Metabolic heterogeneity in human lung tumors CT Hensley, B Faubert, Q Yuan, N Lev-Cohain, E Jin, J Kim, L Jiang, B Ko, ... Cell 164 (4), 681-694, 2016 | 981 | 2016 |
Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport C Yang, B Ko, CT Hensley, L Jiang, AT Wasti, J Kim, J Sudderth, ... Molecular cell 56 (3), 414-424, 2014 | 672 | 2014 |
Reductive carboxylation supports redox homeostasis during anchorage-independent growth L Jiang, AA Shestov, P Swain, C Yang, SJ Parker, QA Wang, LS Terada, ... Nature 532 (7598), 255-258, 2016 | 594 | 2016 |
A role for the mitochondrial pyruvate carrier as a repressor of the Warburg effect and colon cancer cell growth JC Schell, KA Olson, L Jiang, AJ Hawkins, JG Van Vranken, J Xie, ... Molecular cell 56 (3), 400-413, 2014 | 374 | 2014 |
Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects AR Mullen, Z Hu, X Shi, L Jiang, LK Boroughs, Z Kovacs, R Boriack, ... Cell reports 7 (5), 1679-1690, 2014 | 369 | 2014 |
Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism JC Schell, DR Wisidagama, C Bensard, H Zhao, P Wei, J Tanner, A Flores, ... Nature cell biology 19 (9), 1027-1036, 2017 | 282 | 2017 |
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1–AMPK signalling R Lin, S Elf, C Shan, HB Kang, Q Ji, L Zhou, T Hitosugi, L Zhang, S Zhang, ... Nature cell biology 17 (11), 1484-1496, 2015 | 269 | 2015 |
Global analysis of plasma lipids identifies liver-derived acylcarnitines as a fuel source for brown fat thermogenesis J Simcox, G Geoghegan, JA Maschek, CL Bensard, M Pasquali, R Miao, ... Cell metabolism 26 (3), 509-522. e6, 2017 | 225 | 2017 |
Abrogation of hepatic ATP‐citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor‐deficient mice Q Wang, L Jiang, J Wang, S Li, Y Yu, J You, R Zeng, X Gao, L Rui, W Li, ... Hepatology 49 (4), 1166-1175, 2009 | 225 | 2009 |
R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis Y Qing, L Dong, L Gao, C Li, Y Li, L Han, E Prince, B Tan, X Deng, ... Molecular cell 81 (5), 922-939. e9, 2021 | 213 | 2021 |
Metabolic reprogramming during TGFβ1-induced epithelial-to-mesenchymal transition L Jiang, L Xiao, H Sugiura, X Huang, A Ali, M Kuro-o, RJ Deberardinis, ... Oncogene 34 (30), 3908-3916, 2015 | 212 | 2015 |
Low-and high-thermogenic brown adipocyte subpopulations coexist in murine adipose tissue A Song, W Dai, MJ Jang, L Medrano, Z Li, H Zhao, M Shao, J Tan, A Li, ... The Journal of clinical investigation 130 (1), 247-257, 2020 | 172 | 2020 |
Reversible de-differentiation of mature white adipocytes into preadipocyte-like precursors during lactation QA Wang, A Song, W Chen, PC Schwalie, F Zhang, L Vishvanath, L Jiang, ... Cell metabolism 28 (2), 282-288. e3, 2018 | 160 | 2018 |
Dysregulated mitochondrial dynamics and metabolism in obesity, diabetes, and cancer W Dai, L Jiang Frontiers in endocrinology 10, 570, 2019 | 153 | 2019 |
Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth C Shan, S Elf, Q Ji, HB Kang, L Zhou, T Hitosugi, L Jin, R Lin, L Zhang, ... Molecular cell 55 (4), 552-565, 2014 | 144 | 2014 |
Distinct regulatory mechanisms governing embryonic versus adult adipocyte maturation QA Wang, C Tao, L Jiang, M Shao, R Ye, Y Zhu, R Gordillo, A Ali, Y Lian, ... Nature cell biology 17 (9), 1099-1111, 2015 | 141 | 2015 |
Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction CT Cheng, Y Qi, YC Wang, KK Chi, Y Chung, C Ouyang, YR Chen, ... Communications Biology 1 (1), 178, 2018 | 127 | 2018 |
PKA phosphorylation couples hepatic inositol-requiring enzyme 1α to glucagon signaling in glucose metabolism T Mao, M Shao, Y Qiu, J Huang, Y Zhang, B Song, Q Wang, L Jiang, Y Liu, ... Proceedings of the National Academy of Sciences 108 (38), 15852-15857, 2011 | 114 | 2011 |
Analysis of hypoxia-induced metabolic reprogramming C Yang, L Jiang, H Zhang, LA Shimoda, RJ DeBerardinis, GL Semenza Methods in enzymology 542, 425-455, 2014 | 112 | 2014 |
Leptin contributes to the adaptive responses of mice to high-fat diet intake through suppressing the lipogenic pathway L Jiang, Q Wang, Y Yu, F Zhao, P Huang, R Zeng, RZ Qi, W Li, Y Liu PLoS One 4 (9), e6884, 2009 | 110 | 2009 |