Next‐generation antimalarial drugs: hybrid molecules as a new strategy in drug design FW Muregi, A Ishih Drug development research 71 (1), 20-32, 2010 | 382 | 2010 |
In vitro antiplasmodial activity of some plants used in Kisii, Kenya against malaria and their chloroquine potentiation effects FW Muregi, SC Chhabra, ENM Njagi, CC Lang'at-Thoruwa, WM Njue, ... Journal of Ethnopharmacology 84 (2-3), 235-239, 2003 | 159 | 2003 |
Antimalarial activity of methanolic extracts from plants used in Kenyan ethnomedicine and their interactions with chloroquine (CQ) against a CQ-tolerant rodent parasite, in mice FW Muregi, A Ishih, T Miyase, T Suzuki, H Kino, T Amano, GM Mkoji, ... Journal of Ethnopharmacology 111 (1), 190-195, 2007 | 158 | 2007 |
Anti‐plasmodial activity of some Kenyan medicinal plant extracts singly and in combination with chloroquine FW Muregi, SC Chhabra, ENM Njagi, CC Lang'at‐Thoruwa, WM Njue, ... Phytotherapy Research: An International Journal Devoted to Pharmacological …, 2004 | 102 | 2004 |
Antiplasmodial Triterpenoids from Ekebergia capensis T Murata, T Miyase, FW Muregi, Y Naoshima-Ishibashi, K Umehara, ... Journal of natural products 71 (2), 167-174, 2008 | 93 | 2008 |
Anti-plasmodial activity of the extracts of some Kenyan medicinal plants GM Rukunga, JW Gathirwa, SA Omar, FW Muregi, CN Muthaura, ... Journal of Ethnopharmacology 121 (2), 282-285, 2009 | 88 | 2009 |
In Vivo antimalarial activity of aqueous extracts from Kenyan medicinal plants and their Chloroquine (CQ) potentiation effects against a blood‐induced CQ‐resistant … FW Muregi, A Ishih, T Suzuki, H Kino, T Amano, GM Mkoji, T Miyase, ... Phytotherapy Research: An International Journal Devoted to Pharmacological …, 2007 | 61 | 2007 |
Anti-plasmodial activity of the extracts and two sesquiterpenes from Cyperus articulatus GM Rukunga, FW Muregi, SA Omar, JW Gathirwa, CN Muthaura, ... Fitoterapia 79 (3), 188-190, 2008 | 57 | 2008 |
The antiplasmodial activity of spermine alkaloids isolated from Albizia gummifera GM Rukunga, FW Muregi, FM Tolo, SA Omar, P Mwitari, CN Muthaura, ... Fitoterapia 78 (7-8), 455-459, 2007 | 56 | 2007 |
Novel rational drug design strategies with potential to revolutionize malaria chemotherapy F W Muregi, P G Kirira, A Ishih Current medicinal chemistry 18 (1), 113-143, 2011 | 48 | 2011 |
Antiplasmodial and cytotoxic activities of extracts of selected medicinal plants used to treat malaria in Embu County, Kenya B Waiganjo, G Moriasi, J Onyancha, N Elias, F Muregi Journal of Parasitology Research 2020 (1), 8871375, 2020 | 30 | 2020 |
Combating antibiotic resistance using guidelines and enhanced stewardship in Kenya: a protocol for an implementation science approach J Gitaka, M Kamita, D Mureithi, D Ndegwa, M Masika, G Omuse, M Ngari, ... BMJ open 10 (3), e030823, 2020 | 23 | 2020 |
Resistance of a rodent malaria parasite to a thymidylate synthase inhibitor induces an apoptotic parasite death and imposes a huge cost of fitness FW Muregi, I Ohta, U Masato, H Kino, A Ishih PloS one 6 (6), e21251, 2011 | 21 | 2011 |
Antimalarial drugs and their useful therapeutic lives: rational drug design lessons from pleiotropic action of quinolines and artemisinins F W Muregi Current drug discovery technologies 7 (4), 280-316, 2010 | 21 | 2010 |
Chloroquine efficacy in Plasmodium berghei NK65-infected ICR mice, with reference to the influence of initial parasite load and starting day of drug administration on the … A Ishih, T Suzki, FW Muregi, K Matsui, M Terada Southeast Asian journal of tropical medicine and public health 37 (1), 13, 2006 | 17 | 2006 |
Gametocyte clearance in children, from western Kenya, with uncomplicated Plasmodium falciparum malaria after artemether–lumefantrine or dihydroartemisinin … P Omondi, M Burugu, D Matoke-Muhia, E Too, EA Nambati, W Chege, ... Malaria Journal 18, 1-9, 2019 | 16 | 2019 |
Comparative anti-oxidant activity of aqueous and organic extracts from Kenyan Ruellia lineari-bracteolata and Ruellia bignoniiflora CO Wangia, JA Orwa, FW Muregi, PG Kareru, K Cheruiyot, J Kibet European Journal of medicinal plants 17 (11), 1-7, 2016 | 16 | 2016 |
Fitness cost of resistance for lumefantrine and piperaquine-resistant Plasmodium berghei in a mouse model WR Gimode, DM Kiboi, FT Kimani, HN Wamakima, MW Burugu, ... Malaria journal 14, 1-11, 2015 | 16 | 2015 |
Novel drug targets in malaria parasite with potential to yield antimalarial drugs with long useful therapeutic lives F W Muregi, H Nyakio Wamakima, F T Kimani Current pharmaceutical design 18 (24), 3505-3521, 2012 | 16 | 2012 |
Plasmodium berghei: efficacy of 5-fluoroorotate in combination with commonly used antimalarial drugs in a mouse model FW Muregi, S Kano, H Kino, A Ishih Experimental parasitology 121 (4), 376-380, 2009 | 16 | 2009 |