Gelderen, JA de Zwart, K Shmueli, B Yao, ... Proceedings of the National Academy of Sciences 107 (8), 3834-3839, 2010 | 461 | 2010 |
Energy-filtering transmission electron microscopy C Deininger, RF Egerton, F Hofer, B Jouffrey, D Krahl, RD Leapman, ... Springer, 2013 | 445 | 2013 |
Oxygen K near-edge fine structure: An electron-energy-loss investigation with comparisons to new theory for selected 3 d Transition-metal oxides LA Grunes, RD Leapman, CN Wilker, R Hoffmann, AB Kunz Physical Review B 25 (12), 7157, 1982 | 438 | 1982 |
Solid state NMR reveals a pH-dependent antiparallel β-sheet registry in fibrils formed by a β-amyloid peptide AT Petkova, G Buntkowsky, F Dyda, RD Leapman, WM Yau, R Tycko Journal of molecular biology 335 (1), 247-260, 2004 | 397 | 2004 |
Seeded growth of β-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure AK Paravastu, I Qahwash, RD Leapman, SC Meredith, R Tycko Proceedings of the National Academy of Sciences 106 (18), 7443-7448, 2009 | 387 | 2009 |
Supramolecular structural constraints on Alzheimer's β-amyloid fibrils from electron microscopy and solid-state nuclear magnetic resonance ON Antzutkin, RD Leapman, JJ Balbach, R Tycko Biochemistry 41 (51), 15436-15450, 2002 | 369 | 2002 |
K, L, and M shell generalized oscillator strengths and ionization cross sections for fast electron collisions RD Leapman, P Rez, DF Mayers The Journal of chemical physics 72 (2), 1232-1243, 1980 | 353 | 1980 |
PSD-95 is required to sustain the molecular organization of the postsynaptic density X Chen, CD Nelson, X Li, CA Winters, R Azzam, AA Sousa, RD Leapman, ... Journal of Neuroscience 31 (17), 6329-6338, 2011 | 335 | 2011 |
Organization of the core structure of the postsynaptic density X Chen, C Winters, R Azzam, X Li, JA Galbraith, RD Leapman, TS Reese Proceedings of the National Academy of Sciences 105 (11), 4453-4458, 2008 | 312 | 2008 |
Chimeric ferritin nanocages for multiple function loading and multimodal imaging X Lin, J Xie, G Niu, F Zhang, H Gao, M Yang, Q Quan, MA Aronova, ... Nano letters 11 (2), 814-819, 2011 | 311 | 2011 |