GABRD encoding a protein for extra- or peri-synaptic GABAA receptors is a susceptibility locus for generalized epilepsies LM Dibbens, HJ Feng, MC Richards, LA Harkin, BL Hodgson, D Scott, ... Human molecular genetics 13 (13), 1315-1319, 2004 | 425 | 2004 |
Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack JA Lopez, O Susanto, MR Jenkins, N Lukoyanova, VR Sutton, RHP Law, ... Blood, The Journal of the American Society of Hematology 121 (14), 2659-2668, 2013 | 290 | 2013 |
Chimeric antigen receptor T cells form nonclassical and potent immune synapses driving rapid cytotoxicity AJ Davenport, RS Cross, KA Watson, Y Liao, W Shi, HM Prince, ... Proceedings of the National Academy of Sciences 115 (9), E2068-E2076, 2018 | 237 | 2018 |
Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time IVJAT Misty R. Jenkins, Jesse A. Rudd-Schmid, Jamie A. Lopez, Kelly ... Journal of Experimental Medicine, 2015 | 225 | 2015 |
The strength of T cell receptor signal controls the polarization of cytotoxic machinery to the immunological synapse MR Jenkins, A Tsun, JC Stinchcombe, GM Griffiths Immunity 31 (4), 621-631, 2009 | 182 | 2009 |
Addition of a prominent epitope affects influenza A virus-specific CD8+ T cell immunodominance hierarchies when antigen is limiting MR Jenkins, R Webby, PC Doherty, SJ Turner The Journal of Immunology 177 (5), 2917-2925, 2006 | 170 | 2006 |
The synapse and cytolytic machinery of cytotoxic T cells MR Jenkins, GM Griffiths Current opinion in immunology 22 (3), 308-313, 2010 | 136 | 2010 |
Cytotoxic T lymphocyte–induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis NJ Waterhouse, VR Sutton, KA Sedelies, A Ciccone, M Jenkins, SJ Turner, ... The Journal of cell biology 173 (1), 133-144, 2006 | 125 | 2006 |
CAR-T cells inflict sequential killing of multiple tumor target cells AJ Davenport, MR Jenkins, RS Cross, CS Yong, HM Prince, DS Ritchie, ... Cancer immunology research 3 (5), 483-494, 2015 | 115 | 2015 |
Centrosome docking at the immunological synapse is controlled by Lck signaling A Tsun, I Qureshi, JC Stinchcombe, MR Jenkins, M De La Roche, ... Journal of Cell Biology 192 (4), 663-674, 2011 | 106 | 2011 |
Heterogeneity of effector phenotype for acute phase and memory influenza A virus-specific CTL MR Jenkins, K Kedzierska, PC Doherty, SJ Turner The Journal of Immunology 179 (1), 64-70, 2007 | 99 | 2007 |
Rapid and unidirectional perforin pore delivery at the cytotoxic immune synapse JA Lopez, MR Jenkins, JA Rudd-Schmidt, AJ Brennan, JC Danne, ... The Journal of Immunology 191 (5), 2328-2334, 2013 | 98 | 2013 |
A childhood epilepsy mutation reveals a role for developmentally regulated splicing of a sodium channel R Xu, EA Thomas, M Jenkins, EV Gazina, C Chiu, SE Heron, JC Mulley, ... Molecular and Cellular Neuroscience 35 (2), 292-301, 2007 | 92 | 2007 |
Towards immunotherapy for pediatric brain tumors SS Wang, P Bandopadhayay, MR Jenkins Trends in immunology 40 (8), 748-761, 2019 | 88 | 2019 |
Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma NA Gherardin, L Loh, L Admojo, AJ Davenport, K Richardson, A Rogers, ... Scientific reports 8 (1), 4159, 2018 | 80 | 2018 |
Repurposed JAK1/JAK2 inhibitor reverses established autoimmune insulitis in NOD mice PM Trivedi, KL Graham, NA Scott, MR Jenkins, S Majaw, RM Sutherland, ... Diabetes 66 (6), 1650-1660, 2017 | 77 | 2017 |
Location rather than CD62L phenotype is critical in the early establishment of influenza-specific CD8+ T cell memory K Kedzierska, J Stambas, MR Jenkins, R Keating, SJ Turner, PC Doherty Proceedings of the National Academy of Sciences 104 (23), 9782-9787, 2007 | 64 | 2007 |
Cell cycle-related acquisition of cytotoxic mediators defines the progressive differentiation to effector status for virus-specific CD8+ T cells MR Jenkins, J Mintern, NL La Gruta, K Kedzierska, PC Doherty, SJ Turner The Journal of Immunology 181 (6), 3818-3822, 2008 | 62 | 2008 |
Finding the keys to the CAR: identifying novel target antigens for T cell redirection immunotherapies RC Abbott, RS Cross, MR Jenkins International Journal of Molecular Sciences 21 (2), 515, 2020 | 48 | 2020 |
PD-1 blockade enhances elotuzumab efficacy in mouse tumor models NA Bezman, A Jhatakia, AY Kearney, T Brender, M Maurer, K Henning, ... Blood advances 1 (12), 753-765, 2017 | 47 | 2017 |